Roles-D Capsule Sr

This medication is indicated for treating GERD (Gastro-esophageal reflux disease), which not responds to Rabeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Roles-D Capsule Sr is a combination of Domperidone and Rabeprazole. The active ingredients, Domperidone and Rabeprazole fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

It is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

This medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Roles-D Capsule Sr if you have the following conditions:

• An allergy to Roles-D Capsule Sr or any other ingredient of this medicine
• Bleeding problems or blockage in your stomach or in the intestine
• Tumour in the pituitary gland
• Cardiac disease
• Incorrect levels of magnesium, potassium or calcium in the blood
• Severe/moderate liver impairment

• Gastroesophageal Reflux Disease

• Peptic Ulcer

• Allergy

• Tumor Of Pituitary Gland

• Heart Diseases

• Skin Rash

• Diarrhoea

• Headache

• Dizziness

• Weakness

• Insomnia

• Cough

• Stomach Pain

• Rhinitis

• Flatulence

• Dry Mouth

• How long is the duration of effect?

  The effect of this medication lasts up to 6 hours.

• What is the onset of action?

  The peak effect of this medication can be observed within 30 to 60 minutes of administration.

• Are there any pregnancy warnings?

  This medication does not cause any harm to the fetus, but there is no scientific evidence to certify it. Hence, it is best to consult a doctor before consuming it during pregnancy. It is best to be administered orally.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medication should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant. You are suggested to consult your doctor to discuss the potential benefits and risks before taking this medication.

Below is the list of medicines, which have the same composition, strength and form as Roles-D Capsule Sr , and hence can be used as its substitute.

• Cyra-D Capsule SR

  Systopic Laboratories Pvt Ltd

• Pepcia D 30 Mg/20 Mg Capsule Sr

  FDC Ltd

• Rabopep-DSR Capsule

  Seagull Pharmaceutical Pvt Ltd

• Rabitop D 30 Mg/20 Mg Capsule Sr

  Aristo Pharmaceuticals Pvt Ltd

• Rebozen D 30 Mg/20 Mg Capsule Sr

  Leeford Healthcare Ltd

• Rabezox D 30mg/20mg Tablet SR

  Lloyd Healthcare Pvt Ltd

• RABIUM-DSR CAPSULE

  Intas Pharmaceuticals Ltd

• Acera-D Capsule Sr

  Ipca Laboratories Ltd

• Cyclochek Capsule Sr

  Indoco Remedies Ltd

• Strovo D SR Tablet

  Dr. Johns Laboratories Pvt Ltd

• Are there any missed dose instructions?

  Skip the missed dose and resume with the next scheduled dose at the right time. The dose should not get doubled in an attempt to make up for the missed dose.

• Are there any overdose instructions?

  Contact your doctor if an overdose is suspected.

This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Lab Test

  The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.

• Interaction with Medicine

  Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

• Ques : What is Roles-D Capsule Sr?

  Ans : This medication has Domperidone and Rabeprazole as active ingredients present. It performs its action by obstructing the release of acid in the stomach.

• Ques : What are the uses of Roles-D Capsule Sr?

  Ans : This medication is used for the treatment and prevention from conditions and symptoms of diseases like duodenal ulcers, nausea, gastroesophageal reflux diseases, idiopathic gastroparesis, acid-related indigestion, and heartburn symptoms.

• Ques : What are the Side Effects of Roles-D Capsule Sr?

  Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of this medication. These include mouth dryness, weakness, flu, flatulence, stomach disorders, headache, abdominal pain, dizziness, and stomach pain.

• Ques : What are the instructions for storage and disposal Roles-D Capsule Sr?

  Ans : This medication should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 28 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/domperidone

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 28 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184

• Rabeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 28 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/rn/117976-89-3

• Rabeprazole- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 28 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01129