Zocef 500 MG Tablet

Zocef 500 MG Tablet is used for the treatment of susceptible infections of the lower respiratory tract, otitis media, urinary tract, skin and soft tissue, bone and joint, sepsis and gonorrhoea. It is an antibiotic drug that a part of the class of medicines called cephalosporin.

This broad-spectrum antibiotic is useful in treating a wide variety of infections that are caused by bacteria. This medicine specifically used for the treatment of infections caused by staphylococci, group B streptococci, H. influenzae (type A and B), E. coli, Enterobacter, Salmonella, and Klebsiella.

It is used in the treatment of conditions such as acute or chronic bronchitis, tonsillitis, Lyme disease, Chlamydia, gonorrhea, syphilis, pneumonia, laryngitis, sinusitis and urinary tract infections. This drug is also used to treat bacterial infections of the throat, cervix, pelvis, urethra, skin, middle ear and nasal passage.

Zocef 500 MG Tablet works by creating a hostile environment for the bacteria to survive. It damages the cell walls of bacteria, prevents the growth of bacteria and therefore eliminates the bacterial infection.

Zocef 500 MG Tablet intervenes in the bacteria’s process of forming cell walls. The cell walls of the bacteria are essential for their survival. The bacterial cell walls protect the contents of the cell from leaking out. This antibiotic damages the bond that keeps the cell wall in one piece.

Therefore, Zocef 500 MG Tablet causes holes to appear in the cell wall, making it impossible for the bacteria to survive. In this way, by destroying bacteria and inhibiting the reproduction of bacterial cells, the antibiotic is effective in eliminating bacterial infections.

The risk of side effects increases if you take this medication while suffering from conditions like liver disorders, kidney problems, heart conditions, allergies, gastrointestinal diseases, phenylketonuria and diarrhoea caused by Clostridium difficile.

Since it might lead to negative reactions for these patients, you should consult with your doctor before starting a prescription of Zocef 500 MG Tablet, if you are a:

• Pregnant women
• Breastfeeding mother
• Children

You could have an allergic reaction from taking Zocef 500 MG Tablet. An allergy to this anti-biotic will result in symptoms such as hives, rashes, swelling of the tongue, throat, face, hands or feet, itchiness and difficulty in breathing. If you experience any of these symptoms, you should discontinue the usage of this drug and contact a medical health professional immediately.

After acute overdose, most agents cause only nausea, vomiting, and diarrhea, although neuromuscular hypersensitivity and seizures are possible, especially in patients with renal insufficiency; many beta-lactam antibiotics have the potential to cause neuromuscular hyperirritability or seizures.

Hemodialysis may be helpful to aid in the removal of the drug from the blood but not usually indicated, otherwise most treatment is supportive or symptom directed following GI decontamination.

Take as directed, at regular intervals around-the-clock (with or without food). Chilling oral suspension improves flavor (do not freeze). Complete full course of medication, even if you feel better. Drink 2-3 L fluid/day. If diarrhea occurs, yogurt or buttermilk may help.

• Bacterial Infections

• Lower Respiratory Tract Infection

• Otitis Media (Infection Of Ear)

• Urinary Tract Infection

• Skin And Soft Tissue Infections

• Bone And Joint Infections

• Sepsis

• Gonorrhea And Associated Infections

• Allergy

• Tendinitis Or Tendon Rupture

• Myasthenia Gravis

• Low Hemoglobin

• Liver Transaminases Increased

• Thrombophlebitis

• Anaphylaxis

• Dizziness

• Fever

• Headache

• Rash

• Nausea

• Vomiting

• Diarrhoea

• Colitis

• Neutropenia

• Increased Creatinine Level In Blood

• Seizures

• Angioedema

• Cholestasis

• How long is the duration of effect?

  The effect of this medication lasts for a duration of 8 hours.

• What is the onset of action?

  The effect can be observed within 2 to 3 hours of administration of the dose.

• Are there any pregnancy warnings?

  Pregnant women should not use this medication. Consult your doctor before using this medication. Potential benefits and risks involved should be given due consideration before administration.

• Is it habit forming?

  No, it does not contain habit forming tendencies.

• Are there any breast-feeding warnings?

  Women who are breastfeeding should not use this medication as it can cause side effects for the baby. Consult your doctor before taking this medication. Avoid breastfeeding for about 3 to 4 hours to decrease the infant's risk exposure. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

• Is It safe with alcohol?

  Consumption of alcohol with this medicine does not cause any harmful adverse effects.

• Is it safe to drive while on this medicine?

  As this medicine is only prescribed to the patient who are hospitalized. Thus it is not relevant.

• Does this affect kidney function?

  Only limited information is available regarding its use in patient with kidney disease. Kindly consult your doctor before taking this medication.

• Does this affect liver function?

  Only limited information is available regarding its use in patient with liver disease. Kindly consult your doctor before taking this medication.

Below is the list of medicines, which have the same composition, strength and form as Zocef 500 MG Tablet , and hence can be used as its substitute.

• Kefstar 500 MG Tablet

  Wockhardt Ltd

• Ceftum 500 MG Tablet

  Glaxosmithkline Pharmaceuticals Ltd

• Covatil 500 MG Tablet

  Macleods Pharmaceuticals Pvt.Ltd

• Xorimax 500 MG Tablet

  Novartis India Ltd

• Seazox 500 MG Tablet

  Orchid Chemicals & Pharmaceuticals Ltd

• Are there any missed dose instructions?

  Missed dose should be taken as soon as you remember.

• Are there any overdose instructions?

  Doctor consultation is recommended if an overdose is suspected.

Belonging to the second generation cephalosporins, the medicine works as a bactericidal by inhibiting the bacterial cell wall synthesis by binding to the penicillin-binding proteins which would inhibit the growth and multiplication of bacteria.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  This medication do not interact with alcohol. Doctor consultation is recommended.

• Interaction with Lab Test

  Inform your doctor beforehand any of the pathological testing, as this medication leads to positive direct Coombs', false-positive urinary glucose test using cupric sulfate (Benedict's solution, Clinitest®, Fehling's solution), false-positive serum or urine creatinine with Jaffé reaction.

• Interaction with Medicine

  • This medication is known to interact with Amikacin, Chloramphenicol, Ethinyl Estradiol, Cholera Vaccine and Furosemide.
  • Increased effect: High-dose probenecid decreases the clearance
  • Increased toxicity: Aminoglycosides increase the nephrotoxic potential

• Interaction with Disease

  Modify dosage in patients with severe renal impairment, prolonged use may result in superinfection; use with caution in patients with a history of penicillin allergy, especially IgE-mediated reactions (eg, anaphylaxis, urticaria); may cause antibiotic-associated colitis or colitis secondary to C. difficile.

• Interaction with Food

  This medicine may be taken with food, however, bioavailability is increased with food.

• Ques : How long does Zocef 500 MG Tablet take to work?

  Ans : The time taken by Zocef 500 MG Tablet to show its action depends on the severity of the patient's condition. It also depends on the type of infection. However, in general, it takes about 48-72 hours.

• Ques : Can you drink alcohol on Zocef 500 MG Tablet?

  Ans : The consumption of alcohol should be limited during the course of medication as it can cause severe interactions that might prove fatal for some patients.

• Ques : How long should you take Zocef 500 MG Tablet?

  Ans : You must take this medication for at least one week to notice the improvement. The duration of treatment usually varies within 5 to 10 days depending on the medical condition of the patient.

• Ques : Can Zocef 500 MG Tablet be taken on an empty stomach?

  Ans : This medication should not be consumed on an empty stomach as it can cause problems related to the stomach. You must only take it after food to enhance the effectiveness of the drug to cure the infection.

• Ques : Can Zocef 500 MG Tablet treat UTI?

  Ans : This medication can be helpful in managing urinary tract infection (UTI). However, it is effective only against uncomplicated cases of UTIs.

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  https://druginfo.nlm.nih.gov/drugportal/rn/55268-75-2

• CEFUROXIME AXETIL tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2021 [Cited 25 Nov 2021]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=faef39e9-d793-4191-a728-310f6fab759d

• Zinacef- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 25 Nov 2021]. Available from:

  https://www.medicines.org.uk/emc/product/953/smpc