Rzole DSR 30 mg/20 mg Capsule

Rzole DSR Capsule is indicated for treating GERD (Gastro-esophageal reflux disease), which does not respond to Omeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Rzole DSR 30 mg/20 mg Capsule is a combination of Domperidone and Omeprazole. The active ingredients fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

Rzole DSR Capsule also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

Rzole DSR medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Rzole DSR 30 mg/20 mg Capsule if you have the following conditions:

• An allergy to Rzole DSR 30 mg/20 mg Capsule or any other ingredient of this medicine
• Bleeding problems or blockage in your stomach or in the intestine
• Tumour in the pituitary gland
• Cardiac disease
• Incorrect levels of magnesium, potassium or calcium in the blood
• Severe /moderate liver impairment

• Gastroesophageal Reflux Disease

• Peptic Ulcer

• Allergy

  Rzole DSR 30 mg/20 mg Capsule is not recommended for use in people having a known history of allergy to it.

• Tumor Of Pituitary Gland

  Rzole DSR 30 mg/20 mg Capsule is not recommended for use in people having tumor of the pituitary gland.

• Heart Diseases

  Rzole DSR 30 mg/20 mg Capsule is not recommended for use in people having an active heart disease like Congestive Heart Failure.

• Skin Rash

• Diarrhoea

• Headache

• Stomach Pain

• Dizziness

• Weakness

• Dry Mouth

• Cough

• Rhinitis

• Flatulence

• Insomnia

• How long is the duration of effect?

  The effect of this medicine lasts up to 6 hours.

• What is the onset of action?

  The peak effect of Rzole DSR medicine can be observed within 30 to 60 minutes of administration.

• Are there any pregnancy warnings?

  Rzole DSR medicine should be avoided by pregnant women unless suggested by the doctor. The effect of this medicine is not clearly established and hence, doctor consultation is recommended before consumption.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  Rzole DSR medicine is not recommended for use by breastfeeding mothers as there is a risk of side effects on the infant. You are advised to consult your doctors and consider the potential benefit and risks before consuming this medication.

Below is the list of medicines, which have the same composition, strength and form as Rzole DSR 30 mg/20 mg Capsule , and hence can be used as its substitute.

• Omido DSR Capsule

  Shine Pharmaceuticals Ltd

• Domstal Plus 30 mg/20 mg Capsule

  Torrent Pharmaceuticals Ltd

• Odoman 30Mg/20Mg Capsule

  Maan Pharmaceuticals Ltd

• Osif D Capsule

  Sifco Pharma

• Odom 30 Mg/20 Mg Capsule

  Baksun Healthcare Pvt Ltd

• Oskar Dsr 30 Mg/20 Mg Capsule

  Mankind Pharma Ltd

• Viscid OD 30 mg/20 mg Capsule

  Indoco Remedies Ltd

• Rox Dsr 30 Mg/20 Mg Capsule

  Baksun Healthcare Pvt Ltd

• Omross-D SR Capsule

  Emami Frank Ross Ltd

• Are there any missed dose instructions?

  Skip the missed dose and resume with the next scheduled dose at the right time. The dose should not get doubled in an attempt to make up for the missed dose.

• Are there any overdose instructions?

  Contact your doctor if an overdose is suspected. Symptoms of overdose may include drowsiness, agitation, and convulsions and may be more prevalent in infants and children. Immediate medical attention including gastric lavage may be required in severe cases.

Rzole DSR medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Lab Test

  The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.

• Interaction with Medicine

  Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

• Interaction with Disease

  • Kidney Disease: This medication should be used with caution if you are suffering from impaired kidney function. Suitable dose adjustment and safety monitoring is advised, especially if the impairment is severe.
  • Liver Disease: This medicine should be used with caution if you are suffering from impaired liver function. Suitable dose adjustment and safety monitoring are advised, especially if the impairment is mild to moderate. For severe impairment, the use of this medicine is not recommended.
  • Intestinal Disorders: This medication should be used with extreme caution in people having serious intestinal problems like internal bleeding, an obstruction or perforation of the stomach and intestine. Use of alternate medicine is advised in such cases.

• Ques : What is Rzole DSR 30 mg/20 mg Capsule?

  Ans : Rzole DSR Capsule belongs to the class of drugs known as dopamine antagonists along with PPI in combination. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems and also those who take certain medicines for Parkinson’s disease. It contains Domperidone and Omeprazole as active ingredients. Rzole D Capsule works by blocking the dopamine receptors; blocking the production of acid in the stomach.

• Ques : What is the use of Rzole DSR 30 mg/20 mg Capsule?

  Ans : Rzole DSR Capsule is used for the treatment and prevention from conditions and symptoms of diseases like acidic stomach, food pipe healing, gas, abdominal distress, treatment for symptoms associated with idiopathic or diabetic gastroparesis. Besides these, it can also be used to treat conditions like gastroesophageal reflux disease, treatment for intractable nausea and vomiting, heartburn, bitter fluid into the stomach. The patient should inform the doctor about any ongoing medications and treatment before using Rzole DSR Capsule to avoid undesirable effects.

• Ques : What are the side effects of Rzole DSR 30 mg/20 mg Capsule?

  Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of Rzole DSR Capsule. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include somnolence, akathisia, diarrhea, rash, and pruritus. Apart from these, using this medicine may further lead to breast enlargement or tenderness, galactorrhoea, and amenorrhea. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

• Ques : What are the instructions for storage and disposal of Rzole DSR 30 mg/20 mg Capsule?

  Ans : Rzole DSR Capsule should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of Rzole DSR Capsule. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

• Ques : How long do I need to use Rzole DSR 30 mg/20 mg Capsule before I see improvement in my condition?

  Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition. So please consult your doctor.

• Ques : At what frequency do I need to use Rzole DSR 30 mg/20 mg Capsule?

  Ans : Rzole DSR medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

• Ques : Should I use Rzole DSR 30 mg/20 mg Capsule empty stomach, before food or after food?

  Ans : Rzole DSR Cap is advised to be consumed orally. The salts involved in this medication, work properly on an empty stomach. It is advised to consume this medication, 1 hour before having food and at least 2 hours after having food. Taking it with food may upset your stomach. Please consult the doctor before use.

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 27 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/domperidone

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 27 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184

• Omeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 27 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/omeprazole

• Omeprazole- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 27 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00338