Petril Beta 0.25 Mg/20 Mg Tablet

Petril Beta 0.25 Mg/20 Mg Tablet is a prescription drug that is employed in the treatment of anxiety disorder. This medicine helps calm the brain by reducing the hyperactive and abnormal activity of the nerve cells. It also works by blocking the certain chemical messengers on the blood vessels and heart which in turn reduces the blood pressure and heart rate.

Petril Beta 0.25 Mg/20 Mg Tablet should be taken as instructed by the doctor at the same time every day, it is important to maintain a consistent level of medication in the medicine. This medication has the potential to form a habit, thus, it should be taken with caution.

Petril Beta 0.25 Mg/20 Mg Tablet may induce depression or unusual mood changes, it is important to notify the doctor in case this happens. It is essential to inform the doctor of any allergies, recent medications, and other disorders as it may affect the effectiveness of Petril Beta 0.25 Mg/20 Mg Tablet.

The medicine might not be suitable for everyone as it can have harmful effects on people with certain conditions. Before beginning a course of this medication, you need to notify your doctor if you are-

• Pregnant or breastfeeding, or
• Suffering from conditions such as:
• Asthma,
• Diabetes mellitus,
• Psoriasis,
• Liver or kidney problems,
• Severe heart condition.

The medicine must be taken according to the doctor’s prescription. The doctor might recommend taking it two, three or even four times a day. You must complete the course of this medication otherwise it can cause you to develop withdrawal symptoms.

• Anxiety Disorder

• Allergy

• Glaucoma

• Confusion

• Memory Impairment

• Drowsiness

• Slow Heart Rate

• Tiredness

• Uncoordinated Body Movements

• Nightmare

• Cold Extremities

• How long is the duration of effect?

  The time duration this medicine has an impact is 6 to 8 hours and this duration increases to 12 hours in infants and children.

• What is the onset of action?

  This medicine starts showing its result within 30 to 40 minutes after oral dose.

• Are there any pregnancy warnings?

  This medicine is considerable for pregnant women or not is unknown till now.

• Is it habit forming?

  Its habit forming tendency is reported several times. so it is better to reduce its dosage gradually and then stop consuming.

• Are there any breast-feeding warnings?

  This medicine is may be unsafe for breastfeeding women as it can have an inadequate effect on the patient, but if necessary then first consult a doctor.

• Is It safe with alcohol?

  It is unsafe to consume alcohol while taking this medicine.

• Is it safe to drive while on this medicine?

  This medicine affects the alertness of the patient. Thus patient must avoid taking driving while taking this medicine.

• Does this affect kidney function?

  This medicine is probably safe to be used in patient with kidney disease. Availability of limited data suggests that adjustment of dose is not needed. Kindly consult your doctor before taking this medicine.

• Does this affect liver function?

  Caution must be taken while using Petril Beta 0.25 Mg/20 Mg Tablet in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking this medicine.

Below is the list of medicines, which have the same composition, strength and form as Petril Beta 0.25 Mg/20 Mg Tablet , and hence can be used as its substitute.

• Clonafit Beta Tablet

  Mankind Pharma Ltd

• Provanol Forte 0.25Mg/20Mg Tablet

  Intas Pharmaceuticals Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember. If it is time for the next scheduled dose then the missed dose can be skipped. Contact your doctor and seek advice if you there are any doubts regarding dosage.

• Are there any overdose instructions?

  Contact a doctor immediately if an overdose is suspected.

This medication is an anticonvulsant and an anti-epileptic which acts as a tranquillizer. It inhibits the synaptic transmission that occurs in the central nervous system. This medicine non-selectively blocks beta receptors sites in the heart, blood vessels, lungs and other organs. Thus pressure is lowered and blood flow in the heart and other organs is improved.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Avoid or limit the use of alcohol while you are taking this medicine. Any activity requiring a high level of mental alertness like operating heavy machinery or driving should be avoided.

• Interaction with Medicine

  • Alpha-blockers (prazosin, terazosin): Concurrent use of beta-blockers may increase risk of orthostasis.
  • Antipyrine's clearance is reduced by 30% to 40%.
  • Cimetidine increases the plasma concentration of Petril Beta 0.25 Mg/20 Mg Tablet and its pharmacodynamic effects may be increased.
  • Clonidine: Hypertensive crisis after or during withdrawal of either agent.
  • Drugs which slow AV conduction (digoxin): Effects may be additive with beta-blockers.
  • Epinephrine (including local anesthetics with epinephrine): Petril Beta 0.25 Mg/20 Mg Tablet may cause hypertension.
  • Flecainide: Pharmacological activity of both agents may be increased when used concurrently.
  • Fluoxetine may inhibit the metabolism of Petril Beta 0.25 Mg/20 Mg Tablet, resulting in cardiac toxicity.
  • Glucagon: Petril Beta 0.25 Mg/20 Mg Tablet may blunt hyperglycemic action.
  • Haloperidol: Hypotensive effects may be potentiated.
  • Hydralazine: The bioavailability propranolol (rapid release) and hydralazine may be enhanced with concurrent dosing.
  • Insulin: Petril Beta 0.25 Mg/20 Mg Tablet inhibits recovery and may cause hypertension and bradycardia following insulin-induced hypoglycemia. Also masks the tachycardia that usually accompanies insulin-induced hypoglycemia.
  • NSAIDs (ibuprofen, indomethacin, naproxen, piroxicam) may reduce the antihypertensive effects of beta-blockers.
  • Salicylates may reduce the antihypertensive effects of beta-blockers.
  • Sulfonylureas: Beta-blockers may alter response to hypoglycemic agents.
  • Verapamil or diltiazem may have synergistic or additive pharmacological effects when taken concurrently with beta-blockers; avoid concurrent I.V. use of both.

• Interaction with Disease

  • Administer cautiously in compensated heart failure and monitor for a worsening of the condition (efficacy of propranolol in CHF has not been demonstrated).
  • Avoid abrupt discontinuation in patients with a history of CAD; slowly wean while monitoring for signs and symptoms of ischemia.
  • Use caution in patient with PVD.
  • Use cautiously in diabetics because it can mask prominent hypoglycemic symptoms.
  • Can mask signs of thyrotoxicosis.
  • Can cause fetal harm when administered in pregnancy.
  • Use cautiously in hepatic dysfunction (dosage adjustment required).
  • Use care with anesthetic agents which decrease myocardial function.

• Ques : What is Petril Beta 0.25 Mg/20 Mg Tablet?

  Ans : This medication has Clonazepam and Propranolol as active elements present. It performs its action by enhancing the activity of gamma-aminobutyric acid (GABA) neurotransmitter, obstructing the action of histamine.

• Ques : What are the uses of Petril Beta 0.25 Mg/20 Mg Tablet?

  Ans : This medication is used for the treatment and prevention from conditions such as Fast heart beat, Treatment of panic disorder, Hypertension, Migraine, Panic disorder, Epilepsy, Treatment of seizure disorder, and Absence infantile spasms.

• Ques : What are the Side Effects of Petril Beta 0.25 Mg/20 Mg Tablet?

  Ans : This medication has some commonly reported side effects Depression, Fatigue, Fever, Dizziness, Emesis, Indigestion, Dull headache, Tiredness, Confusion, Shivering, Diarrhea, Abnormal eye movements, Forgetfulness, etc.

• Ques : What are the instructions for storage and disposal Petril Beta 0.25 Mg/20 Mg Tablet?

  Ans : Store this medication in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

• Ques : How long do I need to use Petril Beta 0.25 Mg/20 Mg Tablet before I see improvement of my conditions?

  Ans : This medicine takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

• Ques : What are the contraindications to Petril Beta 0.25 Mg/20 Mg Tablet?

  Ans : Contraindication to Petril Beta. In addition, this medication should not be used if you have the following conditions such as Alcohol, Cardiogenic shock, Chronic obstructive pulmonary disease, Congestive heart failure, etc.

• Ques : Is Petril Beta 0.25 Mg/20 Mg Tablet safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

• Ques : Will Petril Beta 0.25 Mg/20 Mg Tablet be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of this medication can lead to increased chances of side effects such as Fatigue, Depression, Fever, Dizziness, Emesis, Indigestion, Dull headache, Breath shortness, Confusion, etc.

• Clonazepam (Rivotril): Uses, Side Effects,Mechanism & Dosage- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 26 April 2019]. Available from:

  https://www.drugsbanks.com/clonazepam-rivotril/

• Clonazepam- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 26 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/clonazepam

• Propranolol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/propranolol

• Propranolol- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 16 May 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00571