Trihexyphenidyl
About Trihexyphenidyl
Trihexyphenidyl is known to be an anticholinergic, thus it effectively relaxes some muscles of the body by stalling nerve impulses. The drug is used in the treatment of Parkinson’s disease and other conditions with similar symptoms and also for the treatment of drug-induced extrapyramidal effects.
Doctor’s generally do not recommend this medicine to patients who may be allergic to components present in it or patients who have problems like angle closure glaucoma, bowel and stomach issues, heart issues, an esophagus that has narrowed or blockage of the urinary tract.
Certain medical conditions can reduce the effectiveness of the drug or create complications with the treatment. Thus before you start taking Trihexyphenidyl provide your doctor a detailed medical history, and ensure that it includes the health issues you currently have and related medicines you are taking.
Pregnant women or women who are planning to have a baby should also inform their doctor before taking this drug. The same applies for breast feeding women. It is best that you tell your medical practitioner about any kidney or liver problems you suffer from as well.
Trihexyphenidyl should be taken orally, either before a meal or after. If you mouth becomes extremely dry after you take the tablet, it is recommended that you take your dose before food. Although patients who suffer from nausea are generally advised to take the drug after food.
Like all medicines, even Trihexyphenidyl results in some side effects. You may suffer from some minor side effects like constipation, blurry vision, dryness of the mouth, feeling sleepy, increased sensitivity to light and headache.
Although major side effects are very rare, immediate medical aid should be sought if they do occur. For instance get in touch with your doctor if you experience chest pain, problems with swallowing food, problems while urinating or develop fever accompanied with chills.
Take exactly as directed; with meals if GI upset occurs, before meals if dry mouth occurs, after eating if drooling or if nausea occurs. Take at the same time each day. Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake); void before taking medication.
Do not use alcohol and all prescription or OTC sedatives or CNS depressants without consulting prescriber. You may experience drowsiness, confusion, or vision changes (use caution when driving, climbing stairs, or engaging in tasks requiring alertness until response to drug is known).
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.
What are the uses of Trihexyphenidyl
Drug-Induced Extrapyramidal Symptoms
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.
What are the contraindications of Trihexyphenidyl ?
Narrow Angle Glaucoma
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.
What are the side effects of Trihexyphenidyl ?
Tachycardia
Confusion
Agitation
Headache
Nervousness
Dry Skin
Increased Sensitivity To Light
Weakness
Blurred Vision
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.
Key highlights of Trihexyphenidyl
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 6 to 12 hours.
What is the onset of action?
The effect of this medicine can be observed in 1 hour.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Is it habit forming?
No habit forming tendency has been reported
Are there any breast-feeding warnings?
This medicine is not recommended in breastfeeding women.
Is It safe with alcohol?
Consumption of alcohol must be avoided while taking this medicine.
Is it safe to drive while on this medicine?
Driving must be avoided while taking this medicine as this drug might affect the patients consciousness.
Does this affect kidney function?
Limited information is available regarding its use in patients with kidney disease. Kindly consult your doctor before taking it.
Does this affect liver function?
Limited information is available regarding its use in patients with liver disease. Kindly consult your doctor before taking it.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.
What are the dosage instructions?
Missed Dose instructions
If you miss a dose of Trihexyphenidyl, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Are there any overdose instructions?
Seek emergency medical treatment or contact the doctor in case of an overdose.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.
Where is the Trihexyphenidyl approved?
India
United States
Japan
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.
Medicines containing Trihexyphenidyl
Below is the list of medicines, which contains Trihexyphenidyl as ingredient
- Shicalm Plus 5 Mg/2 Mg Tablet
Shine Pharmaceuticals Ltd
- Trikotame 5 MG Tablet
Triko Pharmaceuticals
- Schizonil H 2.5 Mg/1 Mg Tablet
D D Pharmaceuticals
- Bexol 2 MG Tablet
Intas Pharmaceuticals Ltd
- Relihexy 2 MG Tablet
Reliance Formulation Pvt Ltd
- Resque-Plus Tablet
Talent India
- Risp Forte 4 Mg/2 Mg Tablet
D D Pharmaceuticals
- Kivicalm Forte Tablet
Kivi Labs Ltd
- Lahexy 2 MG Tablet
La Pharmaceuticals
- Rospitril Plus 3 Mg/2 Mg Tablet
Arinna Lifescience Pvt Ltd
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.
How does this medication work?
This medication works by blocking cholinergic activity in the central nervous system and reduces the body secretions, increases the heart rate, dilates the pupils and reduces spasm of smooth muscle. It also increases dopamine which is used for smooth muscle movement.
Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.
What are the interactions of Trihexyphenidyl ?
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
- test
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
- Decreased effect: May increase gastric degradation of levodopa and decrease the amount of levodopa absorbed by delaying gastric emptying; the opposite may be true for digoxin.
- Therapeutic effects of cholinergic agents (tacrine, donepezil) and neuroleptics may be antagonized.
- Increased toxicity: Central and/or peripheral anticholinergic syndrome can occur when administered with amantadine, rimantadine, narcotic analgesics, phenothiazines and other antipsychotics (especially with high anticholinergic activity), tricyclic antidepressants, quinidine and some other antiarrhythmics, and antihistamines.
Interaction with Food
Interaction with Disease
FAQs about Trihexyphenidyl
Ques : Is Trihexyphenidyl a narcotic? Can I get high after taking Trihexyphenidyl?
Ans : No, Trihexyphenidyl is not a narcotic. However, its hallucinogenic and euphoriant properties may make the people abuse its use.
Ques : Does Trihexyphenidyl make you drowsy?
Ans : Yes, Trihexyphenidyl may cause drowsiness in some cases. Some people may even experience difficulty in falling asleep. Do not drive or operate heavy machinery when you experience drowsiness or if it causes blurring of vision, dizziness, mild nausea and mental confusion.
Ques : Does Trihexyphenidyl cause weight gain?
Ans : Yes, Trihexyphenidyl may cause weight gain. If you are concerned about your weight gain, consult a dietitian for a diet plan, exercise regularly, and eat a healthy and nutritious diet.
References
Trihexyphenidyl-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:
https://druginfo.nlm.nih.gov/drugportal/name/trihexyphenidyl
Trihexyphenidyl-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:
https://go.drugbank.com/drugs/DB00376
TRIHEXYPHENIDYL tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:
https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=TRIHEXYPHENIDYL
Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
Table of content
Ask a free question
Get FREE multiple opinions from Doctors