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Overview

Prolustar Depo. 500 MG Injection

Manufacturer :  Cadila Pharmaceuticals Ltd
Medicine Composition :  Hydroxyprogesterone
Prescription vs OTC : Prescription by Doctor required

About Prolustar Depo. 500 MG Injection

Prolustar Depo. 500 MG Injection is a synthetic prescription medication given to pregnant women. It prevents the chances of an early delivery. This injection is given to women after the first trimester. This is a hormone medication that belongs to a category of drugs known as progestin.

This medicine is also used for the treatment of amenorrhea, abnormal uterine bleeding, endometriosis and uterine carcinoma. It needs to be administered into the muscles by trained hands only.

Do not use this injection If you have or are:

  • Allergic to any medicine, foods, substances or any of the ingredients contained within this injection.
  • Taking any prescriptive or non-prescriptive drugs, herbal, vitamins or dietary supplements.
  • Diabetes or high blood sugar.
  • Heart, liver or kidney problems.
  • Vaginal bleeding.
  • Breastfeeding a baby.
  • History of -
    • asthma or depression.
    • Epilepsy or any other kind of seizures.
    • Hormone-sensitive cancers.

The common side effects associated with Prolustar Depo. 500 MG Injection are swelling, itching, nausea, tiredness, dizziness, fever, skin eruptions and pain at the site of injection. If any severe reactions arise seek the help of your health care provider as soon as possible.

Probable allergic reacions are redness, difficulty in breathing, severe swelling of the face, lips, mouth, throat, hands, ankles or feet, signs of depression and coughing up blood.

Prolustar Depo. 500 MG Injection must be used with caution in patients with asthma, seizure disorders, migraine, cardiac or renal impairment, history of mental depression. Use of any progestin during the first 4 months of pregnancy is not recommended. And patients must be observed closely for signs and symptoms of thrombotic disorders.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    What are the uses of Prolustar Depo. 500 MG Injection

    • Premature Labor

    • Menstrual Abnormalities

    • Amenorrhea

    • Abnormal Uterine Bleeding

    • Endometriosis

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    What are the contraindications of Prolustar Depo. 500 MG Injection ?

    • Allergy

    • Abnormal Vaginal Bleeding

    • Liver Disease

    • Breast / Uterine Cancer

    • Thrombophlebitis

    • Cerebral Hemorrhage

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    What are the side effects of Prolustar Depo. 500 MG Injection ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    Key highlights of Prolustar Depo. 500 MG Injection

    • How long is the duration of effect?

      The time duration for which this medicine remains effective in the body is 1-2 weeks.

    • What is the onset of action?

      The time taken for this medicine to show it's effect is subject to vary from one person to another. It also varies based on the intended use and levels of other sex hormones in the body.

    • Are there any pregnancy warnings?

      This medicine is not recommended for use by pregnant women unless absolutely necessary and the benefits outweigh the risks associated with use. Consult your doctor before using this medicine.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for use by breastfeeding women unless necessary. Consult your doctor before using this medicine.

    • Is It safe with alcohol?

      The effect after the concomitant consumption of alcohol and this medicine is unknown. Kindly consult your doctor.

    • Is it safe to drive while on this medicine?

      This medicine is usually found to be safe.

    • Does this affect kidney function?

      Limited information is available regarding its use in patient with kidney disease. Kindly consult your doctor before taking this medicine.

    • Does this affect liver function?

      Caution must be taken in patients with hepatic impairment. Adjustment of dose might be needed. Kindly consult your doctor before taking this medicine.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    What are the substitutes for Prolustar Depo. 500 MG Injection ?

    Below is the list of medicines, which have the same composition, strength and form as Prolustar Depo. 500 MG Injection , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      Contact your doctor for further instructions if you miss a scheduled dose of this medicine.

    • Are there any overdose instructions?

      Contact a doctor if an overdose with this medicine is suspected.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    Where is the Prolustar Depo. 500 MG Injection approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    How does this medication work?

    This medication works by stimulating the actions of the luteal phase and causes changes in the uterus and vagina. It also affects the uterus and prevents contractions caused due to oxytocin.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

      What are the interactions of Prolustar Depo. 500 MG Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Thyroid function test

        Report the use of hydroxyprogesterone to the doctor before undergoing a thyroid function test. This medicine can interfere with the test and give a false positive result.
      • Interaction with Medicine

        Carbamazepine

        Report the use of either of the medicine to the doctor. You may require a dose adjustment or more frequent monitoring to ensure the safe use of these medicines together. Alternate means of birth control should be discussed with your doctor while using carbamazepine. Do not stop the use of any medication without consulting your doctor.

        Ketoconazole

        Report the use of either of the medicines to the doctor. You may need a dose adjustment and frequent monitoring to safely use these medicines together. Report any instances of nausea, vomiting, or vaginal bleeding to the doctor on priority while using these medicines.

        Warfarin

        Use of this medicine can reduce the blood level and effect of warfarin. You may a need a dose adjustment and more frequent clinical monitoring to safely use these medicines together

        Cyclosporine

        Use of this medicine may reduce or diminish the effect of cyclosporine. You may need a dose adjustment and more frequent monitoring to safely use these medicines. Do not stop the use of any medicine without consulting your doctor.

        Insulin

        Report the use of insulin or any other anti-diabetic medicine to the doctor before receiving hydroxyprogesterone. You may need an adjusted dose of the antidiabetic medicine and more frequent monitoring of blood glucose level in such cases.

        Paracetamol

        Use of this medicine may reduce or diminish the effect of paracetamol. You may need a dose adjustment and more frequent monitoring to safely use these medicines. Do not stop the use of any medicine without consulting your doctor.
      • Interaction with Disease

        Breast Cancer

        Use of this medicine is not recommended for patients having an active case of breast cancer or are suspected of having it. Report all such instance including occurrence in the past to the doctor so that an informed decision can be taken in regards to the future treatment plan.

        Liver Disease

        Use of this medicine is not recommended if the patient has a liver disease or the normal liver function is impaired.

        Thromboembolism

        Use of this medicine is not recommended in patients having a clotting disorder in which the formed clot moves from one place and lodges in another place.

        Depression

        This medicine should be used with caution in patients having episodes of depression or having a history of depression especially when estrogen is also administered in combination. The drug should be discontinued if the depression recurs and is serious.

        Retinal Thrombosis

        Use of this medicine can sometimes cause a loss of vision by blocking the flow of blood from the retina to the heart. Hence caution should be exercised while using it and any abnormality in vision should be reported to the doctor.
      • Interaction with Food

        Information not available.

      FAQs about Prolustar Depo. 500 MG Injection

      • Ques : What is Prolustar Depo. 500 MG Injection? What are its uses?

        Ans : Prolustar Depo. 500 MG Injection is progesterone (a type of female sex hormone). It helps to lower the risk for a woman to have a premature baby (early birth). It is generally taken to lower the risk of a premature baby for a second time.

      • Ques : How should I use Prolustar Depo. 500 MG Injection?

        Ans : Prolustar Depo. 500 MG Injection is given as an injection, by a doctor or trained nurse.

      • Ques : In what amount of dosage should I consume Prolustar Depo. 500 MG Injection?

        Ans : Consult your doctor for the dosage. It depends on the medical condition of the patient.

      • Ques : What if the dose is skipped from the prescribed schedule of Prolustar Depo. 500 MG Injection?

        Ans : You should make sure not to miss any dose. Nevertheless, if it is missed, consult the doctor as soon as possible.

      • Ques : Are there any side effects of Prolustar Depo. 500 MG Injection?

        Ans : Some of the common side effects could be Nausea, itching, diarrhea, weight gain, weight loss, insomnia etc. If any of these are seen, one must consult a doctor.

      • Ques : Is Prolustar Depo. 500 MG Injection safe for pregnant women?

        Ans : Prolustar Depo. 500 MG Injection is not recommended for use by pregnant women unless absolutely necessary and the benefits outweigh the risks associated with use. You should consult with your doctor before taking any.

      • Ques : Can I get addicted to Prolustar Depo. 500 MG Injection?

        Ans : No such case of addiction or habit forming has been seen till now.

      • Ques : Is there any risk involved in consuming Prolustar Depo. 500 MG Injection while I have to drive?

        Ans : This medicine is safe and no risk has been detected till now.

      • Ques : I breastfeed my baby. Is Prolustar Depo. 500 MG Injection safe for me?

        Ans : You should consult your doctor before.

      • Ques : Can I take Prolustar Depo. 500 MG Injection if I consume alcohol?

        Ans : The reaction with the alcohol is unknown yet. You must consult your doctor.

      References

      • Hydroxyprogesterone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/hydroxyprogesterone

      • Hydroxyprogesterone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

        https://go.drugbank.com/drugs/DB14570

      • HYDROXYPROGESTERONE injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=HYDROXYPROGESTERONE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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