Sacubitril

Sacubitril is an anti-hypertensive drug used in combination with Valsartan as a treatment and prevention drug for chronic heart failure and other heart conditions. It works by inhibiting a prodrug neprilysin which reduces the strain on the failing heart.

Consult your doctor if you experience any side-effects due to this medicine. Some common side effects that it can cause include low blood pressure, swelling in ankles and feet, feeling short of breath, fainting, dizziness, high blood potassium levels, muscle weakness, painful urination, little or no urination, tingly feeling, slow heart rate, weak pulse, cough and renal impairment.

You should not use this medicine if you are allergic to it or if you have ever had a severe allergic reaction to any blood pressure medication. If you have diabetes or a kidney disease, do not take this medication together with any medication that contains aliskiren. Inform your doctor if you have liver disease, diabetes or if you are on a low-salt-diet, dehydrated, pregnant or breastfeeding.

The usual initial dose for heart problems in adults is 49 mg of Sacubitril taken with 51 mg Valsartan, by mouth, twice a day. Adjustment of dose will be done by the doctor depending on your response to treatment.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Hypertension

• Heart Failure

• Heart Attack

• Diabetic Kidney Disease

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Fatigue

• Weakness

• Orthostatic Hypotension

• Dizziness

• Anemia

• Vertigo

• Renal Impairment

• Increased Potassium Level In Blood

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Cidmus 100mg tablet is unsafe to use during pregnancy.
  There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

• Are there any breast-feeding warnings?

  Cidmus 100mg tablet is probably safe to use during breastfeeding. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Occasionally dizziness or weariness may occur.

• Does this affect kidney function?

  There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Below is the list of medicines, which contains Sacubitril as ingredient

• Azmarda 200Mg Tablet

  Cipla Ltd

• Azmarda 50Mg Tablet

  Cipla Ltd

• Cidmus 50Mg Tablet

  Lupin Ltd

• Cidmus 100Mg Tablet

  Lupin Ltd

• Vymada 100 Mg Tablet

  Novartis India Ltd

• Azmarda 100Mg Tablet

  Cipla Ltd

• Vymada 200Mg Tablet

  Novartis India Ltd

• Vymada 50 Mg Tablet

  Novartis India Ltd

• Cidmus 200Mg Tablet

  Lupin Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

This medication works by blocking the enzyme neprilysin, which leads to the degeneration of atrial and brain natriuretic peptide. When these peptides remain excessively active the blood pressure is reduced, as the blood volume is lowered.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Sacubitril-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 10 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/sacubitril

• Sacubitril-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 10 June 2022].Available from:

  https://go.drugbank.com/drugs/DB09292

• Sacubitril tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 10 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=000dc81d-ab91-450c-8eae-8eb74e72296f