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Overview

Pyreflam 400 Mg/325 Mg Tablet

Manufacturer :  Jawa Pharmaceuticals Pvt Ltd
Medicine Composition :  Ibuprofen, Paracetamol
Prescription vs OTC : Prescription by Doctor required

About Pyreflam 400 Mg/325 Mg Tablet

Pyreflam 400 Mg/325 Mg Tablet treats inflammations as well as pain. This medicine is a combination of two non-steroidal anti-inflammatory drugs (NSAID), viz. Ibuprofen and Paracetamol. NSAIDs controls hormones in the body which cause pain and inflammation.

It thus offers relief from several problems like toothache, headache, arthritis, pain in the back, other types of small injuries and menstrual cramps. This medication is suitable for adults as well as children who are 6 months and above.

Ensure that you do not take Pyreflam 400 Mg/325 Mg Tablet if:

  • You have heart disease and are at a risk of suffering from a stroke or heart attack.
  • You have recently had a bypass operation.
  • You are allergic to any substance that is present in Pyreflam 400 Mg/325 Mg Tablet.

If you have health problems like asthma, fluid retention, kidney issues, frequent development of ulcers and bleeding, ask you medical practitioner if you can take Pyreflam 400 Mg/325 Mg Tablet.

This medicine should not be taken during the last trimester of pregnancy as it has been found that it can harm the fetus. Research has not revealed if the drug is harmful to infants who are still breastfeeding. In this case, it is best that you take your doctor’s advice.

Get in touch with your health care provider as soon as possible if you develop some of these serious side effects like pain in the stomach, indigestion, problems with breathing, weight gain, itchy skin, feeling excessively tired and weak, problems with urination and bowel movements, development of acid in the stomach etc.

    What are the uses of Pyreflam 400 Mg/325 Mg Tablet

    • Fever And Pain

    • Headache

    • Menstrual Cramps

    • Pain In Muscles

    • Joint Pain

    What are the contraindications of Pyreflam 400 Mg/325 Mg Tablet ?

    What are the side effects of Pyreflam 400 Mg/325 Mg Tablet ?

    • Acid Or Sour Stomach

    • Heartburn

    • Nausea Or Vomiting

    • Abdominal Discomfort

    • Decreased Urine Output

    • Yellow Colored Eyes Or Skin

    • Skin Rash

    • Ringing Or Buzzing In The Ears

    • Nervousness

    • Loss Of Appetite

    Key highlights of Pyreflam 400 Mg/325 Mg Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 4 to 6 hours.

    • What is the onset of action?

      The effect of this medicine can be observed in 30 to 60 minutes.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is known to excreted through breast milk in small amounts. It is recommended in breastfeeding women.

    What are the substitutes for Pyreflam 400 Mg/325 Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Pyreflam 400 Mg/325 Mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for the next dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    How does this medication work?

    Belonging to the class of NSAID, this medication works by inhibiting the enzyme cyclo-oxygenase I and II. This leads to a decrease in the synthesis of prostaglandins that regulate fever, inflammation, pain and swelling.

      What are the interactions of Pyreflam 400 Mg/325 Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Alcohol

        This medicine should not be consumed with alcohol. Symptoms of stomach bleeding (such as the presence of dried and coffee colored blood in cough or stools) should be reported to the doctor immediately.
      • Interaction with Lab Test

        5-HIAA Urine Test

        You may get a false-positive result for this test if you take this medicine.
      • Interaction with Medicine

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        One must take caution while taking this medicine. This medication may interact with other medication like Ketoconazole, Metformin, Anti-hypertensives, Methotrexate, Corticosteroids, Aspirin if administered concomitantly.
      • Interaction with Disease

        Asthma

        Pyreflam 400 Mg/325 Mg Tablet should not be taken if you have NSAID-sensitive asthma. Any such history should be reported to the doctor so that appropriate substitution can be done.

        Fluid Retention And Edema

        Pyreflam 400 Mg/325 Mg Tablet should be taken only after consulting a doctor. Monitoring of blood pressure and heart conditions is necessary on a regular level during the course of therapy.

        Skin Rash

        Pyreflam 400 Mg/325 Mg Tablet can cause these fatal skin allergies without any warnings. Signs and symptoms like rashes, hives, fever or other allergic symptoms should be reported without any delay. This condition requires immediate medical intervention.
      • Interaction with Food

        Food

        Information not available.

      FAQs about Pyreflam 400 Mg/325 Mg Tablet

      • Ques : What is Pyreflam 400 Mg/325 Mg Tablet?

        Ans : This medication is a combination of two NSAIDs, viz Ibuprofen and Paracetamol. These two controls the hormone responsible for the cause of pain and inflammation in the body. Thus provides relief from several problems like -

        • toothache,
        • headache,
        • arthritis,
        • pain in the back,
        • other types of small injuries and
        • menstrual cramps.

      • Ques : How long do I need to use Pyreflam 400 Mg/325 Mg Tablet before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Pyreflam 400 Mg/325 Mg Tablet?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Pyreflam 400 Mg/325 Mg Tablet empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Pyreflam 400 Mg/325 Mg Tablet?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Acetaminophen mixture with ibuprofen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 March 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ibuprofen%20%252F%20acetaminophen

      • Ibuprofen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 March 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ibuprofen

      • Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 March 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/paracetamol

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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