Zyloric 100 MG Tablet

Zyloric 100 MG Tablet is helpful in prevention of attack of gouty arthritis and nephropathy; also used to treat secondary hyperuricemia which may occur during treatment of tumors or leukemia, and to prevent recurrent calcium oxalate calculi.

You should not take this drug if you are allergic to it. This medicine belongs to a class of drugs called xanthine oxidase inhibitors. Increased uric acid levels are the major cause for gout and kidney problems. Tell your doctor if you are:

• Pregnant or planning to conceive.
• Breastfeeding a baby.
• Suffering from kidney disease, liver disease, diabetes, high blood pressure.
• Receiving any chemotherapy.

Stop using this medicine and call your doctor at once if you experience serious side effects like:

• fever, sore throat, and headache with severe rashes on the skin.
• urinating less than usual or not at all.
• pain or bleeding when you urinate.
• nausea, upper stomach pain, weight loss, itching, loss of appetite, dark urine, clay-colored stools, body pain, yellowing of the skin or eyes.
• easy bruising, unusual bleeding of nose, mouth, vagina, or rectum.

Take as directed. Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake) to avoid possible adverse renal problems. While using this medication, do not use alcohol, other prescription or OTC medications, or vitamin substances without consulting prescriber.

You may experience drowsiness (use caution when driving or engaging in tasks requiring alertness until response to drug is known); nausea, vomiting, or heartburn (small frequent meals, frequent mouth care, chewing gum, or sucking lozenges may help); hair loss (reversible).

Report skin rash or lesions; painful urination or blood in urine or stool; unresolved nausea or vomiting; numbness of extremities; pain or irritation of the eyes; swelling of lips, mouth, or tongue; unusual fatigue; easy bruising or bleeding; yellowing of skin or eyes; or any change in color of urine or stool.

• Gout

• Hyperuricemia Secondary To Chemotherapy

• Calcium Oxalate Calculi With Hyperuricosuria

• Allergy

• Pregnancy

• Joint Pain

• Skin Rash

• Nausea Or Vomiting

• Stomach Pain

• Dizziness

• Depression

• Loss Of Appetite

• Change In Taste

• Dyspepsia

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 24 hours.

• What is the onset of action?

  The effect of this tablet can be observed in 2 to 3 days.

• Are there any pregnancy warnings?

  This medicine should not be consumed during pregnancy unless necessary. Consulting a doctor is mandatory to discuss the benefits and risks before taking the medicine.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is known to excreted in breast milk. It is not recommended in breastfeeding women unless necessary.

• Is It safe with alcohol?

  Caution must be taken if consuming alcohol while taking this medicine.

• Is it safe to drive while on this medicine?

  This medicine might affect the alertness of the patient thus driving must be avoided if you feel any side effects alerting the same.

• Does this affect kidney function?

  Caution must be taken while using this medicine in patients with kidney disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

• Does this affect liver function?

  Caution must be taken while using this medicine in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Zyloric 100 MG Tablet , and hence can be used as its substitute.

• Alrik 100 MG Tablet

  Cipla Ltd

• Gudloric 100 MG Tablet

  Mankind Pharmaceuticals Ltd

• Ryloric 100 MG Tablet

  Ranbaxy Laboratories Ltd

• Uritas 100 MG Tablet

  Intas Pharmaceuticals Ltd

• Zyprinol 100 MG Tablet

  Zydus Cadila

• Missed Dose instructions

  Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of overdose.

Allopurinol belongs to the class xanthine oxidase inhibitor. It works by inhibiting xanthine oxidase enzyme thus inhibits the conversion of hypoxanthine to xanthine to uric acid without affecting the enzymes that involved in purine and pyrimidine synthesis.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  • Inhibits metabolism of azathioprine and mercaptopurine (reduce to 1/3 or 1/4 of usual dose).
  • Use with ampicillin or amoxicillin may increase the incidence of skin rash.
  • Urinary acidification with large amounts of vitamin C may increase kidney stone formation.
  • Thiazide diuretics enhance toxicity, monitor renal function; thiazide diuretics and captopril (possibly other ACE inhibitors) may increase risk of hypersensitivity.
  • Vidarabine neurotoxicity may be enhanced.
  • Cyclosporine levels may be increased.
  • Hepatic iron uptake may be increased with iron supplements.
  • Allopurinol prolongs half-life of oral anticoagulants; allopurinol increases serum half-life of theophylline; allopurinol may compete for excretion in renal tubule with chlorpropamide and increases chlorpropamide's serum half-life.

• Interaction with Food

  Should be administered after meals with plenty of fluid.

• Interaction with Disease

  Do not use to treat asymptomatic hyperuricemia. Discontinue at first signs of rash; reduce dosage in renal insufficiency, reinstate with caution in patients who have had a previous mild allergic reaction, use with caution in children; monitor liver function and complete blood counts before initiating therapy and periodically during therapy, use with caution in patients taking diuretics concurrently. Risk of skin rash may be increased in patients receiving amoxicillin or ampicillin. The risk of hypersensitivity may be increased in patients receiving thiazides, and possibly ACE inhibitors.

• Ques : What is zyloric 100 mg tablet?

  Ans : Zyloric 100 mg tablet is a medication which has Allopurinol as an active ingredient present in it.

• Ques : What are the uses of zyloric 100 mg tablet?

  Ans : Zyloric 100 mg tablet is used for the treatment and prevention from conditions and symptoms of diseases like Chronic gout, Leukemia, Leukaemia, and Uric Acid disorders.

• Ques : What are the Side Effects of zyloric 100 mg tablet?

  Ans : The side effects include Diarrhea, Nausea, and acute gout. Apart from these, using this medicine may further lead to Skin and Maculopapular rashes.

• Ques : What are the instructions for storage and disposal zyloric 100 mg tablet?

  Ans : Store Zyloric 100 MG Tablet away from direct light and heat at room temperature. Keep it out of rhea from children and pets.

• Ques : How long do I need to use Zyloric 100 MG Tablet before I see improvement in my condition?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 1 week. Take Zyloric 100 MG Tablet as prescribed by your doctor.

• Ques : At what frequency do I need to use Zyloric 100 MG Tablet?

  Ans : This medication is generally used once or twice a day. It is advised to consult your doctor before usage, as the frequency also depends on the patient's condition.

• Ques : Should I use Zyloric 100 MG Tablet empty stomach, before food or after food?

  Ans : Zyloric 100 MG Tablet is taken orally with a meal. Taking it on an empty stomach might cause distress.

• Ques : What is the appropriate amount of hydration with Zyloric 100 MG Tablet?

  Ans : It is important to intake at least 2 liters of water while taking this medication for the increased urine output and prevention of kidney stones.

• Ques : How does Zyloric 100 MG Tablet interact in patients with a history of bone marrow suppression?

  Ans : Zyloric 100 MG Tablet tends to decrease the production of blood cells which increases the risk of infection. Hence, a patient with bone marrow suppression should be closely monitored while taking this medication. Frequent tests should be done to notice the alteration in blood cells.

• Ques : How is Zyloric 100 MG Tablet administered?

  Ans : Zyloric 100 MG Tablet can be administered orally as well as an injection.

• Ques : How long does Zyloric 100 MG Tablet take to treat gout?

  Ans : Zyloric 100 MG Tablet may take up to 6 weeks or the effective treatment of gout. A patient may experience gout attacks in the first two weeks while taking medication.