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Overview

Xalipat 100 MG Injection

Manufacturer :  Khandelwal Laboratories Ltd
Medicine Composition :  Oxaliplatin
Prescription vs OTC : Prescription by Doctor required

About Xalipat 100 MG Injection

Xalipat 100 MG Injection is usually administered to treat advanced stages of colon and rectal cancer. It is generally combined with other medicines as well. It works by destroying the malignant cells and stunting the growth of tumors.

Xalipat 100 MG Injection shouldn’t be administered if one is allergic to any platinum products such as carboplatin and cisplatin, is suffering from lung disorders such as interstitial lung diseases and pulmonary fibrosis and if you are about to administer palifermin within a day of the usage of Xalipat 100 MG Injection.

The usage of Xalipat 100 MG Injection can be tricky under conditions such as pregnancy or during breastfeeding, if you are using any prescription or OTC medications, herbal preparations and other dietary supplements or if one is allergic to certain foods and medicines.

Other risk factors include a personal history of breathing and lung disorders, liver disorders, kidney diseases, bone marrow issues or other nerve disorders.

Xalipat 100 MG Injection should not be used in conjunction with anticoagulants because that just increases the risks of bleeding and palifermin because the mouth sores might then persist for a longer period of time.

This drug can result in side effects such as blurred vision, temporary loss of vision, balance problems, fatigue, dizziness, etc. If diarrhea and vomiting occur as well, you should hydrate yourself sufficiently in order to avoid dehydration. Prolonged usage of Xalipat 100 MG Injection can often result in a decrease in the platelet count in the blood. Avoid activities that may cause injuries or bruising. Report to your physician if you notice dark or bloody stools. Usage of this drug can take a toll on the body’s immunity as well. Don’t go for any vaccination while this drug is being administered. Problems such as troubled breathing and dry coughs must be reported without any ado. Xalipat 100 MG Injection can also result in a burning, stinging sensation of your extremities and the region around the throat and mouth. A feeling of tightness in the jaws, pain in the eyes and the joints and angina could be rare but severe side effects of this drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the uses of Xalipat 100 MG Injection

    • Colorectal Cancer

      Xalipat 100 MG Injection is used in the treatment of cancer that affects the large intestine of the digestive system.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the contraindications of Xalipat 100 MG Injection ?

    • Allergy

      Not recommended in patients with known allergy to Xalipat 100 MG Injection or other platinum-containing compounds.

    • Severe Myelosuppression

      Not recommended in patients with low white blood cell and platelet count.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the side effects of Xalipat 100 MG Injection ?

    • Burning Or Tingling Sensation Of Hands And Feet

    • Cough

    • Fever

    • Low Wbc Count

    • Mouth Ulcers

    • Loss Of Appetite

    • Skin Rash

    • Nausea Or Vomiting

    • Swelling Of Eyelids, Face, Lips

    • Acid Or Sour Stomach

    • Sneezing

    • Stomach Discomfort And Pain

    • Running Nose

    • Change In Taste

    • Hair Loss

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Key highlights of Xalipat 100 MG Injection

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 30 to 45 days.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 2 hours after intravenous injection.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended in breastfeeding women.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the substitutes for Xalipat 100 MG Injection ?

    Below is the list of medicines, which have the same composition, strength and form as Xalipat 100 MG Injection , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Where is the Xalipat 100 MG Injection approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    How does this medication work?

    This medicine works by stopping the growth of cancer cells by inhibiting DNA synthesis. This is achieved by producing intrastrand and interstrand cross-links in DNA.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

      What are the interactions of Xalipat 100 MG Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Clozapine

        These medicines may further lower the white blood cell count if received together. Any symptoms of fever, diarrhea, sore throat, chills should be informed to the doctor. Close monitoring of blood cell count is necessary. An alternate medicine should be considered based on the clinical condition.

        Vancomycin

        These medicines may increase the risk of kidney injury and hearing loss if taken together. Report to the doctor if you experience any symptoms of hearing loss, ringing in the ears, weight gain, irregular urine frequency. An alternate class of medicine should be considered based on the clinical condition.

        Atorvastatin

        These medicines may increase the risk of nerve damage if given together. Any symptoms of numbness, tingling or burning sensation in feet, hands should be informed to the doctor. An alternate medicine should be considered based on the clinical condition.

        Live vaccines

        You may be at the risk of developing infections if these medicines are taken together. Inform the doctor if you had received either of these medicines. Your doctor may postpone therapy based on the condition.
      • Interaction with Disease

        Arrhythmia

        This medicine should be used with caution in patients with heart diseases due to the increase in the risk of irregular heart rhythm. Monitor the potassium levels, which may exacerbate the condition. Any symptoms of heart palpitation should be reported to the doctor.

        Lung Injury

        This medicine may cause rare but fatal lung injury. Inform the doctor if you have any lung disease. Any symptoms of difficulty in breathing, non-productive cough should be reported to the doctor. Discontinue the treatment until the exact cause is identified.
      • Interaction with Food

        Food

        Information not available.

      References

      • Oxaliplatin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/oxaliplatin

      • Oxaliplatin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00526

      • OXALIPLATIN injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=OXALIPLATIN

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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