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Overview

Pregabid Nt - 75 Tablet

Manufacturer :  Intas Pharmaceuticals Ltd
Medicine Composition :  Pregabalin, Nortriptyline
Prescription vs OTC : Prescription by Doctor not required

About Pregabid Nt - 75 Tablet

Pregabid Nt - 75 Tablet is a combination medication prescribed for the treatment of severe neuropathic pain. It is also used for the management of neuropathic disorders like diabetic peripheral neuropathy, postherpetic neuralgia, and spinal cord injury.

It works by binding to a certain region of the brain and reducing the pain signals sent out by the damaged nerves of the body. This medicine is also utilised for treating restless leg syndrome, epilepsy, shingles, seizures, fibromyalgia and generalised anxiety disorder.

This medication is not recommended for you if you are pregnant, or have an allergic reaction towards any of its ingredients. Some medicines interact with it. Inform your doctor if you are taking any of the following:

  • Angiotensin- converting enzyme inhibitors
  • Benzodiazepines or narcotic pain medicines
  • Thiazolidinedione antidiabetic agents

Ensure your doctor is informed if you have any of the following medical conditions before starting the medication if you are or have:

  • Congestive heart failure, irregular heartbeat, diabetes, bleeding problems, muscle problems, highballed pressure or low platelet count.
  • Improper kidney functioning or are on dialysis.
  • History of angioedema.
  • Pregnant, planning to be pregnant or are breastfeeding.
  • Taking any other medicines, dietary supplements or herbal preparations.
  • Mental or mood problems, suicidal thoughts, or are dealing with depression.

The dose for this medication may vary according to the age, sex, pathological conditions and other factors. The dosage can later be increased depending on efficacy and tolerability of the patient.

    What are the uses of Pregabid Nt - 75 Tablet

    • Neuropathic Pain

    • Diabetic Peripheral Neuropathy

    • Postherpetic Neuralgia

    What are the contraindications of Pregabid Nt - 75 Tablet ?

    • Hypersensitivity

    • Myocardial Infarction

    What are the side effects of Pregabid Nt - 75 Tablet ?

    Key highlights of Pregabid Nt - 75 Tablet

    • How long is the duration of effect?

      The duration of the effect of the medication lasts for about 10-12 hours on an average.

    • What is the onset of action?

      The onset of action varies from patient to patient depending on the condition for it is used and the severity of the condition.

    • Are there any pregnancy warnings?

      Pregnant women must avoid this medication, if possible, to avoid any serious damages caused to the foetus. Consume it only after consulting a doctor and if the benefits outweigh the risks involved.

    • Is it habit forming?

      It can be habit-forming in some patients and even affect their behaviour. The medication has a low abuse potential with the person depending on it for physical or psychological strength.

    • Are there any breast-feeding warnings?

      Breastfeeding women must not consume Pregabid. If there are no substitute options, make sure that you stop nursing your child.

    • Is It safe with alcohol?

      Consult your doctor before consuming alcohol.

    • Is it safe to drive while on this medicine?

      It is quite unsafe to drive while on this medication as you may experience excessive drowsiness or sleepiness. You may also experience conditions like confusion, loss of coordination or fatigue, all of which can affect your driving skills.

    • Does this affect kidney function?

      People with kidney related diseases or undergoing dialysis should discuss with your doctor regarding the safety of the medicine. The medicine can aggravate the conditions and hamper the functioning of the organ. Therefore, such patients must seek for alterations in dosage.

    • Does this affect liver function?

      If you have any liver diseases it is important that you tell your doctor about it before you start your medication. The medicine can aggravate the conditions and hamper the functioning of the organ.

    What are the substitutes for Pregabid Nt - 75 Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Pregabid Nt - 75 Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose, make sure that you consume it as soon as you remember, but not if you are close to the time of your next dose.

    • Are there any overdose instructions?

      In case of an overdose, you may experience symptoms like confusion, excessive drowsiness or agitation. You must seek the help of a doctor immediately.

    How does this medication work?

    This medication is a combination of Pregabalin and Nortriptyline, thus work through a dual mechanism of action. Primarily, it behaves as a GABA analogue and binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Secondarily, it blocks the serotonin reuptake at the neuronal membrane. Also, it inhibits the reuptake of norepinephrine and raises its concentration in the synaptic cleft.

      What are the interactions of Pregabid Nt - 75 Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        The medication can interact with alcohol and cause excessive drowsiness, sleepiness or confusion.

      • Interaction with Medicine

        Pregabid can interact with certain medicines like cimetidine, clonidine, diltiazem, fluconazole, lorazepam, nabilone, oxycodone, phenobarbitone and a few others to cause serious side effects. Therefore, it is advised that you tell your doctor about the medicines or supplements you are taking before starting the course of medication. The interaction of this medication with other medicines are discussed underneath

      • Interaction with Disease

        The medication can interact with certain allergies and kidney or liver related diseases. Therefore, it is crucial that you discuss everything about your medical history with the doctor to avoid any serious implications.

      • Interaction with Food

        It is advised that you do not consume caffeine in excess while on this medication.

      FAQs about Pregabid Nt - 75 Tablet

      • Ques : What is Pregabid nt 75 tablet?

        Ans : This medication is a combination of Pregabalin and Nortriptyline and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia.

      • Ques : What is Pregabid nt 75 tablet used for?

        Ans : This drug is used to treat Neuropathic Pain.

      • Ques : What are the side effects of Pregabid nt 75 tablet?

        Ans : Side effects include dizziness, sleepiness, constipation, etc.

      • Ques : How to manage weight gain associated with the use of Pregabid NT?

        Ans : Pregabid is a medication which can make the patient feel hungry, thereby increasing your chances of weight gain. However, avoiding weight gain is easier than losing weight. Try to have a healthy balanced diet without gaining your portion sizes.

      • Ques : How long do I need to use pregabid nt 75 tablet before I see improvement of my conditions?

        Ans : This medication should be consumed, till the complete eradication of disease. Thus it is advised to use, till the time directed by your doctor and moreover taking this medication longer than it was prescribed, can also cause inadequate effect on the patient. So please consult your doctor.

      • Ques : At what frequency do I need to use pregabid nt 75 tablet ?

        Ans : This medication is generally used twice a day. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.

      • Ques : Should I use pregabid nt 75 tablet empty stomach, before food or after food?

        Ans : This medication is commonly taken orally from mouth and the action of salts involved in this medication, do not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a the day.

      • Ques : What are the instructions for storage and disposal of pregabid nt 75 tablet?

        Ans : This medication contains salts, which are suitable to store at room temperature and keeping this medication above or below that, can cause inadequate effect. Protect it from moisture and light. Keep this medication away, from the reach of children. It is advised to dispose the expired or unused medication, for avoiding its inadequate effect.

      References

      • Pregabalin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/pregabalin

      • Nortriptyline- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/72-69-5

      • Pregabalin: Uses, Side effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 25 April 2019]. Available from:

        https://www.drugsbanks.com/important-information-about-pregabalin/

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Yuvraj Arora MongaMD-Pharmacology, MBBSSexology
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