Reteplase

Reteplase is used in the treatment of heart attacks and improving heart functions. It is a thrombolytic drug, or a type of tissue plasminogen activator that works by breaking up bood clots responsible for the heart problems.

Reteplase should not be used if you are allergic to it or to any ingredient in it, or have blood vessel defects, high blood pressure, internal bleeding, spine or brain surgery, history of stroke, aneurysm. You should consult a doctor before taking Reteplase if you have kidney, heart or liver disease, infection, stomach ulcers, are on blood thinners. It should also be avoided if you are pregnant, plan on becoming pregnant, or are breastfeeding, or if you are on some medicines or supplements.

The reported side effects of Reteplase are sudden headache, vision problems, chest pain, sudden cough, change in heart rate, sudden weakness or numbness in the body, confusion, allergic reactions like rashes, swelling of throat, tongue, face or lips. You should see a doctor immediately if you encounter any of these conditions.

Reteplase is administered as double bolus injection of 10 units each. The time duration of injecting each bolus is over 2 minutes and there should be a 30 minutes interval before giving the second bolus. Only two bolus injections are required for a complete treatment.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Heart Attack

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Nausea

• Vomiting

• Decreased Blood Pressure

• Injection Site Bleeding

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Retefast 18mg injection may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  There is no data available. Please consult doctor before consuming the drug.

• Does this affect kidney function?

  There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

Below is the list of medicines, which contains Reteplase as ingredient

• Retefast 18Mg Injection

  Cipla Ltd

• Vascium 18Mg Injection

  Emcure Pharmaceuticals Ltd

• Retefuse 18Mg Injection

  Lupin Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

Reteplase Through the fibronectin finger-like domain and the Kringle 2 domain Reteplase binds to clots rich with fibrin. After this plasmin is formed as the protease domain then cleaves the Arg/Val bond in plasminogen. The fibrin matrix of the thrombus is thus degenerated, and exerts its thrombolytic action.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.