Pirfenidone

Pirfenidone is an antifibrotic agent. It is used to treat mild cases of a lung disease called idiopathic pulmonary fibrosis. The exact working of this medication is not known.

On using this medication you may experience side effects such as muscle pain, sneezing, dizziness, reduced appetite, sudden weight loss, difficulty with sleeping, heartburn, acidity, change in taste, weakness, fatigue, headache, runny nose, stomach upset, diarrhoea, nausea, vomiting, skin rash and redness. If you face any allergic reactions or adverse reactions seek the help of your health care provider right away.

Before using this medication notify your doctor if: you are allergic to any of the ingredients contained within Pirfenidone, you have liver /kidney problems, you have any other allergies, you smoke, you are taking any other medications that may increase the chances of sunburn, you are pregnant or are planning to become pregnant or are nursing a baby.

The dosage for this medication should be prescribed by the doctor based on your condition. The usual dose in adults for treating Idiopathic Pulmonary Fibrosis is 267 mg orally thrice a day over a period of 1-7 days and 534 mg from days 8-14.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

• Idiopathic Pulmonary Fibrosis

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

• Nausea

• Vomiting

• Headache

• Rash

• Dizziness

• Fatigue

• Abdominal Pain

• Joint Pain

• Insomnia (Difficulty In Sleeping)

• Loss Of Appetite

• Gastro-Esophageal Reflux Disease (Gerd)

• Diarrhoea

• Weight Loss

• Upper Respiratory Tract Infection

• Dyspepsia

• Sinus Inflammation

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Fiboresp 200mg tablet may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Caution is advised when driving or operating machinery.

• Does this affect kidney function?

  Caution should be used in patients with renal impairment.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

Below is the list of medicines, which contains Pirfenidone as ingredient

• Pirfetab 200Mg Tablet

  Zydus Cadila

• Pirfenex 200mg Tablet

  Cipla Ltd

• Fibrodone 200Mg Tablet

  Lupin Ltd

• Fiboresp 200Mg Tablet

  Glenmark Pharmaceuticals Ltd

• Spiropirf 200Mg Tablet

  Koye Pharmaceuticals Pvt ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

This medication works by preventing collagen synthesis, suppresses profibrotic cytokines and reduces fibroblast multiplication. The drug results in the decrease of TGF-beta2 mRNA and TGF-beta2 protein levels as a consequence of the decline of the expression and prevention of the TGF-beta pro-protein convertase furin.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

• Pirfenidone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 15 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/pirfenidone

• Pirfenidone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 15 June 2022].Available from:

  https://go.drugbank.com/drugs/DB04951

• PIRFENIDONE tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 15 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=PIRFENIDONE