Pregaba-M 75 Capsule

Pregaba-M 75 Capsule is a combination of a coenzyme form of Vitamin B12 along with GABA analog. It circulates through the bloodstream and is used to treat Peripheral neuropathy. In addition to the Vitamin B12 structure, it has an additional methyl containing metal-alkyl group.

It is one of the most important nutrients required in the human body. A lack of this vitamin can cause severe and permanent neurological damage. The medicine also treats Pernicious anaemia with weakness, numbness, tingling of fingers, etc.

This medicine is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia. It is used for the treatment of diabetic nerve pain, epilepsy, spinal cord injury, restless leg syndrome and generalised anxiety disorder.

It plays a key role in the functioning of the Brain and Nervous system and the formation of the Red Blood Cells. Also, it is responsible for the protection and regeneration of Neurons. This medicine also fights against the degenerative cell condition called Multiple sclerosis. It acts as a stress reliever for the body and mind.

Symptoms are not always prevalent in case of this medication deficiency. But sometimes many symptoms of lacking this medication can appear such as

• Anaemia
• Fatigue
• Weakness
• Lack of balance
• Indigestion
• Gastrointestinal problem
• Lack of sensation on touching
• Memory loss

• Neuropathic Pain

• Peripheral Neuropathy

• Decreased Potassium Level In Blood

• Allergy

• Leber's Disease

• Tiredness

• Dizziness

• Uncoordinated Body Movements

• Sleepiness

• Abdominal Pain

• Nausea Or Vomiting

• Skin Rash

• How long is the duration of effect?

  The effect of this tablet or capsule exists for approximately 10-12 hours after intake. However this is likely to vary.

• What is the onset of action?

  Pregaba M 75 medicine has a varying time for functioning and it depends mostly on the purpose of the medicine. Usually it takes more than 2 days to impact but sometimes may even show results of improvement within 15/16 hours of use.

• Are there any pregnancy warnings?

  Use of Pregaba-M 75 Capsule may be unsafe during pregnancy and hence it is not recommended unless absolutely necessary and there are no other alternatives that could cure the problems. It is anyhow safe to be used in oral or topical ways till the first trimester of pregnancy but not after that. A doctor should certainly be consulted to discuss the risks before taking this drug during pregnancy.

• Is it habit forming?

  No, Pregaba M 75 is not known to be habit forming among patients. People do not grow addicted to this drug, according to the survey studies.

• Are there any breast-feeding warnings?

  Use of this medicine by lactating or breast feeding women is strictly not advised. However, if the continuation of medicine becomes necessary, then breastfeeding should be stopped. Women who are breastfeeding or lactating may suffer severe adverse effects if they consume this tablet during that time. Besides, the baby could also be affected. It is always recommended to consult a doctor before using this medicine.

• Is It safe with alcohol?

  Consumption of alcohol during medication is not advisable. One should stop or limit the consumption of alcohol as the interaction of alcohol with pregaba M 75 can cause serious health issues and degrade health.

• Is it safe to drive while on this medicine?

  It is not safe to drive after the intake of this medicine as it might have sedative effects and the patient could feel drowsy, weak and strained. In fact, works which involve mental alertness should not be performed after taking this medicine.

• Does this affect kidney function?

  Even if there has been not much reports on the effect of Pregaba M 75 on kidneys, patients with kidney related problems or renal problems should consult a doctor before administering this medicine. There might be a need to change the dose in patients who already have kidney issues,and thus caution must be taken in such cases.

• Does this affect liver function?

  Pregaba M 75 is safe to be used in patients with liver related problems as this medicine has not been found to show any counteracted impacts on liver.

Below is the list of medicines, which have the same composition, strength and form as Pregaba-M 75 Capsule , and hence can be used as its substitute.

• Nuromark 750 Mcg/75 Mg Tablet

  Unimarck Healthcare Ltd

• Doloneuron PG 75mg Capsule

  Pulse Pharmaceuticals

• Dewfit Capsule

  Dew Drops Lab

• Altranerv Capsule

  Aaltramed Healthcare Ltd

• Pregard M Capsule

  Organic Laboratories

• M Strong Pg Tablet

  Lloyd Healthcare Pvt Ltd

• Odyna P 750Mcg/75Mg Capsule

  MVD Pharmaceuticals Pvt Ltd

• Vitexid P 750Mcg/75Mg Capsule

  Maneesh Pharmaceuticals Ltd

• Gabamax 750 Mcg/75 Mg Capsule

  Aristo Pharmaceuticals Pvt Ltd

• Methynxt 750Mcg/75Mg Capsule

  Hamps India Pvt Ltd

• Are there any missed dose instructions?

  Missed dose should be made up for unless the time of the next dose is near. In such cases where the next dose is due very soon, double dosage should not be taken as that may cause over consumption.

• Are there any overdose instructions?

  If symptoms like agitation, mental confusion, excessive drowsiness appear then it could possibly be because of over dosage. In that case, the intake of medicines should be immediately stopped and a doctor should be consulted to curb the symptoms.

Pregaba-M 75 Capsule acts as a cofactor for enzyme methionine synthase, which transfers methyl groups for the regeneration of methionine from homocysteine. In anemia, it increases blood cell production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes. It also binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  It is not safe to drink alcohol while taking Pregaba M 75 as it is likely to increase the drowsiness and calmness in a person. Patients may feel even sleepier if both of them are taken together. This can also cause several harmful effects on the patients.

• Interaction with Medicine

  Pregaba-M 75 Capsule shows severe side effects on reaction with some drugs. Drugs of Cholchicine like Nuforce, Cholchicindon, Goutnil, etc, Amphetamine like Evekeo, Captopril like Aceten, Angiopril react severely with Pregaba M 75 and cause acute problems in patients. Medicines that have shown to react moderately include Alogliptin (Nesina), Metformin (Exermet, Gluformin, Gluconorm, etc ) Vitamin C intakes ( Mankind Vitamin C, Becosules etc. )

• Interaction with Disease

  Patients who are suffering from any disease should always consult and discuss with a doctor regarding the risk factors involved on consumption of this tablet.

• Interaction with Food

  This medicine is not known to have any particular interactions with food and can be consumed safely with food of all types. However, if the patient is allergic to any kind of food, then that must be discussed with the doctor before taking the medicine.

• Ques : What is Pregaba-M 75 Capsule?

  Ans : Pregaba-M 75 Capsule is classified as an anti-epileptic medicine, used for the treatment of certain types of seizures. It contains Methylcobalamin and Pregabalin as active ingredients. Pregaba-M 75 Capsule works by modifying the release of certain substances released by the nerves in the brain; works in the recovery process of damaged nerve cells.

• Ques : What is the use of Pregaba-M 75 Capsule?

  Ans : Pregaba-M 75 Capsule is used for the treatment and prevention from conditions and symptoms of diseases like pain occurring in neurological disorders, nerve damage and anxiety disorder in adults. Besides these, it can also be used to treat conditions like anemia, seizures, numbness, and tingling. The patient should inform the doctor about any ongoing medications and treatment before using Pregaba-M 75 Capsule to avoid undesirable effects.

• Ques : What are the side effects of Pregaba-M 75 Capsule?

  Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of Pregaba-M 75 Capsule. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include gas, urge to vomit, irritability, muscle cramps, fatigue, and blurred vision. Apart from these, using this medicine may further lead to conditions like clumsiness, unable to sleep, memory impairment and sore throat. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

• Ques : Can Pregaba-M 75 Capsule be used for pain in neurological disorders and nerve damage pain?

  Ans : Yes, treating pain in neurological disorders and nerve damage pain are two of the many uses of Pregaba-M 75 Capsule. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

• Ques : How long do I need to use Pregaba-M 75 Capsule before I see improvement of my conditions?

  Ans : In Most of the cases the average time taken by this medication, to reach its peak effect is within 1 to 2 weeks, before noticing improvement in the condition. But the same experience is not mandatory to everyone and so, it is not a recommended time period for this medication's action. Please consult your doctor, for the time period you need to consume this medication.

• Ques : At what frequency do I need to use Pregaba-M 75 Capsule?

  Ans : Pregaba-M 75 Capsule is generally used once or twice a day, as the time interval upto which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.

• Ques : Should I use Pregaba-M 75 Capsule empty stomach, before food or after food?

  Ans : This medication is commonly taken orally from mouth and the action of salts involved in this medication, do not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

• Ques : What are the instructions for storage and disposal of Pregaba-M 75 Capsule?

  Ans : Pregaba-M 75 Capsule contains salts, which are suitable to store at room temperature and keeping this medication above or below that, can cause inadequate effect. Protect it from moisture and light. Keep this medication, away from the reach of children. It is advised to dispose the expired or unused medication, for avoiding its inadequate effect.

• Methylcobalamin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/methylcobalamin

• Pregabalin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/pregabalin

• Pregabalin: Uses, Side effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 25 April 2019]. Available from:

  https://www.drugsbanks.com/important-information-about-pregabalin/