Pyrazinamide

Pyrazinamide is an anti-tubercular medicine, which is used alongside other medicines to treat tuberculosis. It also prevents the infection from spreading. If you notice some unwanted effects like a fever, tenderness in the abdomen, jaundice, nausea, vomiting or lack of appetite inform your doctor immediately.

This medicine is not recommended during pregnancy or breastfeeding unless absolutely necessary. Consult your doctor about the potential risks and benefits before starting your treatment with this medicine.

If you suffer from the medical conditions mentioned here, inform your doctor so extra care can be taken during the treatment:

• pregnant or breast-feeding.
• kidney or liver problems, alcoholism, acute gout, diabetes or porphyria.
• If you are taking any other medicines including those which are available without a prescription as well as herbal and complementary medicines.
• Allergic to any medicine.

This medicine will be prescribed to you and you will be asked to take it three times a week during the first two months of your treatment under the supervision of a healthcare provider. Taking the tablets regularly and on time is very important.

It is also important to complete the course of treatment so that there are no chances of the infection to come back. The effect of this medicine can be observed within the first 2 hours of taking it and lasts for an average duration of 27 to 30 hours.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

• Tuberculosis

  This medication is used in the treatment of tuberculosis which is a lung disease caused by Mycobacterium tuberculosis.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

• Allergy

  Not recommended in patients with known allergy to this medication.

• Severe Liver Impairment

  Not recommended in the patients with severe liver impairment.

• Acute Gout

  Not recommended in patients with increased uric acid levels or acute gout.

• Porphyria

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

• Joint Pain

• Loss Of Appetite

• Unusual Tiredness And Weakness

• Yellow Colored Eyes Or Skin

• Itching

• Skin Rash

• Anorexia

• Flushing

• Pruritus

• Urticaria

• Photosensitivity

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 27 to 30 hours.

• What is the onset of action?

  The effect of this medicine can be observed in 2 hours.

• Are there any pregnancy warnings?

  This medicine is not recommended for use during pregnancy unless absolutely necessary.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is excreted in breast milk. It is recommended for breastfeeding women only if clearly needed.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

• Missed Dose instructions

  If you miss a dose of medication, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

Below is the list of medicines, which contains Pyrazinamide as ingredient

• Forecox -150 Tablet

  Macleods Pharmaceuticals Pvt Ltd

• Koxymide 450 MG Tablet

  Lark Laboratories Ltd

• Pyzina 1000 MG Tablet

  Lupin Ltd

• Pyra 1200 MG Tablet

  Maneesh Pharmaceuticals Ltd

• Vicox Ez Tablet

  Shrinivas Gujarat Laboratories Pvt Ltd

• Macrozide 750 MG Tablet

  Macleods Pharmaceuticals Pvt.Ltd

• Akurit-4 Tablet

  Lupin Ltd

• Pyzina 300 MG Tablet

  Lupin Ltd

• Macrozide 1000 MG Tablet

  Macleods Pharmaceuticals Pvt.Ltd

• Actizid 1500 MG Tablet

  Overseas Healthcare Pvt Ltd.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

This medicine belongs to an antitubercular class of drugs. It works by inhibiting the growth of the organism by decreasing the pH inside the cell by converting it into an active metabolite called pyrazinoic acid in the presence of pyrazinamidase.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Medicine

  Methotrexate

  These medicines may increase the risk of liver injury. Inform the doctor if you are receiving these medicines. The baseline of liver function tests should be obtained before starting the treatment. Any signs and symptoms of elevated liver enzymes, yellow colored eyes, and skin, dark urine should be reported to the doctor.

  Cholera Vaccine

  If you have taken this medication, then it is advisable to wait for 14 days before taking the Cholera vaccine. Usage of other antibiotics and vaccines should be reported to the doctor.

• Interaction with Disease

  Gout

  This medicine is not recommended in patients with gout. Inform the doctor about your medical condition. Serum uric acid levels should be monitored carefully. Discontinue the treatment if the symptoms persist.

• Interaction with Food

  Food

  Information not available.

• Ques : What is Pyrazinamide?

  Ans : is an anti-tuberculosis medicine which is used alongside other medicines to treat tuberculosis.

• Ques : How long do I need to use Pyrazinamide before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : At what frequency do I need to use Pyrazinamide?

  Ans : This medication will be prescribed to you and you will be asked to take it three times a week, during the first two months of your treatment

• Ques : Should I use Pyrazinamide empty stomach, before food or after food?

  Ans : This medication should be taken after food in a prescribed dosage.

• Ques : What are the instructions for the storage and disposal of Pyrazinamide?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Pyrazinamide- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 11 December 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/pyrazinamide

• Pyrazinamide- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 11 December 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00339

• Zinamide 500mg Tablets- EMC [Internet] medicines.org.uk. 2015 [Cited 11 December 2019]. Available from:

  https://www.medicines.org.uk/emc/product/5273/smpc