Ondem 4 MG Tablet MD

Ondem 4 MG Tablet MD is prescribed for the treatment of nausea as well as vomiting, caused by other medical treatments such as surgery, chemotherapy and radiation. This belongs to the antiemetics class of drugs. This medicine work by blocking the chemical serotonin from releasing in your gut and your central nervous system. This will prevent vomiting and nausea.

Ondem 4 MG Tablet MD is available in four different forms that can be taken orally; tablet, disintegrating (dissolving) tablet, solution and film. It also comes in an IV (intravenous) form that can be injected to your body by a doctor. You can take it with food or without food.

This medicine can be used alone as well as in a combination with other medicines for preventing vomiting and nausea that one experiences after a surgery, chemotherapy or radiation session.

Your doctor must be informed if you are allergic to Ondem 4 MG Tablet MD as well as other medications that block serotonin, along with any other allergies that you have. He/ She must also know about your medical history and if you had problems such as:

• Liver disease,
• Irregular heartbeat,
• Stomach or intestinal problems in the past.

Apart from that, you must also inform the doctor if you are under any medication for depression or any psychiatric disorder. The dosage of Ondem 4 MG Tablet MD is decided after taking your medical condition into account and how responsive your body is to therapy. In the case of children, the dose also depends on their weight and age.

If you are undergoing chemotherapy, you need to take Ondem 4 MG Tablet MD orally half an hour before your treatment starts. In case of radiation, take it 1-2 hours before the procedure of treatment begins. For preventing nausea before surgery, it is advised to take the medication an hour before your surgery.

In case you miss a dose, you can take the medication once you remember it. If it is already time for the next dose, ensure that you do not take two doses to make up for the missed dose. Overdose of Ondem 4 MG Tablet MD can lead to severe constipation, faint spells or feeling light-headed.

The side effects of Ondem 4 MG Tablet MD can include dizziness, drowsiness, diarrhea, constipation and headache. These side effects are usually mild in nature and go away in a few days or 1-2 weeks. You can consult your doctor if these symptoms remain for a long time. There are some serious side effects that Ondem 4 MG Tablet MD may have, which would require immediate medical supervision.

• Nausea Or Vomiting

• Nausea

• Hypersensitivity

• Headache

• Dizziness

• Abdominal Discomfort

• Constipation

• Rash

• Wheezing

• Bronchospasm

• Fatigue

• Painful Urination

• Fever

• Dry Mouth

• Anxiety

• How long is the duration of effect?

  The effect of Ondem lasts for about 12 to 28 hours since the medicine is predominantly excreted through urine.

• What is the onset of action?

  Within 2 hours after consumption, the peak effects of the medicine are observed. The intravenous form of the medicine shows peak effects within 30 minutes.

• Are there any pregnancy warnings?

  Ondem must not be consumed by pregnant women. A doctor must be consulted for more details.

• Is it habit forming?

  Ondem doesn’t have any habit forming tendencies.

• Are there any breast-feeding warnings?

  Ondem must not be used by breastfeeding women since there is no absolute data that talks about excretion through human breast milk.

• Is It safe with alcohol?

  Alcohol and its effects with the medicine have not been clinically acquired yet. The doctor must be consulted before consuming alcohol during the treatment.

• Is it safe to drive while on this medicine?

  Ondem can cause drowsiness in the patient, which can be very dangerous while driving. The patient must refrain from performing any activity that requires alertness in the patient.

• Does this affect kidney function?

  For patients suffering from any kidney abnormalities, the consumption of Ondem can cause kidney disorders such as kidney failure. Consulting the doctor before consumption is a prudent idea.

• Does this affect liver function?

  Patients that have a history of liver damage must not consume the medicine as it can cause a high increase in the level of liver enzymes.

Below is the list of medicines, which have the same composition, strength and form as Ondem 4 MG Tablet MD , and hence can be used as its substitute.

• Periset 4 MG Tablet MD

  Ipca Laboratories Pvt Ltd.

• Ondamac 4 MG Tablet MD

  Macleods Pharmaceuticals Pvt.Ltd

• Onditron 4 MG Tablet MD

  Wockhardt Ltd

• Onvin 4 MG Tablet MD

  Cadila Pharmaceuticals Ltd

• Vomihalt 4 MG Tablet MD

  Ipca Laboratories Pvt Ltd.

• Are there any overdose instructions?

  If the patient overdoses, the doctor must be consulted immediately and medical attention must be provided as soon as possible.

• Are there any missed dose instructions?

  For Ondem, the patient must take the missed dose as soon as possible and skip the dose if the time for the next dose as scheduled occurs. Doubling the dose is not advisable.

This drug works by blocking 5-HT3 receptors peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Ondem 4 MG Tablet MD causes hypokalemia, thus monitoring of potassium serum concentration is recommended.

• Interaction with Medicine

  • Apomorphine : Use of Ondansetron with Apomorphine is not recommended. Replacement of the drug should be considered under the doctor's supervision. Usage of other medicines should be reported to the doctor.
  • Amiodarone : Use of Ondansetron with Amiodarone is not recommended as it may cause dizziness, lightheadedness, difficulty in breathing if these drugs are used together. Regular cardiac function tests are to be performed if the patient is having any heart disease. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.
  • Amitriptyline : If these drugs are used together, the patient may experience confusion, hallucination, changes in blood pressure, fever or excessive sweating. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.
  • Carbamazepine : Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.
  • Phenytoin : Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.
  • Cyclophosphamide : The desired effect of cyclophosphamide will not be obtained if these drugs are concurrently taken. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.

• Interaction with Disease

  • Qt Prolongation : Details of any heart disease, family history of an arrhythmia or any other drugs that cause QT interval prolongation (eg: Antipsychotics, Arrhythmia drugs) should be reported to the doctor. Regular cardiac function tests are to be performed if the patient is having any heart disease.
  • Liver Disease : Details of any liver disease (jaundice, hepatitis) or other drugs that may affect the liver (eg: TB drugs, HIV drugs) should be reported to the doctor. Regular liver function tests are to be performed if the patient is having any liver disease.

• Ques : What is Ondem 4 MG Tablet MD?

  Ans : Ondem is a medication which contains Ondansetron as an active ingredients in it. It performs its actions by restricting the action of a serotonin (chemical messenger ) in the brain that may cause nausea and vomiting during anti-cancer treatment known as chemotherapy or after surgery.

• Ques : What is Ondem 4 MG Tablet MD used for?

  Ans :

  Ondem 4 mg tablet MD is a medication that is used to treat, control, and prevent the Below mentioned conditions, which are as follows:

  1. Nausea and vomiting
  2. Chemotherapy induced nausea and vomiting
  3. Post-operative nausea and vomiting

• Ques : What are the side effects of Ondem 4 MG Tablet MD?

  Ans : Side effects include headache, dizziness, constipation etc.

• Ques : Can Ondem 4 MG Tablet MD make you sleepy?

  Ans : Ondansetron which is an active ingredient of Ondem. It may cause sleepiness/dizziness. If you are observing such conditions, please consult your doctor.

• Ques : How long do I need to use Ondem 4 MG Tablet MD before I see improvement of my conditions?

  Ans : This medication should be consumed, till the complete eradication of disease. Thus it is advised to use, till the time directed by your doctor and moreover taking this medication longer than it was prescribed, can also cause inadequate effect on the patient. So please consult your doctor.

• Ques : At what frequency do I need to use Ondem 4 MG Tablet MD?

  Ans : This medication is generally used once or twice a day, as the time interval upto which this medication has an impact, is around 12 to 28 hours, but it is not the standard frequency for using this medication. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.

• Ques : Should I use Ondem 4 MG Tablet MD empty stomach, before food or after food?

  Ans : This medication is commonly taken orally from mouth and the action of salts involved in this medication do not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a the day.

• Ques : What are the instructions for storage and disposal of Ondem 4 MG Tablet MD?

  Ans : This medication contains salts, which are suitable to store at room temperature and keeping this medication above or below that, can cause inadequate effect. Protect it from moisture and light. Keep this medication away, from the reach of children. It is advised to dispose the expired or unused medication, for avoiding its inadequate effect.

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  https://druginfo.nlm.nih.gov/drugportal/name/ondansetron

• Ondansetron 4mg Orodispersible Tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 25 April 2019]. Available from:

  https://www.medicines.org.uk/emc/product/10164/smpc

• Important Information About Ondansetron- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 25 April 2019]. Available from:

  https://www.drugsbanks.com/important-information-about-ondansetron/

• ONDANSETRON- ondansetron hydrochloride tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2011 [Cited 25 April 2019]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fc3d39e0-8bf2-4c29-b872-66a1cf8bb2fb