Zerograin-Plus Tablet

Zerograin is a drug that is used to prevent migraine attacks. It is used to lower the frequency of the attacks and in some instances the severity. This medication is grouped under a category of non-selective drugs called calcium antagonist along with dopamine antagonist and COX inhibitor.

The common side effects of this medication are drowsiness, weight gain, nausea, heartburn, anxiety and depression (as seen in adults). In case, effects persist for longer duration's inform your physician.

If you miss a dose take it as soon as possible. However, if it already time for your next dose, do not club doses but skip the previous one. Ensure to keep these tablets in a cool and dry place (between 15 to 30 degrees C) and out of the reach of children. If you happen to overdose contact your doctor right away.

• Migraine

• Prevention Of Vertigo

• Allergy

• Parkinson's Disease

• Dryness In Mouth

• Tingling Or Numbness Of The Hands And Feet

• Swelling Of Face, Lips, Eyelids, Tongue, Hands And Feet

• Increased Appetite

• Blocked Or Runny Nose

• Is It safe with alcohol?

  Taking Domperidone+Flunarizine+Paracetamol / Acetaminophen with alcohol can cause liver damage.

• Are there any pregnancy warnings?

  This medicine is extremely unsafe to be used during pregnancy. Studies carried out on humans and animals have shown significant adverse effects on the fetus. Doctor consultation is recommended in such cases.

• Are there any breast-feeding warnings?

  No information is available on the use of this medication during lactation. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Zerograin may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

• Does this affect kidney function?

  This medication is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Zerograin may not be needed in these patients.

• Does this affect liver function?

  This medication should be used with caution in patients with liver disease. Please consult your doctor.
  However, the use of this tablet is not recommended in patients with severe liver disease and active liver disease.

Below is the list of medicines, which have the same composition, strength and form as Zerograin-Plus Tablet , and hence can be used as its substitute.

• Blomig P 10 mg/5 mg/325 mg Tablet

  Klar Sehen Pvt Ltd

• Are there any missed dose instructions?

  Skip the missed dose and resume with the next scheduled dose at the right time. The dose should not get doubled in an attempt to make up for the missed dose.

• Are there any overdose instructions?

  In case of an overdose, a doctor should be consulted immediately. The overdose symptoms are restlessness, confusion and dizziness.

Zerograin attaches to the dopaminergic receptors without causing any release of the chemical dopamine. Facilitates gastric emptying and decreases small bowel transit time. It also works by blocking the influx of calcium inside the cells. This medication also blocks certain other specific neurotransmitters and caused relaxation of blood vessels. Lastly, it selectively inhibits enzyme function in the brain which allows it to treat pain and fever. Activates certain receptors in the brain that inhibit pain signals too.

• Ques : What is Zerograin-Plus Tablet?

  Ans : This is a medication which has Domperidone, Flunarizine, and Paracetamol as active elements present in it. This medicine performs its action by obstructing the dopamine receptors, obstructing the entry of calcium through calcium channels, increases the blood flow across the skin, heat loss and sweating.

• Ques : What are the uses of Zerograin-Plus Tablet?

  Ans : This is a medication, which is used for the treatment and prevention from conditions such as Migraine, Headache, Cephalalgia, Ear pain, Toothache, Migraine attacks, Cold, Fever, menstrual pain, Cerebrovascular disorders, etc.

• Ques : What are the Side Effects of Zerograin-Plus Tablet?

  Ans : This is a medication which has some commonly reported side effects such as Cephalalgia, Increased in weight, Headache, Somnolence, Akathisia, Diarrhea, Rash, Pruritus, Breast enlargement, Breast tenderness, Galactorrhoea, etc.

• Ques : What are the instructions for storage and disposal Zerograin-Plus Tablet?

  Ans : Store this medication in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

• Ques : How long do I need to use Zerograin-Plus Tablet before I see improvement of my conditions?

  Ans : It is a medicine which takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

• Ques : What are the contraindications to Zerograin-Plus Tablet?

  Ans : Contraindication to Zerograin. In addition, this medication should not be used if you have the following conditions such as Breastfeeding, Co-administration with potent CYP3A4 inhibitors, Congestive heart failure, Depression, etc.

• Ques : Is Zerograin-Plus Tablet safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

• Ques : Will Zerograin-Plus Tablet be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of this medicine can lead to increased chances of side effects such as Cephalalgia, Increased in weight, Headache, Somnolence, Akathisia, Diarrhea, Rash, Pruritus, Breast enlargement, Breast tenderness, etc.

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/rn/57808-66-9

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 10 May 2019]. Available from:

  https://www.drugbank.ca/drugs/DB01184

• Flunarizine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 26 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/flunarizine

• Flunarizine- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 25 April 2019]. Available from:

  https://www.drugbank.ca/drugs/DB04841

• Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/paracetamol

• Acetaminophen- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 10 May 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00316