Pregalin Nt 75Mg/10Mg Tablet

Pregaba NT Tablet is a combination medication prescribed for the treatment of severe neuropathic pain. It is also used for the management of neuropathic disorders like diabetic peripheral neuropathy, postherpetic neuralgia, and spinal cord injury.

It works by binding to a certain region of the brain and reducing the pain signals sent out by the damaged nerves of the body. This medicine is also utilised for treating restless leg syndrome, epilepsy, shingles, seizures, fibromyalgia and generalised anxiety disorder.

Pregaba NT Tab is not recommended for you if you are pregnant, or have an allergic reaction towards any of its ingredients. Some medicines interact with it. Inform your doctor if you are taking any of the following:

• Angiotensin- converting enzyme inhibitors
• Benzodiazepines or narcotic pain medicines
• Thiazolidinedione antidiabetic agents

Ensure your doctor is informed if you have any of the following medical conditions before starting the medication:

• If you have congestive heart failure, irregular heartbeat, diabetes, bleeding problems, muscle problems, highballed pressure or low platelet count.
• If you have improper kidney functioning or are on dialysis.
• If you have a history of angioedema.
• If you are pregnant, planning to be pregnant or are breastfeeding.
• If you take any other medicines, dietary supplements or herbal preparations.
• If you have mental or mood problems, suicidal thoughts, or are dealing with depression.

The dose for this medication may vary according to the age, sex, pathological conditions and other factors. The dosage can later be increased depending on efficacy and tolerability of the patient.

• Neuropathic Pain

• Diabetic Peripheral Neuropathy

• Postherpetic Neuralgia

• Allergy

• Myocardial Infarction

• Weight Gain

• Blurred Vision

• Dry Mouth

• Dizziness

• Drowsiness

• Peripheral Edema

• Nausea

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 10-12 hours.

• What is the onset of action?

  This medicine has a varying onset time depending on the intended use.

• Are there any pregnancy warnings?

  Use of this medicine during pregnancy is not recommended unless absolutely necessary.

• Is it habit forming?

  This medicine has a low abuse potential with limited physical and psychological dependence.

• Are there any breast-feeding warnings?

  Use of this medicine by breastfeeding women is not recommended.

• Is It safe with alcohol?

  Pregalin Nt 75Mg/10Mg Tablet may cause excessive drowsiness and calmness with alcohol.

• Is it safe to drive while on this medicine?

  Pregalin Nt 75Mg/10Mg Tablet may affect your alertness which may affect your ability to drive.

• Does this affect kidney function?

  Pregalin Nt 75Mg/10Mg Tablet should be used with caution in patients with kidney disease.

• Does this affect liver function?

  Pregalin Nt 75Mg/10Mg Tablet is probably safe to use in patients with liver disease.

Below is the list of medicines, which have the same composition, strength and form as Pregalin Nt 75Mg/10Mg Tablet , and hence can be used as its substitute.

• Pretyline 75Mg/10Mg Tablet

  Carise Pharmaceuticals Pvt Ltd

• Nuromark Pnt 75Mg/10Mg Tablet

  Unimarck Healthcare Ltd

• Preganza Nt Tablet

  Emcure Pharmaceuticals Ltd

• Neurotin-Nt Tablet

  Medsol India Overseas Pvt Ltd

• Gabacure Nt 75Mg/10Mg Tablet

  HBC Lifesciences Pvt Ltd

• Pregalift Nt 75 Mg/10 Mg Tablet

  Linux Laboratories

• Megabid Nt 75Mg/10Mg Tablet

  Ordain Health Care Global Pvt Ltd

• Pregamax Nt 75Mg/10Mg Tablet

  Winmark Pharmaceuticals Pvt Ltd

• NERVILAX NT 75MG/10MG TABLET

  Saffron Therapeutics Pvt Ltd

• Zylin Nt 75 Mg/10 Mg Tablet

  Zydus Cadila

• Missed Dose instructions

  Take the missed dose as soon as you remember.

• Are there any overdose instructions?

  Contact your doctor immediately if an overdose is suspected.

This medication is a combination of Pregabalin and Nortriptyline, thus work through a dual mechanism of action. Primarily, it behaves as a GABA analogue and binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Secondarily, it blocks the serotonin reuptake at the neuronal membrane. Also, it inhibits the reuptake of norepinephrine and raises its concentration in the synaptic cleft.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Avoid or limit the use of alcohol while taking this medicine. One should refrain from operating heavy machinery or performing works that require a high level of mental alertness.

• Interaction with Lab Test

  Information not available.

• Interaction with Medicine

  Do not use this tablet in combination with Lorazepam, Pioglitazone, Ramipril and Oxycodone.

• Interaction with Food

  Information not available.

• Interaction with Disease

  Patients who suffer from Angioedema should exercise caution while taking this tablet.

• Ques : What is Pregalin Nt 75Mg/10Mg Tablet?

  Ans : This medication is a combination of Pregabalin and Nortriptyline and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia.

• Ques : What are the uses of Pregalin Nt 75Mg/10Mg Tablet?

  Ans : Pregalin nt 75 mg 10 mg is used for the treatment and prevention from conditions and symptoms of diseases like anxiety disorders and nerve damage.

• Ques : What are the Side Effects of Pregalin Nt 75Mg/10Mg Tablet?

  Ans : Nausea, sore throat, memory impairment, blurred vision, muscle cramps, exhaustion, insomnia and fatigue are possible side effects.

• Ques : What are the instructions for storage and disposal Pregalin Nt 75Mg/10Mg Tablet?

  Ans : Pregalin 75 mg 10 mg tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : Should I use Pregalin Nt 75Mg/10Mg Tablet empty stomach, before food or after food?

  Ans : The onset of action of this medication will not alter in any way whether on taking it pre-meal or post-meal.

• Ques : How long do I need to use Pregalin Nt 75Mg/10Mg Tablet before I see improvement of my conditions?

  Ans : Generally, the time period to use this medication is around 1 week to 3 months to make an improvement in the condition.

• Ques : Is there any food or drink I need to avoid?

  Ans : The diet should be normal, there is nothing as such to avoid.

• Ques : Will Pregalin Nt 75Mg/10Mg Tablet be more effective if taken in more than the recommended dose?

  Ans : Excess usage of this medication can trigger side effects.

• Nortriptyline- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/pregabalin

• Pregabalin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/nortriptyline

• Nortriptyline 10 mg Film-coated Tablets [Internet]. medicines.org.uk 2019 [Cited 23 January 2020]. Available from:

  https://www.medicines.org.uk/emc/medicine/32962