Paclitaxel

Paclitaxel is an anticancer medicine, used in chemotherapy to treat a number of cancers. Primarily it is used in the treatment of breast cancer and ovarian cancer. It is sold under the trade name of Taxol. Paclitaxel is categorized as a plant alkaloid, a taxane and a antimicrotublue agent. Paclitaxel is injected into the body by injection or infusion.

Paclitaxel is a type of irritant that may cause an inflammation of your vein through which it is being given. Other side effects or reactions that you may experience on taking Paclitaxel are nausea, vomiting tendency, hair loss, diarrhea, hypersensitivity, mucositis, skin rash, flushing, blurred vision, numbness, dizziness, fever, paleness, difficulty in breathing, cough, sweating, slow or irregular heartbeat and chest pain. In certain adverse cases, it may cause major arthralgia, myalgia. It is advised that you seek medical attention if you are afflicted with any of these side effects.

Before taking Paclitaxel discuss with your doctor if you have any of the conditions mentioned below:

• If you are taking any prescriptive or over the counter drugs, herbal medications or dietary supplements.
• If you are planning to take any immunization, vaccination or radiation treatment anytime soon.
• If you are pregnant or are planning to become pregnant or are nursing a baby.
• If you have any allergies, bacterial or viral infections.
• If you are under 18 years of age.
• If you have heart, liver, kidney or bone marrow disorders.

Do not get pregnant while under Paclitaxel treatment. Use contraception for both men and women. Should you become pregnant, notify your doctor. The dosage is determined by your doctor according to your individual specifications and condition. The usual dose for treatment in ovarian and breast cancer is of two types; one is giving about 175 mg for three hours every three weeks followed by a Cisplatin therapy. And the second one is giving 135 mg for 24 hours every three weeks followed by the same cisplatin therapy.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Ovarian Cancer

  Paclitaxel is used in the treatment of cancer that affects the female reproductive system.

• Breast Cancer

  Paclitaxel is used in the treatment of breast cancer.

• Non-Small Cell Lung Cancer

  Paclitaxel is used in the treatment of Non-Small Cell Lung Cancer which is a type of cancer that affects the lungs.

• Kaposi's Sarcoma

  Paclitaxel is used in the treatment of Kaposi's Sarcoma which is a type of cancer that develops under the skin in the lining of mouth, nose, and throat.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Allergy

  Not recommended in the patients with known allergy to Paclitaxel.

• Neutrophils Count

  Not recommended in the patients with neutrophils count less than 1,500 cells/mm3

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Neutropenia

• Difficulty In Swallowing

• Dizziness

• Fever

• Pale Skin

• Allergic Skin Reaction

• Mouth Ulcers

• Difficulty In Breathing

• Chest Discomfort

• Swelling And Redness At The Injection Site

• Diarrhoea

• Hair Loss Or Thinning Of The Hair

• Nausea Or Vomiting

• Joint Pain

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 27 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed in less than an hour.

• Are there any pregnancy warnings?

  This medicine is not recommended for pregnant women.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended in breastfeeding women.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• Missed Dose instructions

  It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

Below is the list of medicines, which contains Paclitaxel as ingredient

• Intaxel 30 MG Injection

  Fresenius Kabi India Pvt Ltd

• Paclitax Nab 100 MG Infusion

  Cipla Ltd

• Altaxel Nova 30 MG Injection

  Alkem Laboratories Ltd

• Paxtal 260 MG Infusion

  Abbott Healthcare Pvt. Ltd

• Celtax 30 MG Injection

  Celon Labs

• Mitotax 30 MG Injection

  Dr. Reddys Laboratories Ltd

• Oncotaxel 30 MG Injection

  Sun Pharma Laboratories Ltd

• Nanoxel 300 MG Injection

  Fresenius Kabi India Pvt Ltd

• Altaxel 30 MG Injection

  Alkem Laboratories Ltd

• Cytax 300 MG Infusion

  Intas Pharmaceuticals Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

This medicine belongs to the class antimicrotubule agent. It stabilizes the microtubules by precluding the depolymerization. This results in the hindrance of the normal reorganization dynamics of the microtubule network. This reorganisation is essential for vital interphase and cellular functions like mitotic.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Alcohol

  Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Clozapine

  These medicines may further lower the white blood cell count if received together. Any symptoms of fever, diarrhea, sore throat, chills should be informed to the doctor. Close monitoring of blood cell count is necessary. An alternate medicine should be considered based on the clinical condition.

  Diltiazem

  Diltiazem may increase the concentration of Paclitaxel and may cause serious effects like low white blood cells count, hair loss, nausea, and vomiting. Inform the doctor if you are receiving any antihypertensives before initiation of the treatment. An alternate medicine should be considered based on the clinical condition.

  Atorvastatin

  These medicines may increase the risk of nerve damage if given together. Any symptoms of numbness, tingling or burning sensation in feet, hands should be informed to the doctor. An alternate medicine should be considered based on the clinical condition.

  Live vaccines

  You may be at the risk of developing infections if these medicines are taken together. Inform the doctor if you had received either of these medicines. Your doctor may postpone therapy based on the condition.

• Interaction with Disease

  Cardiac Conduction Abnormalities

  This medicine is known to cause serious heart conduction abnormalities. Inform the doctor if you have any heart diseases. Close monitoring of low blood pressure and decreased heartbeat is necessary.

• Interaction with Food

  Food

  Information not available.

• Paclitaxelt-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/paclitaxel

• Paclitaxel-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

  https://go.drugbank.com/drugs/DB01229

• PACLITAXEL injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=PACLITAXEL