Pralidoxime

Pralidoxime belongs to the oximes family of compounds. It is used as an antidote that battles poisoning caused by organophosphates, mostly found in pesticides.

The most important function of Pralidoxime is to activate and release cholinesterase, usually near the Central Nervous System, and thus regenerating the functional enzyme that has been blocked by phosphorylation. This kind of poisoning is mostly caused by an organophosphate pesticide, or any other related compounds. The chemical reactions act as a counteragent for certain organophosphates, and turn them to a non-reacting form.

The Pralidoxime is an effectual drug in relieving critically affected paralysis of the respiratory muscles. It is also a remedy for other various intramuscular disorders, bronchospasm, and excessive salivation. The drug is mostly injected into an intramuscular site causing mild pain in the injected region.

The Pralidoxime may also have certain adverse side effects such as blurred vision, dizziness , drowsiness, high blood pressure, weakness of joints and muscles, hyperventilation, nausea and vomiting. However in case the symptoms persist or turn severe, it is wise to immediately consult a medical expert rather than discontinuing the drug dose without proper advice.

Pregnant women and nursing mothers should preferably not be subjected to this drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

• Nausea

• Muscle Weakness

• Drowsiness

• Headache

• Dizziness

• Double Vision

• Blurred Vision

• Increased Blood Pressure

• Hyperventilation

• Increased Heart Rate

• Accomodation Disturbance

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Neopam 25mg injection may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  There is no data available. Please consult doctor before consuming the drug.

• Does this affect kidney function?

  Caution should be advised in patients with renal impairment.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of Pralidoxime, please consult your doctor.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

Below is the list of medicines, which contains Pralidoxime as ingredient

• Neopam 25Mg Injection

  Troikaa Pharmaceuticals Ltd

• Aldopam 500Mg Injection

  Samarth Life Sciences Pvt Ltd

• Cbc Pam 500Mg Injection

  Chandra Bhagat Pharma Pvt Ltd

• Unipam 1Gm Injection

  Vhb Life Sciences Inc

• Clopam 1Gm Injection

  Chandra Bhagat Pharma Pvt Ltd

• Toxipam 500Mg Injection

  Bharat Serums & Vaccines Ltd

• Allpam 25mg Injection

  Lincoln Pharmaceuticals Ltd

• Neopam 500mg Injection

  Troikaa Pharmaceuticals Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.

This medication is used during organophosphate poisoning. Organophosphates like sarin block the activity of acetylcholinesterase enzyme by binding to the hydroxy component of the active site. It binds to the remaining half and removes the phosphate from the remnants of serine, thereby allowing re-activation of the enzyme.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Toxicologist before using this medicine.