Phenergan Syrup

Phenergan Syrup is prescribed for symptomatic treatment of various allergic conditions. It is also used as an antiemetic, to treat motion sickness, as a sedative. This medicine also employes as an analgesic adjunct for control of postoperative pain or an anesthetic adjunct.

Belonging to a group of drugs called phenothiazines, Phenergan Syrup is used to treat allergies with symptoms like a runny nose, hives, and watery eyes. Acting as an anti-histamine, it blocks the effect of histamine in the body. It is also helpful in treating motion sickness, nausea, and vomiting. It is often utilized as a sleeping aid.

If you are allergic to similar medicines like chlorpromazine, mesoridazine, fluphenazine, perphenazine, prochlorperazine, thioridazine, or trifluperazine, Phenergan Syrup is not to be used. If you suffer from medical conditions such as seizures, glaucoma, liver and heart disease, sulfite allergy, or an enlarged prostate, alert your doctor. The drug is not for children under the age of 2.

Follow all the instructions given by your doctor while taking Phenergan Syrup. It is taken before meals or at bedtime. The medicine must be measured properly using proper dosage spoons. If it is to be used for surgery, it is usually taken the night before the procedure.

Caution in breast cancer or other prolactin-dependent tumors (may elevate prolactin levels). It may alter temperature regulation or mask toxicity of other drugs due to antiemetic effects. May alter cardiac conduction - life threatening arrhythmias have occurred with therapeutic doses of phenothiazines.

This medicine may cause orthostatic hypotension; use with caution in patients at risk of hypotension or where transient hypotensive episodes would be poorly tolerated (cardiovascular disease or cerebrovascular disease).

• Allergic Disorders

• Motion Sickness

• Allergy

• Asthma

• Depression

• Coma

• Drowsiness

• Seizures

• Headache

• Tremor

• Skin Rash

• Dry Mouth

• Constipation

• Is It safe with alcohol?

  Phenergan Syrup may cause excessive drowsiness and calmness with alcohol.

• Are there any pregnancy warnings?

  Phenergan Syrup may be unsafe to use during pregnancy. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Phenergan Syrup should not be used by breastfeeding women without consulting to the doctor.

• Is it safe to drive while on this medicine?

  Caution is advised when driving or operating machinery.

• Does this affect kidney function?

  Caution to be advised in patients with impaired renal function.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

• How long is the duration of effect?

  The duration for which this medicine will remain active is about 2 - 6 hours.

• What is the onset of action?

  The effect of this medicine is initiated within 20 minutes after its administration.

• Are there any missed dose instructions?

  If you miss a dose of Phenergan Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

• Are there any overdose instructions?

  Consult your doctor in case of overdose.

Phenergan Syrup counteracts with independent histamine for binding at H1-receptor sites in places like the GI tract, uterus, bronchial muscle, and, large blood vessels. It causes symptoms of nausea to subside via anticholinergic actions and by implicating activity on the medullary chemoreceptor trigger region.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Lab Test

  Alters the flare response in intradermal allergen tests

• Interaction with Medicine

  Concomitant use of this medicine must be avoided along with the below mentioned medicines:

  • CYP2D6 enzyme substrate.
  • Benztropine (and other anticholinergics) may inhibit the therapeutic response to Phenergan Syrup and excess anticholinergic effects may occur.
  • Chloroquine may increase Phenergan Syrup concentrations.
  • Cigarette smoking may enhance the hepatic metabolism of Phenergan Syrup. Larger doses may be required compared to a nonsmoker.
  • Concurrent use of Phenergan Syrup with an antihypertensive may produce additive hypotensive effects.
  • Antihypertensive effects of guanethidine and guanadrel may be inhibited by Phenergan Syrup.
  • Concurrent use with TCA may produce increased toxicity or altered therapeutic response.
  • Phenergan Syrup may inhibit the antiparkinsonian effect of levodopa; avoid this combination.
  • Phenergan Syrup plus lithium may rarely produce neurotoxicity.
  • Barbiturates may reduce Phenergan Syrup concentrations.
  • Propranolol may increase Phenergan Syrup concentrations.
  • Sulfadoxine-pyrimethamine may increase Phenergan Syrup concentrations.
  • Phenergan Syrup and possibly other low potency antipsychotics may reverse the pressor effects of epinephrine.
  • Phenergan Syrup and CNS depressants (ethanol, narcotics) may produce additive CNS depressant effects.
  • Phenergan Syrup and trazodone may produce additive hypotensive effects.

• Interaction with Disease

  May impair physical or mental abilities; patients must be cautioned about performing tasks which require mental alertness (ie, operating machinery or driving). Effects with other sedative drugs or ethanol may be potentiated. Avoid use in Reye's syndrome. Use with caution in Parkinson's disease; hemodynamic instability; bone marrow suppression; predisposition to seizures; subcortical brain damage; and in severe cardiac, hepatic, renal, or respiratory disease.

• Ques : Is Phenergan Syrup a narcotic/opiate/pain killer?

  Ans : Promethazine, active constituent of Phenergan Syrup, is an antihistamine drug and not a narcotic/opiate/pain killer. The patient should follow the advice of the doctor regarding its use.

• Ques : Is Phenergan Syrup over the counter?

  Ans : No, this drug is only available with a doctor's prescription only.

• Ques : Can I take Phenergan Syrup for a hangover/sore throat/ nausea/stomach flu/cramps/toothache/ headache/ cough/pain?

  Ans : This medication is used for the treatment of symptoms of allergies, but not used for a hangover, sore throat, stomach flu, cramps, toothache, headache and cough. The patient should follow the advice of the doctor regarding its use.

• Ques : Can I take Phenergan Syrup with Nyquil/ codeine and ibuprofen/ Tylenol/ oxycodone/ Benadryl/ Dayquil/ Zofran/codeine and Nyquil/Xanax?

  Ans : Yes, but taking other medicines may alter the effects of Phenergan Syrup. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.

• Ques : Does Phenergan Syrup has codeine in it?

  Ans : No, it does not contain codeine in it.