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Overview

Reclimet Tablet

Banned
Manufacturer :  Dr Reddy s Laboratories Ltd
Medicine Composition :  Gliclazide, Metformin
Prescription vs OTC : Prescription by Doctor not required

About Reclimet Tablet

Gluconorm-G 1 Tablet is a drug that treats patients suffering from type 2 Diabetes. This medication is used to control diabetes; it is not a cure. This medicine is a combination of two antidiabetic drugs viz, Gliclazide and Metformin. These drugs belong to sulfonylurea and biguanide antidiabetic medicine class. And works by helping the pancreas in releasing insulin.

Reclimet Tablet is used concomitantly in combination as alone not either one result in adequate glycemic control. Administration of oral antidiabetic drugs has been reported to be associated with increased cardiovascular mortality as compared to treatment with diet alone or diet plus insulin.

This tablet reduces the blood sugar level. Any form of allergy must be discussed with the doctor. Consult your doctor if you have history of kidney or liver diseases. Hypoglycemia has not been observed with ingestions of up to 85 g of metformin, although lactic acidosis has occurred in such circumstances.

The active constituents are dialyzable with a clearance of up to 170 mL/minute; hemodialysis may be useful for removal of accumulated drug from patients in whom metformin overdosage is suspected

This combination is given to the patients, if patients have not responded to 4 weeks of the maximum dose of metformin monotherapy, consideration to a gradual addition of an oral sulfonylurea while continuing metformin at the maximum dose, even if prior primary or secondary failure to a sulfonylurea has occurred.

This medication makes the skin much more sensitive to the sun. Hence, if you are using this medication, use sunscreen to avoid skin problems. Limit the intake of alcohol during medication. Inform your doctor if you are using any prescribed drugs or diet supplement.

Reclimet Tablet shouldn’t be used by pregnant women. If you had a surgery recently, it is advisable not to take this medicine. The starting dose for this tablet is a 1 mg tablet once every day. Gluconorm-G 1 Tablet should be stored at a temperature between 20 to 25 degree celsius. Keep it away from heat, moisture and direct sunlight. Keep the drug away from the reach of the children and pets.

The initial and maintenance dosing should be conservative, due to the potential for decreased renal function. Generally, elderly patients should not be titrated to the maximum dose of metformin. Maintain regular dietary intake and exercise routine and always carry a quick source of sugar with you. You may experience side effects during first weeks of therapy (headache, nausea); consult prescriber if these persist.

    What are the uses of Reclimet Tablet

    • Type 2 Diabetes Mellitus

    What are the contraindications of Reclimet Tablet ?

    • Allergy

    • Diabetic Ketoacidosis

    • Impaired Kidney Function

    What are the side effects of Reclimet Tablet ?

    Key highlights of Reclimet Tablet

    • How long is the duration of effect?

      The effect of this medication lasts for an average duration of about 24 hours.

    • What is the onset of action?

      The top effect of this tablet can be observed within 4-6 hours after administration.

    • Are there any pregnancy warnings?

      Pregnant women must consult doctor before using this medication.

    • Is it habit forming?

      No habit forming tendencies were reported for this medication.

    • Are there any breast-feeding warnings?

      This medication is not recommended for women who are breastfeeding. Consult your doctor before consuming this medicine.

    • Is It safe with alcohol?

      It is unsafe to consume alcohol while taking this medicine. Kindly consult your doctor before taking it.

    • Is it safe to drive while on this medicine?

      This medicine might affect the patients ability to drive . Patient must avoid driving while taking this medicines.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. The plasma and blood half-life of metformin is prolonged and the renal clearance is decreased in proportion to the decrease in creatinine clearance. Metformin is contraindicated in the presence of renal dysfunction defined as a serum creatinine >1.5 mg/dL in males or >1.4 mg/dL in females or an abnormal creatinine clearance. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

    • Does this affect liver function?

      Caution must be taken in patients with liver disease. No studies have been conducted, however, metformin should be avoided because the presence of liver disease is a risk factor for the development of lactic acidosis during metformin therapy. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

    What are the substitutes for Reclimet Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Reclimet Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose can be taken as soon as you remember. If it is time for the next dosage then the missed dose can be skipped.

    • Are there any overdose instructions?

      Consult your doctor in case of overdose.

    How does this medication work?

    It belongs to the class sulfonylureas and works by lowering the blood glucose levels by stimulating the release of insulin from pancreatic beta cells. The drug also decreases glucose production in the liver, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing bodies glucose uptake and utilization.

      What are the interactions of Reclimet Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Incidence of lactic acidosis may be increased; avoid or limit use.
      • Interaction with Medicine

        • Decreased effect: Drugs which tend to produce hyperglycemia (eg, diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, isoniazid) may lead to a loss of glycemic control.
        • Increased effect: Furosemide increased the metformin plasma and blood Cmax without altering metformin renal clearance in a single dose study.
        • Increased toxicity: Cationic drugs (eg, amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, and vancomycin) which are eliminated by renal tubular secretion could have the potential for interaction with metformin by competing for common renal tubular transport systems.
        • Cimetidine increases (by 60%) peak metformin plasma and whole blood concentrations.
      • Interaction with Food

        • Food: Food decreases the extent and slightly delays the absorption. Drug may cause GI upset; take with food to decrease GI upset.
        • Glucose: Decreases blood glucose concentration. Hypoglycemia does not usually occur unless a patient is predisposed. Monitor blood glucose concentration. Exercise caution with administration in patients predisposed to hypoglycemia (eg, cases of reduced caloric intake, strenuous exercise without repletion of calories, alcohol ingestion or when metformin is combined with another oral antidiabetic agent).
        • Vitamin B12: Decreases absorption of Vitamin B12; monitor for signs and symptoms of vitamin B12 deficiency.
        • Folic acid: Decreases absorption of folic acid; monitor for signs and symptoms of folic acid deficiency.
      • Interaction with Disease

        Administration of oral antidiabetic drugs has been reported to be associated with increased cardiovascular mortality as compared to treatment with diet alone or diet plus insulin. Metformin is substantially excreted by the kidney - the risk of accumulation and lactic acidosis increases with the degree of impairment of renal function. Patients with renal function below the limit of normal for their age should not receive metformin. In elderly patients, renal function should be monitored regularly. Use of concomitant medications that may affect renal function (ie, affect tubular secretion) may affect metformin disposition. Therapy should be suspended for any surgical procedures. Avoid use in patients with impaired liver function. Metformin should be discontinued at the time of or prior to the procedure in patients undergoing radiologic studies in which intravascular iodinated contrast materials are utilized, and withheld for 48 hours subsequent to the procedure, and reinstituted only after renal function has been re-evaluated and found to be normal.

      FAQs about Reclimet Tablet

      • Ques : What is Eclimet tablet?

        Ans : This tablet can be classified as an oral hypoglycemic which is mainly used for the treatment of type 2 diabetes.

      • Ques : What is the use of Reclimet tablet?

        Ans : Reclimet Tablet is used for the treatment and prevention from conditions and symptoms of diseases like the treatment of type 2 diabetes mellitus, maturity-onset diabetes, and non-insulin dependent diabetes mellitus.

      • Ques : What are the side effects of Reclimet tablet?

        Ans : The side effects include visual disturbances, gastrointestinal disturbances, indigestion, hypoglycemia, and angioedema. Apart from these, using this medicine can further lead to change in hematology, jaundice, and transient visual disturbances at the start of treatment. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

      • Ques : What are the instructions for storage and disposal of Reclimet tablet ?

        Ans : Reclimet Tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of Reclimet Tablet.

      • Ques : How long do I need to use reclimet tablet before I see improvement in my condition?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 1 week, before noticing an improvement in the condition.

      • Ques : At what frequency do I need to use reclimet tablet?

        Ans : This medication is generally used once or twice a day. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

      • Ques : Should I use reclimet tablet empty stomach, before food or after food?

        Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken with the food. Please consult the doctor before using it.

      References

      • Gliclazide- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 15 May 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/gliclazide

      • Gliclazide- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 15 May 2019]. Available from:

        https://www.drugbank.ca/drugs/DB01120

      • Metformin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 26 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/metformin

      • Metformin: Important information you need to know- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 26 April 2019]. Available from:

        https://www.drugsbanks.com/metformin/

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Yuvraj Arora MongaMD-Pharmacology, MBBSSexology
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