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Overview

Oflobe-Dx Eye/Ear Drops

Manufacturer :  Sapient Laboratories Pvt Ltd
Medicine Composition :  Ofloxacin, Dexamethasone, Benzalkonium Chloride
Prescription vs OTC : Prescription by Doctor required

About Oflobe-Dx Eye/Ear Drops

Oflobe-Dx Eye/Ear Drops is an antibiotic drug that fights against bacterial infections. It is used in the treatment of infections that are caused by bacteria, such as chronic bronchitis, pneumonia, tuberculosis, gonorrhea, Chlamydia, anthrax and plague. This anti-biotic also treats bacterial infections of the skin, ears, eyes, sinus, pelvis, urinary tract, bladder, cervix, urethra and the respiratory system.

Oflobe-Dx Eye/Ear Drops inhibits the production of certain enzymes in the DNA of a bacteria, which are necessary for the survival and growth of this bacterial infection. Therefore, this antibiotic drug fights against bacterial infections by killing the bacteria and inhibiting the process of bacterial cell division.

Oflobe-Dx Eye/Ear Drops is an antibiotic medicine that kills bacteria and hinders their growth. This antibiotic is a part of a class of drugs called fluoroquinolones, which work to treat infections that have been caused by bacteria. It is highly effective in treating conditions such as infectious diarrhea, cellulitis, prostatitis, plague, pneumonia and tuberculosis. Oflobe-Dx Eye/Ear Drops also helps treat bacterial infections of the urethra, cervix, urinary tract, bladder, bones, skin, ears, nose and eyes.

Oflobe-Dx Eye/Ear Drops fights against both Gram-negative as well as Gram-positive bacteria. It damages double stranded bacterial DNA and hinders DNA relaxation, thus inhibiting the synthesis of bacterial DNA. In this way, Oflobe-Dx Eye/Ear Drops inhibits the process of cell division for bacterial DNA, which helps you to get rid of a bacterial infection.

Oflobe-Dx Eye/Ear Drops is available in the form of tablets or capsules that are taken orally, in the form of eye or ear drops and can also be injected intravenously. It is advisable to take this medication only under the strict guidelines of your doctor. Follow this prescription through until the course is complete, even if the symptoms disappear. You should not skip a dose and avoid taking an extra tablet to make up for it.

It is possible for some people to experience a few common side effects from taking Oflobe-Dx Eye/Ear Drops like headaches, diarrhea, nausea, vomiting, trouble sleeping and dry mouth. These side effects are minor and may not require medical attention, unless they persist for over a week. However, there are certain severe side effects such as hallucinations, tendonitis, mood swings, anxiety, irregular heartbeat, fatigue and a numbing sensation of the feet or hands. Not everyone experiences these side effects, it occurs only in a few cases. If you do experience any of these side effects, seek medical help immediately. If you are allergic to Oflobe-Dx Eye/Ear Drops, you might experience symptoms such as itchiness, swollen tongue, face, throat, hands or feet, trouble breathing and rashes. You should stop taking this medicine as soon as you manifest any of these symptoms and contact your doctor immediately.

Some people are more likely to face harmful side effects, if they also suffer from other conditions like brain disorders, seizures, heart conditions, kidney problems, myasthenia gravis, liver disease, epilepsy, tendonitis, an antibiotic allergy, bone disorders and problems of the joints. It is advisable to inform your doctor of these conditions beforehand, if he/she recommends taking Oflobe-Dx Eye/Ear Drops. It is advisable for pregnant women, women who are breastfeeding and children below 16 years, to avoid taking this antibiotic, since it can lead to harmful consequences.

    What are the uses of Oflobe-Dx Eye/Ear Drops

    What are the contraindications of Oflobe-Dx Eye/Ear Drops ?

    What are the side effects of Oflobe-Dx Eye/Ear Drops ?

    • Blurred Vision

    • Eye Irritation

    • Eye Discomfort

    • Increased Intraocular Pressure

    Key highlights of Oflobe-Dx Eye/Ear Drops

    • How long is the duration of effect?

      The effect of this medicine lasts for a duration of 12 to 20 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

    • Are there any pregnancy warnings?

      Use of this medicine is not recommended in pregnant women. Use only if clearly needed under the supervision of the doctor.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Use of this medicine is not recommended in women who breastfeed due to the adverse effect on development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Avoid breastfeeding for about 3 to 4 hours to decrease the infant's risk exposure. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

    What are the substitutes for Oflobe-Dx Eye/Ear Drops ?

    Below is the list of medicines, which have the same composition, strength and form as Oflobe-Dx Eye/Ear Drops , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    How does this medication work?

    This drop is a combination of Ofloxacin and Dexamethasone. The active ingredients fall under the class of fluoroquinolones and corticosteroid, respectively. This medicine alleviates the symptoms of the patient by working via a dual mechanism of action.

    Firstly, it works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death. It also works by reducing the excitation of the brain cells by inhibiting the sodium channels thus inhibits the repetitive firing of brain cells.

    Secondly, it enters the cells through passive diffusion and binds to glucocorticoid receptors, forming a complex. This complex undergoes activation, enters the cell nucleus and binds to the DNA. This induces the natural effects of biological hormones.

      What are the interactions of Oflobe-Dx Eye/Ear Drops ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Lab

        It cause prolongation of prothrombin time. Also elevation in serum triglycerides, cholesterol, potassium, liver function tests are reported.
      • Interaction with Medicine

        Corticosteroids

        You may experience pain, swelling, or inflammation in ankle, shoulder, hand, or thumb if these medicines are used together. This interaction is more likely to occur in elderly population who have undergone a kidney or heart transplantation. Replacement of the medicine should be made under the doctor's supervision.

        Escitalopram

        You may experience dizziness, lightheadedness, shortness of breath, or heart palpitations if these medicines are used together. This interaction is more likely to happen if you suffer from any heart disease (Arrhythmia) or have a family history of Arrhythmia. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

        Quinidine

        You may experience dizziness, lightheadedness, and heart palpitations if these medicines are used together. Regular cardiac function tests are to be performed if you have any heart disease (Arrhythmia) or a family history of Arrhythmia. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

        Antidiabetic medicines

        You may experience hypoglycemic effects like dizziness, headache, nervousness, confusion, tremor and weakness if these medicines are used together. Hyperglycemic effects like increased thirst, urination and hunger are less likely to occur. Regular blood glucose checkups are to be performed if you are diabetic or has any kidney disease. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

        Aspirin

        You may experience tremors, involuntary muscle movements, hallucinations, or seizures if these medicines are used together. This interaction is more likely to happen if you have a history of seizures or family history of seizures. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

        Ethinyl Estradiol

        The desired effect of contraceptive pills will not be achieved if these medicines are used together. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.
      • Interaction with Disease

        Central Nervous System Depression

        If you suffer from CNS disorder and you take Oflobe-Dx Eye/Ear Drops, then you may experience tremors, restlessness, anxiety, confusion and hallucinations. Avoid consuming caffeine containing products like coffee, chocolates and energy drinks.

        Colitis

        Avoid taking Oflobe-Dx Eye/Ear Drops if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

        Qt Prolongation

        Avoid using Oflobe-Dx Eye/Ear Drops if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.
      • Interaction with Food

        Dairy products

        The desired effect of Oflobe-Dx Eye/Ear Drops is not observed if consumed with dairy products. There should be at least 2 hours gap between taking Oflobe-Dx Eye/Ear Drops and dairy products.

      FAQs about Oflobe-Dx Eye/Ear Drops

      • Ques : What is Oflobe-Dx Eye/Ear Drops?

        Ans : This medication is a combination of Ofloxacin and Dexamethasone. This medicine performs its action by obstructing the production of bacteria in the bacterial cell wall.

      • Ques : How long do I need to use Oflobe-Dx Eye/Ear Drops before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Oflobe-Dx Eye/Ear Drops?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Oflobe-Dx Eye/Ear Drops empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Oflobe-Dx Eye/Ear Drops?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Ofloxacin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ofloxacin

      • Ofloxacin- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 1 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB01165

      • Dexamethasone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/dexamethasone

      • Dexamethasone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB01234

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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