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Overview

Ofuxin 200 MG Injection

Manufacturer :  Neon Laboratories Ltd
Medicine Composition :  Ofloxacin
Prescription vs OTC : Prescription by Doctor required

About Ofuxin 200 MG Injection

Ofuxin 200 MG Injection is an antibiotic drug that fights against bacterial infections. It is used in the treatment of infections that are caused by bacteria, such as chronic bronchitis, pneumonia, tuberculosis, gonorrhea, Chlamydia, anthrax and plague. This anti-biotic also treats bacterial infections of the skin, ears, eyes, sinus, pelvis, urinary tract, bladder, cervix, urethra and the respiratory system.

Ofuxin 200 MG Injection inhibits the production of certain enzymes in the DNA of a bacteria, which are necessary for the survival and growth of this bacterial infection. Therefore, this antibiotic drug fights against bacterial infections by killing the bacteria and inhibiting the process of bacterial cell division.

Ofuxin 200 MG Injection is an antibiotic medicine that kills bacteria and hinders their growth. This antibiotic is a part of a class of drugs called fluoroquinolones, which work to treat infections that have been caused by bacteria. It is highly effective in treating conditions such as infectious diarrhea, cellulitis, prostatitis, plague, pneumonia and tuberculosis. Ofuxin 200 MG Injection also helps treat bacterial infections of the urethra, cervix, urinary tract, bladder, bones, skin, ears, nose and eyes.

Ofuxin 200 MG Injection fights against both Gram-negative as well as Gram-positive bacteria. It damages double stranded bacterial DNA and hinders DNA relaxation, thus inhibiting the synthesis of bacterial DNA. In this way, Ofuxin 200 MG Injection inhibits the process of cell division for bacterial DNA, which helps you to get rid of a bacterial infection.

Ofuxin 200 MG Injection is injected intravenously and the salt present in it is also available in the form of tablets or capsules that are taken orally, in the form of eye or ear drops. It is advisable to take this medication only under the strict guidelines of your doctor. Follow this prescription through until the course is complete, even if the symptoms disappear. You should not skip a dose and avoid taking an extra dose to make up for it.

It is possible for some people to experience a few common side effects from taking Ofuxin 200 MG Injection like headaches, diarrhea, nausea, vomiting, trouble sleeping and dry mouth. These side effects are minor and may not require medical attention, unless they persist for over a week. However, there are certain severe side effects such as hallucinations, tendonitis, mood swings, anxiety, irregular heartbeat, fatigue and a numbing sensation of the feet or hands. Not everyone experiences these side effects, it occurs only in a few cases. If you do experience any of these side effects, seek medical help immediately. If you are allergic to Ofuxin 200 MG Injection, you might experience symptoms such as itchiness, swollen tongue, face, throat, hands or feet, trouble breathing and rashes. You should stop taking this medicine as soon as you manifest any of these symptoms and contact your doctor immediately.

Some people are more likely to face harmful side effects, if they also suffer from other conditions like brain disorders, seizures, heart conditions, kidney problems, myasthenia gravis, liver disease, epilepsy, tendonitis, an antibiotic allergy, bone disorders and problems of the joints. It is advisable to inform your doctor of these conditions beforehand, if he/she recommends taking Ofuxin 200 MG Injection. It is advisable for pregnant women, women who are breastfeeding and children below 16 years, to avoid taking this antibiotic, since it can lead to harmful consequences.

    What are the uses of Ofuxin 200 MG Injection

    • Pneumonia

      Ofuxin 200 MG Injection is used in the treatment of Community-Acquired Pneumonia, a type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

    • Bronchitis

      Ofuxin 200 MG Injection is used to treat bronchitis, an inflammation in lungs caused by Streptococcus pneumoniae, Haemophilus influenzae and Mycoplasma Pneumonia.

    • Pyelonephritis

      Ofuxin 200 MG Injection helps against Pyelonephritis, a kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

    • Cystitis

      Ofuxin 200 MG Injection treats cystitis, a bladder infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

    • Prostatitis

      Ofuxin 200 MG Injection is used in the treatment of Prostatitis (inflammation of the prostate gland that produces semen) caused by Escherichia coli, Pseudomonas and Enterococcus species.

    • Gonococcal Infection

      Ofuxin 200 MG Injection is used in the treatment of Gonococcal infection which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.

    • Joint Infection

      Ofuxin 200 MG Injection is used in the treatment of bone and joint infections caused by Enterobacter cloacae, Pseudomonas aeruginosa.

    • Pneumonia With Cystic Fibrosis

      Ofuxin 200 MG Injection is used in the treatment of Pneumonia with Cystic Fibrosis (an inherited disease that causes thick mucus to build up in the lungs and promotes the growth of bacteria like Staphylococcus aureus and Hemophilus influenzae).

    What are the contraindications of Ofuxin 200 MG Injection ?

    • Allergy

      Avoid taking Ofuxin 200 MG Injection if you have a known allergy to this medicine or any other medicines belonging to the class fluoroquinolones.

    • Tendinitis Or Tendon Rupture

      Avoid taking this medicineif you have a past history of tendinitis or tendon rupture after using Ofuxin 200 MG Injection.

    • Myasthenia Gravis

      Avoid taking this medicine if you have a past or family history of suffering from Myasthenia Gravis (weakness and rapid fatigue of muscles under voluntary control).

    What are the side effects of Ofuxin 200 MG Injection ?

    • Diarrhoea

    • Abdominal Pain

    • White Patches In The Mouth Or On The Tongue

    • Joint Pain

    • Black Or Tarry Stools

    • Fever With Chills

    • Chest Tightness

    • Ringing Or Buzzing In The Ears

    • Muscle Pain

    • Numbness Of The Hands

    • Swelling Of Face, Lips, Eyelids, Tongue, Hands And Feet

    • Running Nose

    • Sneezing

    Key highlights of Ofuxin 200 MG Injection

    • How long is the duration of effect?

      The effect of this medicine lasts for a duration of 12 to 20 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

    • Are there any pregnancy warnings?

      Use of this medicine is not recommended in pregnant women. Use only if clearly needed under the supervision of the doctor.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Use of this medicine is not recommended in women who breastfeed due to the adverse effect on development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Avoid breastfeeding for about 3 to 4 hours to decrease the infant's risk exposure. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

    What are the substitutes for Ofuxin 200 MG Injection ?

    Below is the list of medicines, which have the same composition, strength and form as Ofuxin 200 MG Injection , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    How does this medication work?

    Ofuxin 200 MG Injection belongs to the class fluoroquinolones. It works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.

      What are the interactions of Ofuxin 200 MG Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Corticosteroids

        You may experience pain, swelling, or inflammation in ankle, shoulder, hand, or thumb if these medicines are used together. This interaction is more likely to occur in elderly population who have undergone a kidney or heart transplantation. Replacement of the medicine should be made under the doctor's supervision.

        Escitalopram

        You may experience dizziness, lightheadedness, shortness of breath, or heart palpitations if these medicines are used together. This interaction is more likely to happen if you suffer from any heart disease (Arrhythmia) or have a family history of Arrhythmia. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

        Quinidine

        You may experience dizziness, lightheadedness, and heart palpitations if these medicines are used together. Regular cardiac function tests are to be performed if you have any heart disease (Arrhythmia) or a family history of Arrhythmia. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

        Antidiabetic medicines

        You may experience hypoglycemic effects like dizziness, headache, nervousness, confusion, tremor and weakness if these medicines are used together. Hyperglycemic effects like increased thirst, urination and hunger are less likely to occur. Regular blood glucose checkups are to be performed if you are diabetic or has any kidney disease. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

        Aspirin

        You may experience tremors, involuntary muscle movements, hallucinations, or seizures if these medicines are used together. This interaction is more likely to happen if you have a history of seizures or family history of seizures. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

        Ethinyl Estradiol

        The desired effect of contraceptive pills will not be achieved if these medicines are used together. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.
      • Interaction with Disease

        Central Nervous System Depression

        If you suffer from CNS disorder and you take Ofuxin 200 MG Injection, then you may experience tremors, restlessness, anxiety, confusion and hallucinations. Avoid consuming caffeine containing products like coffee, chocolates and energy drinks.

        Colitis

        Avoid taking Ofuxin 200 MG Injection if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

        Qt Prolongation

        Avoid using Ofuxin 200 MG Injection if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.
      • Interaction with Food

        Dairy products

        The desired effect of Ofuxin 200 MG Injection is not observed if consumed with dairy products. There should be at least 2 hours gap between taking Ofuxin 200 MG Injection and dairy products.
      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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