Trenaxa 500 MG Tablet

Trenaxa 500 MG Tablet is prescribed to stop heavy bleeding. It works as an antifibrinolytic and thus stops the blood clots from disintegrating very fast, which in turn reduces bleeding.

It is prescribed for short-term use (2 - 8 days) in hemophilia patients, during and following tooth extraction. This helps in the reduction or prevention of haemorrhage. It is also used as an alternative to aminocaproic acid for subarachnoid hemorrhage (SAH).

Patients are generally discouraged from taking Trenaxa 500 MG Tablet if-

• They are allergic to any component present in the drug
• They have a problem of blood clots that are present in the brain, eye, or lungs.
• They have bleeding because of a kidney problem or brain problem.
• They experience irregular bleeding but its reason has not yet been determined
• They are currently on birth control, like the pill or even the vaginal ring. This is primarily because such birth controls contains estrogen as well as progestin.

Before you start Trenaxa 500 MG Tablet provide your doctor a detailed medical history of your current health condition. Do not forget to inform him about any allergies you have or conditions like kidney problems and issues with vision. Also inform him if you are with pregnant or planning to conceive in the near future.

Trenaxa 500 MG Tablet should be taken as per the directions given by your doctor. The drug is meant for oral consumption and can be taken before or with a meal. It is best that you swallow the drug whole with the help of water or any other liquid. Avoid crushing or chewing the tablet as your body will not be able to absorb it properly. The drug should only be taken after the start of a menstrual period.

Taking medicines result in some side effects, but most people may not experience any or if they do, the side effects are very minor. Trenaxa 500 MG Tablet can lead to some side effects like- headache, pain in the joints, spasms, onset of sinus congestion, tiredness and pain in the stomach.

Some severe side effects that can result when you take Trenaxa 500 MG Tablet includes allergic reaction, seizures, dizziness and changes in vision. If you experience a major side effect get in touch with your health care provider as soon as possible.

• Short-Term Management Of Hemorrhage

• Subarachnoid Hemorrhage

• Allergy

• Acquired Defective Color Vision

• Obstructive Blood Clotting Disorder

• Subarachnoid Hemorrhage

• Nausea

• Diarrhoea

• Vomiting

• Hypotension

• Deep Vein Thrombosis

• Blurred Vision

• Menstrual Abnormalities

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 2-10 hours.

• What is the onset of action?

  The effect of this medicine can be observed within 30 minutes of oral administration.

• Are there any pregnancy warnings?

  Use of this medicine by pregnant women is not recommended unless absolutely necessary. Consult your doctor before taking this medicine.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine can be used by women who are breastfeeding as the risk of adverse effects of nursing infants are less. Consult your doctor before taking this medicine.

• Does this affect kidney function?

  Dose adjustment needed in case of renal dysfunction. Consult your before taking Trenaxa 500 MG Tablet.

• Does this affect liver function?

  No relevant data available. Consult your doctor before taking Trenaxa 500 MG Tablet.

• Is It safe with alcohol?

  Consumption of alcohol along with this medication may cause excessive dizziness or drowsiness.

• Is it safe to drive while on this medicine?

  This medicine usually does not affect the patients ability to drive.

Below is the list of medicines, which have the same composition, strength and form as Trenaxa 500 MG Tablet , and hence can be used as its substitute.

• Clip 500 MG Tablet

  Fdc Ltd

• Pausera 500 MG Tablet

  Pfizer Ltd

• Tranfib 500 MG Tablet

  Cipla Ltd

• Tranlok 500 MG Tablet

  Aristo Pharmaceuticals Pvt.Ltd

• Tranomac 500 MG Tablet

  Macleods Pharmaceuticals Pvt.Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember given that the next scheduled dose is at least 6 hours away. If you missed a scheduled injection of this medicine, then contact your doctor for further instructions.

• Are there any overdose instructions?

  Contact a doctor immediately if an overdose is suspected.

Trenaxa 500 MG Tablet acts on an enzyme plasmin which is primarily responsible for the dissolution of clots. It binds to the plasmin receptors and preserves the clot formed.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  • Tamoxifen: Report the use of either of the medicine to the doctor. Since the risk of adverse effects is high, your doctor may determine the best possible course of treatment. It is recommended to take appropriate precautionary measures while taking them together.
  • Ethinyl Estradiol: Report the use of any hormonal contraceptive, irrespective of the form in which it is consumed, to the doctor. Use of these medicines together are not recommended as the risk of adverse effects are significantly high. Report any incidence of chest pain, breathing difficulties, the presence of blood in cough or urine to the doctor on priority.
  • Tretinoin: Report the use of either of the medicine to the doctor. Using these medicines together may increase the risks of serious adverse effects especially in the initial stages of treatment. Seek immediate help if you experience symptoms of internal blood clots like shortness of breast, chest pain, presence of blood in urine or cough, swelling of arms and legs.
  • Factor IX complex: Report the use of any medicine used for improving the clot formation process to the doctor. Your doctor may prescribe an alternate medication or schedule the dosing in such a way that there is sufficient time gap between the consumption of these medicines.

• Interaction with Disease

  This medication interacts with Kidney disease.

• Ques : What is Trenaxa 500 mg tablet?

  Ans : Trenaxa is a medication which has Tranexamic Acid as an active factor present in it. This medicine performs its action by preventing bleeding. This tablet is used to treat conditions such as Heavy menstrual bleeding, Severe loss of blood, Blood clotting problems, and Swelling in various body parts.

• Ques : What is the use of Trenaxa 500 mg tablet?

  Ans : Trenaxa tablet is a medication, which is used for the treatment and prevention from conditions such as Heavy menstrual bleeding and Severe loss of blood.

• Ques : What are the side effects of Trenaxa 500 mg tablet?

  Ans : Side effects of this tablet are Fainting, Unusual pain or swelling in arms or legs, Nausea, Sudden breathlessness, Coughing up of blood, Loose motion, Vomiting, Allergic skin reaction, Pain or feeling of heaviness in chest, Diarrhea, Blurred vision, Low blood pressure, and Blood vessel obstruction by blood clots.

• Ques : Is Trenaxa an over the counter product?

  Ans : No, Trenaxa is not an over the counter product. it is available as a prescription medicine only.

• Ques : How long do I need to use trenaxa 500 mg tablet before I see improvement in my condition?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 6 hours to 1 day. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to use this medication.

• Ques : At what frequency do I need to use trenaxa 500 mg tablet?

  Ans : This medication is generally used once or twice a day but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

• Ques : Should I use trenaxa 500 mg tablet empty stomach, before food or after food?

  Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken with the food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

• Ques : What are the instructions for the storage and disposal of trenaxa 500 mg tablet?

  Ans : This medication contains salts which are suitable to store only at room temperature. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

• Ques : Can Trenaxa 500 MG Tablet cause pulmonary embolism?

  Ans : The medication promotes blood clotting. It is not known to facilitate a blood clot to travel to the lungs (pulmonary embolism). Pulmonary embolism is not a common side effect in patients taking Trenaxa. However, it may occur in overdosing patients with long bedrest or prone individuals.

• Ques : Can I take Trenaxa 500 MG Tablet for more than 5 days?

  Ans : The dose and duration of Trenaxa 500 MG Tablet depends on the type of disease for which it is prescribed. For heavy bleeding during monthly menstruation, it is usually prescribed for up to 5 days.

• Ques : Does Trenaxa 500 MG Tablet affect fertility?

  Ans : No, the medication is not known to have any effect on fertility. It is usually prescribed for heavy menstrual bleeding. Currently, there exists no evidence that suggests interference of this medicine with ovulation (release of eggs from the ovaries).

• Ques : Can Trenaxa 500 MG Tablet be taken for nose bleeding?

  Ans : Yes, the medication can be consumed for nose bleeding as well.

• Tranexamic Acid- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/tranexamic%20acid

• TRANEXAMIC ACID- tranexamic acid tablet - Daily Med [Internet]. dailymed.nlm.nih.gov. 2016 [Cited 16 May 2019]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=031bf7c2-3b07-469d-bc5a-31fc6238e25f

• Tranexamic Acid- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 10 May 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00302