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Overview

Zostum 1.5Gm Injection

Manufacturer :  Zuventus Healthcare Ltd
Medicine Composition :  Cefoperazone, Sulbactam
Prescription vs OTC : Prescription by Doctor not required

About Zostum 1.5Gm Injection

Zostum injection is a combination of cephalosporin antibiotic and penicillin antibiotic. It is used to treat bacterial infections caused by Pseudomonas. These are antibiotic-resistant bacterial infections that do not react with other antibiotic medications. Zostum works by interfering with the bacterial cell wall synthesis in the body, which eventually kills the bacteria. The correct dosage is determined based on body weight, age, medical condition, etc.

Aside from its intended effect, the injection can lead to other side effects, such as diarrhoea, decreased white blood cells, severe allergic reaction, neutropenia, vomiting, nausea, skin rash, itching of skin and low platelet count.

The medicine has contraindications to certain diseases, such as renal impairment, colitis and gastrointestinal conditions. Alcohol addictions and liver disease are some other contraindications for the drug. Therefore, it is vital to let the doctor know your medical history, before the injection is administered.

The medicine helps treat infections in the bone, joints, urinary tract, respiratory tract and infections in the soft tissues of the body, such as skin. This drug may be used in conjunction with other drugs to treat bacterial infections.

    What are the uses of Zostum 1.5Gm Injection

    • Bacterial Infections

    What are the contraindications of Zostum 1.5Gm Injection ?

    • Hypersensitivity

    What are the side effects of Zostum 1.5Gm Injection ?

    Key highlights of Zostum 1.5Gm Injection

    • Is It safe with alcohol?

      You should avoid alcohol consumption for 48 to 72 hours post the administration of the drug. Alcohol may lead to severe headache, palpitation, severe vomiting, sweating, increased heart rate and difficulty in breathing.

    • Are there any pregnancy warnings?

      Pregnant women should avoid using the medicine. However, if the benefits outweigh the risks, your doctor may prescribe it to you. Under all other circumstances, avoid the medicine to ensure safety for you and your baby.

    • Are there any breast-feeding warnings?

      Breast-feeding women should avoid the medicine, as it may pose a risk to the newborn’s health. You should only use the drug if the doctor recommends it and its benefits are greater than the risks it poses.

    • Is it safe to drive while on this medicine?

      Avoid driving if you experience side effects from the drug, such as sleepiness and drowsiness. However, in the absence of these side effects, it may be safe to drive and operate heavy machinery.

    • Does this affect kidney function?

      If you suffer from kidney diseases or have a history of such disorders, you should use Zostum 1.5 g with extreme caution, as the drug can adversely affect the kidneys. Speak with the doctor to find alternative medicine or adjust the dosage to reflect your medical history.

    • Does this affect liver function?

      The medicine has the propensity to affect liver health adversely. If you have prior history of liver damage, speak to your doctor about it. He may adjust the dosage of the medication to ensure that the condition of the liver does not deteriorate further.

    • What is the onset of action?

      The effects of the medicine starts quite soon post the intravenous or intramuscular administration. However, the onset of action may vary based on the physical parameters of the patient.

    • Is it habit forming?

      The medicine does not have any habit-forming properties, but you should stick to the doctor’s recommendation to prevent unforeseen side effects and dependency.

    What are the substitutes for Zostum 1.5Gm Injection ?

    Below is the list of medicines, which have the same composition, strength and form as Zostum 1.5Gm Injection , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The injection is administered by a medical practitioner, which makes it quite unlikely that you would ever miss a dose.

    • Are there any overdose instructions?

      A doctor or a nurse administers the Zostum 1.5 g. Therefore, the risk of overdose is quite low. However, in case there is an overdose, emergency medical attention may be needed to prevent side effects

    How does this medication work?

    Zostum 1.5Gm Injection is a kind of antibiotic that helps deal with bacterial infection. The medication prevents the synthesis of the bacterial cell walls, as it binds to the penicillin-binding proteins. The drug stops the last stage of the bacterial cell wall formation. It also works as a beta-lactamase inhibitor by binding to beta-lactamase enzyme produced by bacterial cells, which in turn inhibits its enzymatic action and prevents beta-lactam antibiotics from being metabolised by the enzyme.

      What are the interactions of Zostum 1.5Gm Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        The exact interaction between alcohol and the drug is unknown. However, doctors recommend suggest staying away from alcohol 48 to 72 hours post the administration of the drug. Drinking during this time may lead to breathing issues, drowsiness, abdominal pain and other side effects.

      • Interaction with Medicine

        Keep away from medicine, such as loop diuretics, probenecid, anticoagulants and aminoglycoside antibiotics.

      • Interaction with Disease

        People who sufer from kidney disorders or have a history of similar diseases need to use Zostum 1.5 g with extreme caution, as the drug may lead to damage to the kidneys. Monitoring of kidney function along with adjustment of dosage is recommended in case of renal impairments.

      • Interaction with Food

        The medicine does not react with food in general. Therefore, you do not need to alter your diet while being on the drug.

      FAQs about Zostum 1.5Gm Injection

      • Ques : What is Zostum 1 5gm injection?

        Ans : Zostum injection is a medication which has Cefoperazone and Sulbactam as active elements present in it. This injection performs its action by avoiding destruction antibiotics, from chemicals released from bacteria, restricting bacterial cell wall synthesis. This injection is used to treat conditions such as Chronic respiratory tract infections, Infections of the respiratory tract, Intra Abdominal infections, Gynecological infections, Skin or soft tissue infections, Surgical infections, Peritonitis, Intra-abdominal infections, Endometritis, Pelvic inflammatory disease, Respiratory tract infections, etc.

      • Ques : What is the use of Zostum 1 5gm injection?

        Ans : Zostum is a medication, which is used for the treatment and prevention from conditions and symptoms of diseases like Urinary tract infection, Skin and soft tissue infection, Bacterial infections, Septicemia, Intraabdominal infections, Infections of the urinary tract, Chronic respiratory tract infections, Infections of the respiratory tract. Apart from these, it can also be used to treat conditions like Intra Abdominal infections, Gynecological infections, Skin or soft tissue infections, Surgical infections, Peritonitis, Intra-abdominal infections, Endometritis, Pelvic inflammatory disease, Respiratory tract infections, etc. The patient should inform the doctor about any ongoing medications and treatment before using Zostum to avoid undesirable effects.

      • Ques : What are the side effects of Zostum 1 5gm injection?

        Ans : Zostum injection is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of Zostum injection which are as follows: Diarrhea, Pain at a site of injection, Rash, Inflammation of a vein caused by blood clots, Allergic reactions, Neutropenia, Nausea, Vomiting. It is a list of possible side-effects which may occur due to the constituting ingredients of this injection.

      • Ques : Can Zostum Injection be used for urinary tract infection and skin and soft tissue infection?

        Ans : Yes, This injection can be used for the conditions such as urinary tract infection and skin and soft tissue infection. Do not use Zostum for above-mentioned conditions without consulting first with your doctor. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : How long do I need to use Zostum 1.5gm injection before I see improvement in my condition?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition. So please consult your doctor.

      • Ques : At what frequency do I need to use Zostum 1.5gm injection?

        Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

      • Ques : Should I use Zostum 1.5gm injection empty stomach, before food or after food?

        Ans : This medication should be applied by the doctor himself. It is recommended not to apply it, on your own. The action of salts involved in the medication, do not depend whether taking it pre-meal or post-meal, though It is advised to consult a doctor about your meal timings.

      • Ques : What are the instructions for the storage and disposal of Zostum 1.5gm injection?

        Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

      References

      • Sulbactam- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/68373-14-8

      • Cefoperazone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/cefoperazone

      • Cefoperazone- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 27 April 2019]. Available from:

        https://www.drugbank.ca/drugs/DB01329

      • Sulbactam- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 27 April 2019]. Available from:

        https://www.drugbank.ca/drugs/DB09324

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Rohini DhillonMBA( CHA), MBBS, PGDMCHGeneral Physician
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