Silofast D 8 Combipack

This is a combination medication which has Silodosin and Dutasteride as active ingredients. It falls under a category of drugs known as alpha-blockers. This medication is used to treat enlarged prostate (benign prostatic hyperplasia or BPH). It functions by relaxing the prostate and bladder muscles allowing greater urine flow.

This medication is primarily used by men. It reduces the signs and symptoms of BPH. The dosage for this medication should be determined by the doctor.

• Benign Prostatic Hyperplasia

• Renal Impairment

• Dizziness

• Ejaculation Disorder

• Is It safe with alcohol?

  Taking this medication with alcohol may have additive effects in lowering your blood pressure. You may experience a headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.

• Are there any pregnancy warnings?

  This medication is probably safe to use during pregnancy. Animal studies have shown low or no adverse effect on the fetus, however, there are limited human studies. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  It may cause dizziness. Exercise caution if you have to drive or operate a machinery.

• Does this affect kidney function?

  No dose adjustment is needed for patients with the mild renal disease, and dose adjustment is required in moderate renal disease.Not advisable in patients with the severe renal disease.

• Does this affect liver function?

  No dose adjustment is needed for patients with the mild to moderate liver disease.Not advisable in patients with the severe liver disease.

Below is the list of medicines, which have the same composition, strength and form as Silofast D 8 Combipack , and hence can be used as its substitute.

• Alphacept-D 8 Combipack

  Lupin Ltd

• Sildura 8 Combipack

  Sun Pharmaceutical Industries Ltd

• Silodal-D 8 Combipack

  Sun Pharmaceutical Industries Ltd

• Silotime D 8Mg/0.5Mg Tablet

  Intas Pharmaceuticals Ltd

• Maxvoid Plus 8mg/0.5mg Tablet

  Alkem Laboratories Ltd

• Rapilif-D 8/0.5 Combipack

  Ipca Laboratories Ltd

• Flospurt-D Tablet

  Zydus Cadila

• New Geripod-D Capsule

  Alembic Pharmaceuticals Ltd

• Silocap D 8 Mg/0.5 Mg Tablet

  Overseas Healthcare Pvt Ltd

• Are there any missed dose instructions?

  If you miss a dose of this medication, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

• Are there any overdose instructions?

  In case of overdose, consult your doctor.

This medication works as an antagonist of the alpha-1 adrenoreceptor selective for the prostrate. It binds to and blocks these receptors which lower intraurethral pressure, relaxes smooth muscles and improves urine flow. Dutasteride is primarily used as a form of treatment for enlarged prostate in males and also has secondary functionalities. The drug restricts the conversion of testosterone into dihydrotestosterone. DHT is responsible for the swelling of the prostate.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  This medication interacts with Amitriptyline, Alprazolam, Nefazodone, Clotrimazole, Baclofen, Chlordiazepoxide, Canagliflozin, and Conivaptan.

• Interaction with Disease

  This medication interacts with Renal Dysfunction and Hepatic impairment.