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Overview

Piroxicam

Prescription vs OTC : Prescription by Doctor required

About Piroxicam

Piroxicam is used in the treatment of swelling, pain and joint stiffness resulting from arthritis. This medication belongs to a group of drugs called NSAIDs (Nonsteroidal anti-inflammatory drugs). It works by inhibiting the production of certain substances in the body that leads to inflammation.

This medicineis helpful in the management of inflammatory disorders. Piroxicam is also prescribed as a symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Also used to treat sunburn.

Take the medication orally after consulting with your doctor. The usual dosage is 1 tablet per day. Avoid lying down immediately after taking this medication. You should take this medication with milk, food or an antacid to prevent stomach problems.

The doctor will prescribe the dose based on your medical condition and how you are responding to the treatment. It is often recommended to take the lowest possible dose to prevent various problems like stomach bleeding and other problems.

Side effects of this medication are stomach problems, drowsiness, nausea and dizziness. You should consult your doctor if these side effects become severe. Piroxicam can also raise your blood pressure. In rare cases, this drug can also result in serious liver problems.

If you see symptoms of liver damage like dark urine, nausea, vomiting, yellow eyes/skin and loss of appetite then consult a doctor immediately. You also need to take certain precautions before taking this medication. You need to inform your doctor about any allergies that you may have before starting a course of this medication.

This drug may also contain certain inactive ingredients that can cause allergic reactions in the body. You should also inform the doctor about any history of blood disorders, anemia and heart conditions before taking this medication.

It is advised to avoid driving or perform any other activity that requires alertness immediately after taking this medication. You should also try to stay off alcohol and tobacco while taking this medication as it increases the risk of stomach bleeding.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

    What are the uses of Piroxicam

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

    What are the contraindications of Piroxicam ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

    What are the side effects of Piroxicam ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

    Key highlights of Piroxicam

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 48 to 72 hours.

    • What is the onset of action?

      The effect of this medicine can be observed in 30 min to 1 hour.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for breastfeeding women.

    • Is It safe with alcohol?

      It is found to be unsafe to consume along with this medicine.

    • Is it safe to drive while on this medicine?

      This medicine might affect the consciousness of the patient, thus driving must be avoided.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. Adjustment of dose might be needed. Kindly consult your doctor.

    • Does this affect liver function?

      Caution must be taken in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

    • Are there any overdose instructions?

      A doctor should be contacted immediately if an overdose of Piroxicam is suspected. Signs and symptoms of overdose include stomach irritation, difficulty in breathing, black colored stools etc. Immediate medical attention is needed if an overdose is confirmed.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

    Where is the Piroxicam approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

    Medicines containing Piroxicam

    Below is the list of medicines, which contains Piroxicam as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

    How does this medication work?

    This medicine works as an analgesic by inhibiting prostaglandin synthesis which is essential to sensitize the afferent nerves to induces pain. It works as an anti-inflammatory by inhibiting the prostaglandins synthesis which are mediators of inflammation.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Rheumatologist before using this medicine.

      What are the interactions of Piroxicam ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        This medicine should not be consumed with alcohol. Symptoms of stomach bleeding (such as the presence of dried and coffee colored blood in cough or stools) should be reported to the doctor immediately.
      • Interaction with Lab Test

        This medicine increase the Bleeding time and as well as the chloride and sodium level in blood.
      • Interaction with Medicine

        Warfarin

        These medications may increase the risk of bleeding if taken together. Inform the doctor if you are receiving any pain medications or if you have any bleeding disorder. An alternate class of medicine should be considered based on the clinical condition.

        Corticosteroids

        Use with caution as this combination will increase the risk of gastrointestinal bleeding. Inform the doctor if you are taking either of the medicines. Consider taking alternative medicine after consulting your doctor.

        Fluoroquinolone

        These medications may increase the central nervous system stimulation and causes tremors, involuntary body movements, and seizures. Inform the doctor if you are receiving antibiotics belongs to fluoroquinolones. Consider the alternate class of medicine based on the clinical condition.

        Angiotensin converting enzyme inhibitors

        Piroxicam may alter the effect of antihypertensives, therefore should be used with caution. Inform the doctor if you are receiving antihypertensives like captopril, enalapril, benazepril. Monitoring of blood pressure is necessary. Any changes in the blood pressure should be informed to the doctor. Dose adjustments are to be made based on the clinical condition.
      • Interaction with Disease

        Asthma

        Piroxicam should not be taken if you have NSAID-sensitive asthma. Any such history should be reported to the doctor so that appropriate substitution can be done.

        Gastrointestinal Toxicity

        Piroxicam and other NSAIDs should be taken after consulting a doctor especially if the intended duration is longer than a month. Any symptom indicating ulceration and bleeding like chronic indigestion, coffee colored dry blood in stools or vomiting of blood should be reported immediately.
      • Interaction with Food

        May be administered with food to decrease GI adverse effect

      FAQs about Piroxicam

      • Ques : What is Piroxicam?

        Ans : Piroxicam is a salt which performs its action by obstructing the release of a specific chemical that is responsible for pain and swelling. Piroxicam is used to treat conditions such as Swelling, stiffness and joint pain, Osteoarthritis, Rheumatoid arthritis, Acute gout, etc.

      • Ques : What are the uses of Piroxicam?

        Ans : Piroxicam is a salt, which is used for the treatment and prevention from conditions such as Swelling, stiffness and joint pain, Osteoarthritis, Rheumatoid arthritis, Acute gout, and Postoperative pain. Apart from these, it can also be used to treat conditions like Acute musculoskeletal conditions and Juvenile idiopathic arthritis. The patient should inform the doctor about any ongoing medications and treatment before using Piroxicam to avoid undesirable effects.

      • Ques : What are the Side Effects of Piroxicam?

        Ans : Piroxicam is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of Piroxicam which are as follows: Abdominal pain, Constipation, Headache, Dizziness, Burning sensation in stomach, Excessive air or gas in the stomach, shakiness in the legs, arms, hands, or feet, Loss of strength, Restlessness, and Change in appetite. It is a list of possible side-effects which may occur due to the constituting ingredients of Piroxicam.

      • Ques : What are the instructions for storage and disposal Piroxicam?

        Ans : Piroxicam should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects. It is a prescribed medication.

      • Ques : Should I use Piroxicam empty stomach, before food or after food?

        Ans : The consumption of this medication is done orally. If you take this medication with the food, the reactions that took place in the body carry outs in a much effective manner. Your stomach might get upset if you take this medication on an empty stomach. It is advised to consult a doctor before taking Piroxicam.

      • Ques : How long do I need to use Piroxicam before I see improvement of my conditions?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking Piroxicam longer than it was prescribed, can cause an inadequate effect on the patient's condition. So please consult your doctor.

      • Ques : Is there any food or drink I need to avoid?

        Ans : There is no specific food product to avoid, under usage of this medication. It will be beneficial to keep your diet healthy and to ignore street food in order to avoid any kind of harmful bacterial intake. It is also advised to stay away from drinking and smoking to uplift your health.

      • Ques : Will Piroxicam be more effective if taken in more than the recommended dose?

        Ans : Please follow the doses of the medication, as prescribed by your doctor. If you take more than the recommended doses of Piroxicam, it may cause some side effects. It is advised to ask your doctor to re-examine your condition if the severity in the health is not reducing.

      References

      • Piroxicam-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/piroxicam

      • Piroxicam-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00554

      • PIROXICAM tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=PIROXICAM

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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