Sompraz 40 MG Tablet

Sompraz 40 MG Tablet is used in the treatment of conditions caused by excessive production of acid in the stomach. The conditions may include erosive esophagitis, gastroesophageal reflux disease (GERD), Helicobacter pylori infection and Zollinger-Ellison syndrome (tumors in the pancreas or in the upper part of the small intestine).

Sompraz 40 MG Tablet is used for short-term (4-8 weeks) treatment of severe erosive esophagitis (grade 2 or above), diagnosed by endoscopy and short-term treatment of symptomatic gastroesophageal reflux disease (GERD) poorly responsive to customary medical treatment.

It is also used for the treatment of heartburn and other symptoms associated with GERD; pathological hypersecretory conditions; peptic ulcer disease; gastric ulcer therapy; maintenance of healing of erosive esophagitis; approved for combination use in the eradication of H. pylori in patients with active duodenal ulcer.

Apart from that, it can also help in preventing stomach ulcer that is caused due to the consumption of nonsteroidal anti-inflammatory drugs (NSAID). The medication is available as a delayed-release capsule or in the form of a liquid suspension.

Belonging to the drug group of proton pump inhibitors, this medication blocks the proton pump in your stomach’s cells. When this proton pump gets blocked, there will be less production of acid in your stomach.

The dosage of this medication is decided by your doctor based on your age, the severity of the condition, your medical history and the reaction of your body after taking the first dose.

It should be kept in mind that this medicine is processed by the liver. If you have chronic liver disease, the body will be unable to process it well, causing a build-up of the drug. Also, this medicine can pass on to a child through his/her mother by breastfeeding. Hence, both pregnant and breastfeeding mothers must consult a doctor before taking the medication.

This medicine is approved for combination use in the eradication of H. pylori in patients with active duodenal ulcer. The most common side effects associated with Omeprazole include diarrhea, gas, vomiting, headache, nausea and stomach aches.

Although rare, certain severe adverse reactions are increased possibility of bone fractures, decreased magnesium levels inside the body, seizures, irregular heart-beats, jitteriness, muscle spasms and weakness, feet/hand spasms, voice box spasms, etc.

The likelihood of these severe side effects goes up if you take this medicine for over a period of 3 months. Also, prolonged intake of this medication (usually over a period of three years) can result in your body’s decreased ability to absorb Vitamin B12.

Other possible (albeit rare) side effects include diarrhea, inflammation of the intestine and the stomach lining, damage to the kidneys, allergic reactions, weight loss, and fever.

Symptoms of overdose include hypothermia, sedation, convulsions, decreased respiratory rate demonstrated in animals only. Treatment is supportive; not dialyzable.

• Erosive Esophagitis

• Gastroesophageal Reflux Disease

• Helicobacter Pylori Infection

• Zollinger-Ellison Syndrome

• Other Forms Of Ulcers

• Acidity

• Heartburn

• Allergy

• Abdominal Pain

• Fever

• Joint Pain

• Sore Throat

• Loss Of Appetite

• Constipation

• Diarrhoea

• Difficulty In Breathing

• Dizziness

• Muscle Pain

• Drowsiness

• Rash

• Back Pain

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 16-18 hours.

• What is the onset of action?

  The effect of this medicine can be observed within an hour of administration.

• Are there any pregnancy warnings?

  This medicine can be used by pregnant women only when necessary and the potential benefits outweigh the risks involved. Consult your doctor before taking this medicine.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for use by breastfeeding women as it may cause some harm to the infant. Consult your doctor before taking this medicine.

• Is It safe with alcohol?

  Caution must be taken. Avoid consuming alcohol along with this medicine.

• Is it safe to drive while on this medicine?

  It is unknown whether this medicine alter the ability of patients driving skills. It patient experience any side effects, he must avoid driving.

• Does this affect kidney function?

  It is safe to use Sompraz 40 MG Tablet in patients with kidney disease.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Adjustment of dose is needed, kindly consult your doctor before taking this medication.

Below is the list of medicines, which have the same composition, strength and form as Sompraz 40 MG Tablet , and hence can be used as its substitute.

• Omipure Fast 40 MG Tablet

  Mankind Pharmaceuticals Ltd

• Esoz Fast 40 MG Tablet

  Glenmark Pharmaceuticals Ltd

• Pirazole S 40 MG Tablet

  Abbott Healthcare Pvt. Ltd

• Raciper 40 MG Tablet

  Ranbaxy Laboratories Ltd

• Oskar-S 40 MG Tablet

  Mankind Pharmaceuticals Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose should be skipped.

• Are there any overdose instructions?

  Contact your doctor immediately if an overdose is suspected.

It is a proton pump inhibitor drug and binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Lab Test

  Neuroendocrine tumor diagnosis

  This medication should not be used while undergoing the neuroendocrine/carcinoid tumor test as it might give a false-positive result for this diagnostic test.

• Interaction with Medicine

  • Clopidogrel: Report the use of either of the medicine to the doctor. Your doctor may prescribe a safer alternative for reducing the stomach acidity while you are being treated with Clopidogrel.
  • Ketoconazole: This medication should be used with Ketoconazole or other antifungals of the same group with caution. Inform the doctor about the usage of either of these medications so that safer alternatives can be prescribed.
  • Methotrexate: This medication should not be used with Methotrexate. The use of either of the drugs should be reported to the doctor so that a safer substitute could be prescribed.
  • Warfarin: Usage of this medication with Warfarin should be strictly monitored by the doctor. Suitable adjustment in dosage and monitoring of Prothrombin time is necessary to ensure safety. Any symptoms like unusual bleeding, swelling, vomiting, or presence of blood in urine should be reported immediately.
  • Nelfinavir: This medication is not recommended for use when the patient is already taking anti-viral medications like Nelfinavir or other drugs used in the management of HIV Infection.
  • Digoxin: This medication should be used with caution if the patient is on Digoxin. Prior usage of any of these drugs should be informed to the doctor. Any symptoms like nausea, vomiting, diarrhea, loss of appetite, disturbances in vision, and abnormalities in heartbeat should be reported immediately.

• Interaction with Disease

  • Liver Disease: Any history of liver disease has to be reported to the doctor. Suitable dose adjustment is required based on the extent of the liver impairment.
  • Osteoporosis: Suitable dose adjustment have to be made in patients who suffer from Osteoporosis related fracture.
  • Hypomagnesemia: Inform your doctor about magnesium level imbalance in the body. Regular monitoring is advised for patients taking Esomeprazole in such cases.

• Ques : What is Sompraz 40 mg tablet?

  Ans : Sompraz tablet works as a proton pump inhibitor and is used in the treatment of stomach ulcers, gastroesophageal reflux disease(GERD) and other acidity related disorders. It can also be used to prevent stomach ulcer which is caused due to the consumption of nonsteroidal anti-inflammatory drugs (NSAID). This tablet contains Esomeprazole as an active ingredient. Sompraz 40 Tablet works by decreasing the amount of acid produced in the stomach.

• Ques : What is the use of Sompraz 40 mg tablet?

  Ans : This tablet is used for the treatment and prevention from conditions and symptoms of diseases like erosive esophagitis, gastroesophageal reflux disease, helicobacter pylori infection, zollinger-ellison syndrome.

• Ques : What are the side effects of Sompraz 40 mg tablet?

  Ans : The side effects include headache, nausea, flatulence, stomach pain and skin rash. Besides these, using this medicine may further lead to irregular heartbeat, diarrhea, unusual tiredness and weakness, fever, and decreased appetite. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

• Ques : What are the instructions for storage and disposal of Sompraz 40 mg tablet ?

  Ans : This tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : How long do I need to use sompraz 40 mg tablet before I see improvement in my condition?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 to 3 days. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to use this medication.

• Ques : At what frequency do I need to use sompraz 40 mg tablet?

  Ans : This medication is generally used once or twice a day. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

• Ques : Should I use sompraz 40 mg tablet empty stomach, before food or after food?

  Ans : This medication is advised to be consumed orally. The salts involved in this medication, work properly on an empty stomach. It is advised to consume this medication, 1 hour before having food and at least 2 hours after having food. Taking it with food may upset your stomach. Please consult the doctor before use.

• Ques : What is the half-life of Sompraz 40 MG Tablet?

  Ans : The half-life of Sompraz 40 MG Tablet is between 1 to 1.5 hours.

• Ques : Does Sompraz 40 MG Tablet induce diarrhea?

  Ans : Sompraz 40 MG Tablet may cause diarrhea in some patients, however, it should improve in some time.

• Ques : Does Sompraz 40 MG Tablet makes the body susceptible to infections?

  Ans : The excessive usage of Sompraz 40 MG Tablet makes the body susceptible to bacterial infection, thus, it should be used with caution.

• Ques : What are the dietary specifications while taking Sompraz 40 MG Tablet?

  Ans : There are no specific dietary guidelines unless the doctor instructs otherwise.

• Ques : What is the route of administration of Sompraz 40 MG Tablet?

  Ans : Sompraz 40 MG Tablet is administered orally with a glass of water.

• Esomeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/esomeprazole

• Esomeprazole- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 10 May 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00736

• Esomeprazole, Uses, Side Effects And Doses- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 15 May 2019]. Available from:

  https://www.drugsbanks.com/esomeprazole/