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Overview

Rabonik Plus Capsule SR

Manufacturer :  Eris Life Sciences Pvt Ltd
Medicine Composition :  Levosulpiride, Rabeprazole
Prescription vs OTC : Prescription by Doctor not required

About Rabonik Plus Capsule SR

Rabonik Plus Capsule SR is a combination medication, primarily used for treating ulcerative GERD. It is also prescribed for erosive healing, maintenance of ulcerative GERD, duodenal ulcers, irritable bowel syndrome and chronic gastritis. Recently, it has also come to be used in the treatment of hypersecretory conditions that include Zollinger-Ellison syndrome.

On using Rabonik Plus Capsule SR the associated side effects that you may suffer from are disorientation, delirium, the elevation of thyroid-stimulating hormone (TSH), rhabdomyolysis, bullous, erythema multiforme, drug-induced diarrhoea, twitching, tremor, weight gain or akathisia.

In certain severe cases, you may experience jaundice, interstitial pneumonia, tardive dyskinesia, gynecomastia (a disorder of the endocrine system where there is an enlargement of the male breast size). In the latter case it will be necessary for you to seek medical attention.

Before using this medication it is advised that you consult your doctor and tell him/her if you had/have or are:

  • Pregnant, or are planning to become pregnant.
  • Nursing a baby
  • Taking any prescriptive or over the counter drugs, herbals medications or dietary supplements.
  • A recent surgery or are scheduled for one in the near future.
  • Pheochromocytoma or gastrointestinal perforation.
  • A history of cancer-related disease.
  • A history of epilepsy or any other kind of seizures.
  • Allergic to any medicine, food or substance.

The dosage of this medication will be as prescribed by your doctor as per the severity of your condition, your age, gender and overall medical history. But commonly a dose of 25 mg of this medicine is prescribed which needs to be taken three times in a day. Results may start to show within an hour or two of using. In case of drug overdose notify your physician right away.

    What are the uses of Rabonik Plus Capsule SR

    What are the contraindications of Rabonik Plus Capsule SR ?

    What are the side effects of Rabonik Plus Capsule SR ?

    • Breast Tenderness

    • Gynecomastia

    • Weight Gain

    • Unusual Tiredness And Weakness

    • Decrease In Libido

    • Fever

    • Excessive Sweating

    Key highlights of Rabonik Plus Capsule SR

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 5-8 hours upon oral administration.

    • What is the onset of action?

      The peak effect of this medication can be observed after 1-3 hours of administration.

    • Are there any pregnancy warnings?

      This medication is not recommended for use in pregnant women owing to the risk of abnormalities in the fetus. Alternate means of blood sugar control like insulin therapy should be considered during pregnancy.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medication is not recommended for use in breastfeeding women owing to the risk of adverse effects on the baby. Alternate means of blood sugar control like insulin therapy should be considered in such cases. If it becomes absolutely necessary to take this medicine, then breastfeeding should be discontinued.

    • Is it safe to drive while on this medicine?

      This medicine affects the consciousness of the patient, thus driving must be avoided while taking this medicine.

    • Is It safe with alcohol?

      It is found to be unsafe to consume alcohol while taking this medicine.

    • Does this affect kidney function?

      Only limited information is available regarding its use in patients with kidney disease. Kindly consult your doctor before taking it.

    • Does this affect liver function?

      Caution must be taken in patients with liver disease. Adjustment of dose is needed. Kindly consult your doctor before taking this medicine.

    What are the substitutes for Rabonik Plus Capsule SR ?

    Below is the list of medicines, which have the same composition, strength and form as Rabonik Plus Capsule SR , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.

    • Are there any overdose instructions?

      Contact a doctor immediately if an overdose is suspected.

    How does this medication work?

    This medicine is a combination of Levosulpiride and Rabeprazole. These two belongs to neuroleptic and PPI class respectively. Thus this medicine works via the dual mechanism.

    Firstly, it works by selectively binding to dopamine receptors in the brain and the periphery. This action results in an increased tone of muscles in the gastrointestinal tract. Secondly, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

      What are the interactions of Rabonik Plus Capsule SR ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Avoid using alcohol while taking this medicine. Symptoms such as prolonged weakness and muscle pain, lack of sleep, breathing difficulties after alcohol intake should be reported to the doctor immediately.
      • Interaction with Lab Test

        Report the use of this medicine before undergoing a laboratory test to determine the levels of the hormone prolactin in the body. This medicine can interfere with the test and yield false positive results.
      • Interaction with Medicine

        Iodinated Contrast Media

        Discontinue the usage of Rabeprazole at least 48 hours prior to the intake of Iodinated Contrast media. Inform the doctor about Metformin use so that it can be temporarily discontinued.

        Gatifloxacin

        Report the usage of either of the medicine to the doctor. Use of this medication is not recommended along with Gatifloxacin and suitable alternates should be used instead.

        Amlodipine

        Report the use of either of the medication to the doctor as dose adjustment and safety monitoring may be required.

        Aloe Vera

        Consult your doctor for use of aloe vera while taking Rabeprazole. Suitable dose adjustments and safety monitoring may be required if the intended use is for a long duration.

        Estradiol

        Consult your doctor if you are planning to take Estradiol while taking Rabeprazole. Dose adjustment might be required in such cases. It is advised to consult your doctor before starting or stopping any medication while taking metformin.
      • Interaction with Disease

        Lactic Acidosis

        You should report the incidence of conditions like kidney impairment, heart disease, severe diarrhea, septicemia to the doctor before taking Rabeprazole. Supervised dosing and monitoring of blood sugar levels might be required in such cases. Any signs and symptoms indicative of the above-mentioned conditions should be reported immediately.

        Vitamin B12 Deficiency

        Inform the doctor about incidences of anemia or Vitamin B12 deficiency so that suitable Vitamin supplements can be prescribed if needed.
      • Interaction with Food

        Information not available.

      FAQs about Rabonik Plus Capsule SR

      • Ques : What is Rabonik Plus Capsule SR?

        Ans : This medicine is a combination of levosulpiride and rabeprazole. It is primarily used for the treatment of Gastroesophageal reflux disease and irritable bowel syndrome.

      • Ques : What are the uses of Rabonik Plus Capsule SR?

        Ans : It is prescribed for treating the following-

        • Healing of erosive or ulcerative gastro-oesophageal reflux disease (GERD)
        • Maintenance of healing of erosive or ulcerative GERD
        • Healing of duodenal ulcers
        • Treatment of pathological hypersecretory conditions, including Zollinger- Ellison syndrome
        • Irritable bowel syndrome
        • Chronic gastritis

      • Ques : What are the Side Effects of Rabonik Plus Capsule SR?

        Ans : This medication has many common side effects such as Nausea, Stomach pain, Diarrhea, Flatulence, Constipation, Headache, Dizziness, Weakness, Sleepiness, Flu-like symptoms. In case of patients having any of the side effects or issues like allergic reactions or skin rashes. It is advised to stop the consumption of this medicine and contact to doctor as soon as possible.

      • Ques : What are the instructions for storage and disposal Rabonik Plus Capsule SR?

        Ans : This medication should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      References

      • Levosulpiride- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/levosulpiride

      • Rabeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/117976-89-3

      • New Drugs Approved by CDSCO, Central Drugs Standard Control Organisation, Government of India [Internet]. cdscoonline.gov.in [Cited 23 January 2020]. Available from:

        https://cdscoonline.gov.in/CDSCO/Drugs

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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