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Overview

Zyven Od Plus 100 Mg/0.5 Mg Tablet

Manufacturer :  Zydus Cadila
Medicine Composition :  Desvenlafaxine, Clonazepam
Prescription vs OTC : Prescription by Doctor required

About Zyven Od Plus 100 Mg/0.5 Mg Tablet

Zyven Od Plus 100 Mg/0.5 Mg Tablet belongs to a group of medicines called the serotonin-norepinephrine reuptake inhibitor. It is used to treat major depression symptoms of which may include feelings of sadness, decreased energy level, loss of interest in daily activities or trouble sleeping. These symptoms last for two weeks or longer. This anti-depressant may improve your mood, energy level and feelings of well-being. It works by helping to restore the balance of serotonin and norepinephrine in the brain. Zyven Od Plus 100 Mg/0.5 Mg Tablet comes in the form of an extended-release tablet you take by mouth. This drug slowly releases into the body over time.

The possible side effects of using Zyven Od Plus 100 Mg/0.5 Mg Tablet are :

  • Seizure (convulsions)
  • Agitation, headache, hallucinations, trouble concentrating, fever, weakness, fast heart rate, overactive reflexes, nausea, memory problems, vomiting, diarrhoea, loss of coordination
  • Eye problems
  • Cough and cold, chest tightness, trouble breathing
  • Easy bruising or bleeding, blood in your urine or stools
  • Very rigid muscles, high fever, fainting, sweating, confusion, tremors
  • Severe skin reaction especially in the face or upper body

Do not take this medicine if :

  • You are allergic to any ingredient in desvenlafaxine tablets or to venlafaxine
  • You are taking or have taken linezolid or St. John's wort within the last 14 days.
  • You are taking a fenfluramine derivative, nefazodone, sibutramine, or tryptophan
  • You are taking another medicine that contains venlafaxine or desvenlafaxine

Your dosage, drug form, and how often you take the drug will depend on your age, the condition being treated, how severe your condition is, other medical conditions you have, how you react to the first dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the uses of Zyven Od Plus 100 Mg/0.5 Mg Tablet

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the contraindications of Zyven Od Plus 100 Mg/0.5 Mg Tablet ?

    • Allergy

      This medicine is not recommended for use if you have a known history of allergy to desvenlafaxine or any other component present in the medicine.

    • Monoamine oxidase inhibitors (MAOI)

      This medicine is not recommended for use while a MAOI (Rasagiline/Selegiline/methylene blue etc.) is being consumed. This medicine should be consumed at least 14 days after stopping the use of MAOI medicines.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the side effects of Zyven Od Plus 100 Mg/0.5 Mg Tablet ?

    • Suicidal Thinking And Behaviour

    • Serotonin Syndrome (Agitation, Hallucinations, Seizures, Nausea)

    • Irregular Heart Beat

    • Shaking Of Hands Or Feet

    • Dizziness

    • Chills

    • Blurred Vision

    • Nausea Or Vomiting

    • Dry Mouth

    • Constipation

    • Muscle Stiffness

    • Decrease In Libido

    • Difficulty In Passing Urine

    • Rapid Weight Loss

    • Photosensitivity

    • Ringing Or Buzzing In The Ears

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    Key highlights of Zyven Od Plus 100 Mg/0.5 Mg Tablet

    • How long is the duration of effect?

      The time duration for which this medicine remains effective is 20-25 days.

    • What is the onset of action?

      The effect of this medicine is cumulative and takes 7-8 weeks to show in most cases.

    • Are there any pregnancy warnings?

      This medicine should be used by pregnant women only when the potential benefits outweigh the risks involved. Consult your doctor before using this medicine.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for use by breastfeeding women. It is recommended to discontinue breastfeeding before starting the treatment with this medicine. Consult your doctor before using this medicine.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the substitutes for Zyven Od Plus 100 Mg/0.5 Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Zyven Od Plus 100 Mg/0.5 Mg Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      Take the missed dose as soon as you remember. If the next scheduled dose is 4 hours away, then the missed dose should be skipped.

    • Are there any overdose instructions?

      Contact a doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include agitation, hallucinations, convulsions, and nausea.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    Where is the Zyven Od Plus 100 Mg/0.5 Mg Tablet approved?

    • India

    • United States

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    How does this medication work?

    The active constituent of this medication is a metabolite of venlafaxine and works by potentiating the activity of serotonin and norepinephrine in the brain by preventing their reuptake.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

      What are the interactions of Zyven Od Plus 100 Mg/0.5 Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Ethanol

        Avoid or limit the uptake of alcohol while using this medicine. It is advised to refrain from driving vehicles and operating heavy machinery while using this medicine.
      • Interaction with Lab Test

        Test for Phencyclidine (PCP) and amphetamine

        Report the use of this medicine to the doctor if you are taking a screening test for Phencyclidine (PCP) or amphetamine. Use of this medicine may interfere with the test results.
      • Interaction with Medicine

        Linezolid

        Report the use of either of the medicines to the doctor. There must be a sufficient time gap between the use of these medicines. Your doctor may determine the best course of treatment after accessing the condition.

        Lithium

        Report the use of either of the medicines to the doctor. The risk of adverse effects is significantly high when these medicines are used together. Your doctor may determine the best course of treatment after accessing the condition.

        Sertraline

        Report the use of either of the medicines to the doctor. The risk of adverse effects is significantly high when these medicines are used together. Your doctor may determine the best course of treatment after accessing the condition.

        Warfarin

        Report the use of Warfarin or other anticoagulants to the doctor before receiving desvenlafaxine. The risk of adverse effects is significantly high in the elderly and patients with kidney or liver diseases. Your doctor may determine the best course of treatment after accessing the condition.

        Aspirin

        Report the use of Aspirin or other NSAIDs to the doctor before receiving desvenlafaxine. The risk of adverse effects is significantly high in the elderly and patients with kidney or liver diseases. Your doctor may determine the best course of treatment after accessing the condition.

        Methylene blue

        Report the use of either of the medicines to the doctor. There must be a sufficient time gap between the use of these medicines. Your doctor may determine the best course of treatment after accessing the condition.

        Indinavir

        Report the use of either of the medicine to the doctor. You may need a dose adjustment and more frequent clinical monitoring to safely use them together.

        Sumatriptan

        Report the use of either of the medicines to the doctor. The risk of adverse effects is significantly high when these medicines are used together. Your doctor may determine the best course of treatment after accessing the condition.
      • Interaction with Disease

        Kidney Disease

        This medicine should be used with caution in patients with an impaired kidney functions. Suitable dose adjustments should be made based on the serum creatinine levels for moderate to severe impairment.

        Glaucoma

        This medicine should be used with caution in patients having narrow-angle glaucoma. The symptoms of the disease might worsen if this medicine is used in such patients.

        Hypertension

        This medicine may cause an increase in the blood pressure levels and hence should be used with caution in patients with hypertension. The blood pressure level should be constantly monitored before and during the course of treatment.
      • Interaction with Food

        Food

        Information not available.

      References

      • Desvenlafaxine-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 3 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/desvenlafaxine

      • Desvenlafaxine-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 3 June 2022].Available from:

        https://go.drugbank.com/drugs/DB06700

      • DESVENLAFAXINE Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 3 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=DESVENLAFAXINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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