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Overview

Sitagliptin

Prescription vs OTC : Prescription by Doctor required

About Sitagliptin

Sitagliptin is a drug prescribed to patients with type 2 diabetes. It helps in reducing the blood sugar level in the body. This is classified under the DDP-4 inhibitor class of medications. It should be taken with diet and regular exercise. Sometimes prescribed along with other medications.

This drug comes as a tablet and is consumed orally. However, note that it is used to lower blood sugar levels only and not to cure diabetes in itself. It is not used for treating type 1 diabetes and is not advised for people with high blood ketone levels.

You should consult your doctor before you use this drug if you are pregnant, breastfeeding, have any kidney problems. It is also not advised for people that have a history of conditions like gallstones, Angioedema or swelling of the pancreas.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the uses of Sitagliptin

    • Type 2 Diabetes

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the contraindications of Sitagliptin ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the side effects of Sitagliptin ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    Key highlights of Sitagliptin

    • Is It safe with alcohol?

      Taking this drug with alcohol may affect blood glucose levels in patients with diabetes. Consuming this drug with alcohol can cause several adverse effects.

    • Are there any pregnancy warnings?

      This drug should not be consumed during pregnancy unless necessary. Consulting a doctor is mandatory to discuss the benefits and risks before taking the medicine.

    • Are there any breast-feeding warnings?

      This drug can be given to the women who are breastfeeding but only after evaluating the benefits and risks with the doctor.

    • Is it safe to drive while on this medicine?

      It may cause hypoglycemia Exercise caution if you have to drive or operate a machinery.

    • Does this affect kidney function?

      No dose adjustment is needed for patients with mild renal disease. Not advisable in patients with moderate to severe renal disease. Please consult your doctor.

    • Does this affect liver function?

      No dose adjustment is needed for patients with the mild and moderate liver disease. Please consult your doctor.

    • What is the onset of action?

      No information available.

    • How long is the duration of effect?

      No information available.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    • Are there any missed dose instructions?

      If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    Medicines containing Sitagliptin

    Below is the list of medicines, which contains Sitagliptin as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

    How does this medication work?

    This medication falls under the category of a hypoglycemic drug that works by competitively binding to and inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This inhibition increases the number of active incretins (GLP-1 and GIP).

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Diabetologist before using this medicine.

      What are the interactions of Sitagliptin ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        No information available.
      • Interaction with Medicine

        This medication interacts with ketoconazole, itraconazole, ritonavir, and clarithromycin.
      • Interaction with Food

        No information available.
      • Interaction with Disease

        No information available.

      FAQs about Sitagliptin

      • Ques : What is Sitagliptin?

        Ans : This drug is a drug prescribed to patients with type 2 diabetes. It helps in reducing the blood sugar level in the body.

      • Ques : How long do I need to use Sitagliptin before I see improvement in my condition?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition.

      • Ques : At what frequency do I need to use Sitagliptin?

        Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

      • Ques : Should I use Sitagliptin empty stomach, before food or after food?

        Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

      • Ques : What are the instructions for the storage and disposal of Sitagliptin?

        Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children.

      References

      • Sitagliptin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 21 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/sitagliptin

      • Sitagliptin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 21 June 2022].Available from:

        https://go.drugbank.com/drugs/DB01261

      • SITAGLIPTIN tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 21 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=SITAGLIPTIN

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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