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Overview

Valprol Syrup

Manufacturer :  Intas Pharmaceuticals Ltd
Medicine Composition :  Sodium Valproate
Prescription vs OTC : Prescription by Doctor required

About Valprol Syrup

Valprol Syrup is a drug that aids in the control of seizures in patients who suffer from epilepsy. The drug is an anticonvulsant, and effectively increases a certain type of brain chemical that control some seizures. The drug may also be used to treat other conditions as per the doctor’s guidance.

Valprol Syrup is meant for oral consumption and can be taken before or with a meal. It is generally advised that the drug should not be taken with carbonated drinks, as irritation in the throat may occur. The dosage of the drug is primarily dependent on the patient’s age, health, weight and severity of the condition. In case you are taking Valprol Syrup to control seizures do not stop it suddenly. It is advised that the drug should be discontinued gradually, so as to prevent any complications.

Valprol Syrup use can lead to some side effects which include- dizziness, hair loss, tremor, diarrhea, changed in weight and blurred or double vision. These side effects stop gradually, but in case any of them continue or tend to worsen seek medical help immediately. A few patients may also experience mood swings and undergo depression resulting in suicidal thoughts. In this case family members should be well aware of such a side effect to take care of the patient. In case of over dosage of the drug seek immediate medical help. Symptoms of over dosage can include coma, irregular heart rate and extreme drowsiness.

In case of adults the doctor may prescribe a dosage ranging from 1000mg to 2000mg on a daily bases. Very low doses of Valprol Syrup are prescribed to children that may vary from 25mg to 30mg. An allergic reaction is very rare to this drug but may occur, resulting in a rash or chest pain along with shortness of breath. Seek medical help in this case.

    What are the uses of Valprol Syrup

    • Epilepsy

      Valprol Syrup treats Epilepsy which is a brain disorder that causes repeated seizures. Uncontrolled jerking movements and loss of consciousness are some of the symptoms of Epilepsy.

    • Mania

      Valprol Syrup treats mania which is a mental disorder characterized by hyperactivity and racing thoughts.

    • Migraine Prophylaxis

      It helps in treating prophylaxis in migraine headaches characterized by severe headache, eye pain, nausea, and vomiting.

    What are the contraindications of Valprol Syrup ?

    • Allergy

      Do not take this medication if you have a known allergy to Valprol Syrup.

    • Liver Disease

      Do not take if you have any liver injury or a family history of liver injury.

    • Urea Cycle Disorders

      Do not use in patients with urea cycle disorder (high ammonium levels in the blood) or family history of urea cycle disorder.

    • Mitochondrial Disorders

      Do not use in patients and in children who are suspected to have the mitochondrial disorder (POLG e.g Alpers-Huttenlocher Syndrome).

    What are the side effects of Valprol Syrup ?

    Key highlights of Valprol Syrup

    • How long is the duration of effect?

      The effect of this syrup lasts for an average duration of 24 hours.

    • What is the onset of action?

      The peak effect of Valprol Syrup can be observed in 2 hours.

    • Are there any pregnancy warnings?

      This syrup is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendency has been reported

    • Are there any breast-feeding warnings?

      Valprol Syrup is recommended only if clearly needed when no safer alternative is available. Monitoring of undesired effects like discoloration of eyes and skin is necessary.

    What are the substitutes for Valprol Syrup ?

    Below is the list of medicines, which have the same composition, strength and form as Valprol Syrup , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Valprol Syrup, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    How does this medication work?

    Valprol Syrup belongs to the class anticonvulsants. it works by increasing the levels of neurotransmitter GABA and inhibits sodium and calcium channels thus it reduces the excitation of the brain cells.

      What are the interactions of Valprol Syrup ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Alcohol

        Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
      • Interaction with Medicine

        Lamotrigine

        Valprol Syrup may increase the concentration of lamotrigine and can cause serious skin reactions. Frequent monitoring of undesired effects like skin rash, seizures, tremors is necessary. Suitable dose adjustments or an alternate medicine should be considered based under the doctor's supervision.

        Metoclopramide

        Use of Valprol Syrup with metoclopramide should be avoided if possible. Do not operate heavy machinery if you are using these medicines. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition under the doctor's supervision.

        Warfarin

        Valprol Syrup should be given with caution in patients with warfarin or other anticoagulants as this combination may increase the risk of bleeding. Frequent monitoring of blood cells count and prothrombin time is necessary. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition under the doctor's supervision.

        Ethinyl Estradiol

        The desired effect of Valprol Syrup will not be observed if taken with oral contraceptives. Inform the doctor if you are receiving either of the medications. Monitoring of behavior changes and seizures are necessary. An alternate medicine should be considered based on the clinical condition of the under the doctor's supervision.

        Imipenem

        Use of these medicines is not recommended as it increases the concentration of Valprol Syrup. An alternate medicine should be considered based on the clinical condition under the doctor's supervision.
      • Interaction with Disease

        Depression

        Valprol Syrup should be given with caution in the patients with depression and suicidal thoughts. Frequent monitoring of depression symptoms is necessary. Dose adjustments are to be made based on the outcomes in the patient.

        Liver Disease

        Valprol Syrup is not recommended in patients with liver injury or a family history of liver injury. This risk is more in children less than 2 years of age. Liver function tests are to be performed before starting the treatment. Discontinue the medicine if any abnormality is identified.
      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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