Trama Plus 325 mg/37.5 mg Tablet

Trama Plus 325 mg/37.5 mg Tablet is used a pain-relieving medication. It is primarily used to treat acute pain. The conditions of acute pain include backache, headache, arthritis and toothache, etc.

This medication is a combination of paracetamol and tramadol. These drugs fall under the class of analgesics, belonging to the category of NSAID and opioid agonist, respectively. This medication also reduces pain in the body caused due to fever.

You should not consume this tablet if:

• You are allergic to this medicine.
• You are suffering from a serious liver disorder.
• You normally consume more than 3 alcohol beverages per day or have a history of alcoholism.

You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.

The medicine must be swallowed whole, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.

• Acute Pain

• Allergy

• Analgesic Nephropathy (Kidney Disease)

• Liver Disease

• Nausea Or Vomiting

• Allergic Skin Reaction

• Gastric / Mouth Ulcer

• Anemia

• Fatigue

• Stevens-Johnson Syndrome (Sjs)

• Chills

• Confusion

• Headache

• Acid Or Sour Stomach

• Decreased Appetite

• How long is the duration of effect?

  The effect lasts for an average of 4-6 hours.

• What is the onset of action?

  The effect of this drug can be observed within an hour of administration.

• Are there any pregnancy warnings?

  It should be used only when necessary after consulting a doctor in pregnant women.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine.

Below is the list of medicines, which have the same composition, strength and form as Trama Plus 325 mg/37.5 mg Tablet , and hence can be used as its substitute.

• Nicodol Plus 325 Mg/37.5 Mg Tablet

  Abbott India Ltd

• Tramacad P 325 Mg/37.5 Mg Tablet

  Cadila Pharmaceuticals Ltd

• Trson P 325Mg/37.5Mg Tablet

  Unison Pharmaceuticals Pvt Ltd

• Synerdol Forte 325 Mg/37.5 Mg Tablet

  Seagull Labs (I) Pvt Ltd

• Tram Proxyvon 325 Mg/37.5 Mg Capsule

  Wockhardt Ltd

• Rosetra P 325 Mg/37.5 Mg Tablet

  Almet Corporation Ltd

• Kamadol P 325Mg/37.5Mg Tablet

  Karnataka Antibiotics & Pharmaceuticals Ltd

• Dol A 325 Mg/37.5 Mg Tablet

  Serve Pharmaceuticals

• Pentazen 325 mg/37.5 mg Tablet

  Ind Swift Laboratories Ltd

• Parexia T 325 mg/37.5 mg Tablet

  Heal India Laboratories

• Are there any missed dose instructions?

  The missed dose should be taken as soon as possible.

• Are there any overdose instructions?

  An overdosage could cause harmful effects on the body.

This medication is a combination of Paracetamol and Tramadol. Both the drugs fall under the class of analgesic. Thus medications produce its action following two different paths of the mechanism of action.

Firstly, it selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It activates certain receptors in the brain that inhibit pain signals.

Secondly, it acts on certain specific pain receptors in the brain and inhibits the reuptake of norepinephrine, serotonin. It also enhances the release of serotonin thereby changing the perception and response to pain.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  N/A

  You should avoid consuming alcohol while taking this medicine. Symptoms like fever, chills, rashes, joint pain and swelling, excessive weakness, nausea should be immediately reported to the doctor.

• Interaction with Lab Test

  5-HIAA Urine Test

  You may get a false-positive result for this test if you take Trama Plus 325 mg/37.5 mg Tablet.

• Interaction with Medicine

  null

  One must take caution while taking this medicine. This medication may interact with other medication like Ketoconazole, Metformin, Anti-hypertensives if administered concomitantly.

• Interaction with Food

  Food

  Information not available.

• Interaction with Disease

  Disease

  Patients suffering from liver disease should use some other safer alternative.

• Ques : What is Trama Plus 325 mg/37.5 mg Tablet?

  Ans : This medication performs its action by obstructing the release of pain and fever chemical messengers.

• Ques : What are the uses of Trama Plus 325 mg/37.5 mg Tablet?

  Ans : It is used for the treatment and prevention from conditions and symptoms of diseases like Post immunization pyrexia, menstrual cramps and fever.

• Ques : What are the Side Effects of Trama Plus 325 mg/37.5 mg Tablet?

  Ans : Allergic reaction, gastric ulcers, fatigue, anemia, nausea and vomiting are possible side effects.

• Ques : What are the instructions for storage and disposal Trama Plus 325 mg/37.5 mg Tablet?

  Ans : This medicine should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : Should I use Trama Plus 325 mg/37.5 mg Tablet empty stomach, before food or after food?

  Ans : If you take this medication with the food, the reactions that took place in the body carry-outs in a much effective manner.

• Ques : How long do I need to use Trama Plus 325 mg/37.5 mg Tablet before I see improvement of my conditions?

  Ans : This medication should be consumed, until the complete eradication of the disease. It is advised to use, till the time directed by your doctor.

• Ques : Is there any food or drink I need to avoid?

  Ans : You can follow your normal diet under the usage of this medication.

• Ques : Will Trama Plus 325 mg/37.5 mg Tablet be more effective if taken in more than the recommended dose?

  Ans : There is no need to take this medication more than its recommended doses.

• Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 10 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/paracetamol

• Acetaminophen- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 10 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00316

• Tramadol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 10 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/tramadol

• Tramadol- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 10 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00193