Af 400 MG Tablet

Af 400 MG Tablet is primarily prescribed for the treatment of hepatosplenic candidiasis and other Candida infections, cryptococcal infections and secondary prophylaxis for cryptococcal meningitis in persons with AIDS. It is also used as antifungal prophylaxis in allogeneic bone marrow transplant recipients.

This medicine belongs to the class of triazole antifungal. Af 400 MG Tablet is effectively used in the treatment of meningitis. It affects the membranes in the brain and spinal cord. This drug treats fungal infections like yeast infections in the mouth, throat, food pipe, lungs, vagina, etc.

It works by decreasing the production of ergosterol, which inhibits cell membrane formation in fungi. This drug is also preferred as a preventive medication in patients susceptible to fungal infections while undergoing chemotherapy or radiation therapy before bone marrow transplantation.

Some serious side effects that may occur and need immediate medical attention are:

• Yellowing of the skin, dark urine, light-coloured stool and itchiness of the skin, indicating liver damage
• Severe rash or peeling of the skin in patients suffering from cancer or AIDS
• Irregular or fast heart rate, palpitations, seizures or fainting, indicating Torsades de Pointes (a condition of abnormal rhythm of the heart which may cause a sudden cardiac arrest)

• Oropharyngeal Candidiasis

• Fungal Infections

• Vaginal Candidiasis

• Fungal Infections (Tinea Strains)

• Cryptococcal Meningitis

• Coccidioidomycosis

• Allergy

• Nausea

• Headache

• Skin Rash

• Dizziness

• Hypokalemia

• Decreased Appetite

• Insomnia

• Tremor

• Vertigo

• Constipation

• Dry Mouth

• Abdominal Pain

• Vomiting

• Diarrhoea

• How long is the duration of effect?

  The action of this tablet in the body lasts for up to 30 hours are administration.

• What is the onset of action?

  This medication starts is action within a couple of hours after oral use.

• Are there any pregnancy warnings?

  The tablet is not prescribed during pregnancy unless the use is undeniably necessary.

• Is it habit forming?

  This medication does not have addictive tendencies.

• Are there any breast-feeding warnings?

  Use of Af tablet during lactation is avoided unless the benefits are vast in comparison to risks.

• Is It safe with alcohol?

  Caution is advised in consuming alcohol, if you are taking this medicine. Please consult your doctor.

• Is it safe to drive while on this medicine?

  This medicine causes side effects that affect the alertness of the patients. Thus it influences the driving ability of the patient.

• Does this affect kidney function?

  Dose adjustment is needed in patients with renal impairment. Consult your doctor before taking Af 400 MG Tablet.

• Does this affect liver function?

  No relevant information available. Consult your doctor before taking Af 400 MG Tablet.

Below is the list of medicines, which have the same composition, strength and form as Af 400 MG Tablet , and hence can be used as its substitute.

• Intawin 400 MG Tablet

  Intas Pharmaceuticals Ltd

• Flutas 400 MG Tablet

  Intas Pharmaceuticals Ltd

• Fabizol 400 MG Tablet

  Unichem Laboratories Ltd

• Zocon 400 MG Tablet

  Fdc Ltd

• Af 400 MG Tablet

  Systopic Laboratories Ltd-Mem

• Are there any missed dose instructions?

  Missed dose of this tablet may be taken later unless it is already time for the next dose.

• Are there any overdose instructions?

  Overdose of Af tablet can worsen the side effects of using the medicine. You may need to seek medical help.

This tablet decreases ergosterol production by disrupting the activity of cytochrome P450, inhibiting the formation of the cell membrane of susceptible fungi like Candida and Microsporum.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  null

  Fluconazole does not interact with alcohol.

• Interaction with Lab Test

  Keep monitoring periodic liver function tests (AST, ALT, alkaline phosphatase) and renal function tests, potassium. As these might drastically be affected by the action of the Af 400 MG Tablet.

• Interaction with Medicine

  This drug interacts with Alprazolam, Atorvastatin, Clopidogrel, Cisapride, Warfarin, Terfenadine, Astemizole, Pimozide, Quinidine, Erythromycin, Halofantrine, Amiodarone, Rifampicin, Hydrochlorothiazide, Alfentanil, Amitriptyline, nortriptyline, Amphotericin B, Anticoagulants, midazolam, triazolam, Carbamazepine, Calcium channel blockers, Celecoxib, Cyclophosphamide, Fentanyl, Olaparib, Ciclosporin, Everolimus, Sirolimus, Tacrolimus, Losartan, Methadone, naproxen, lornoxicam, meloxicam, diclofenac, etc.

• Interaction with Disease

  null

  This medicine is unsuitable for patients with QT prolongation and liver and kidney disorders.

• Interaction with Food

  null

  Fluconazole has no interaction with food.

• Ques : What is Af tablet?

  Ans : This is a medication which has Fluconazole as an active element present in it. This medicine performs its action by killing fungi and destroying the fungal cell membrane.

• Ques : What are the uses of Af 400 MG Tablet?

  Ans : This tablet is a medication, which is used for the treatment and prevention from conditions such as Oropharyngeal Candidiasis, Esophageal Candidiasis, Cryptococcal Meningitis, Vaginal Candidiasis, and Urinary Tract Infection.

• Ques : What are the Side Effects of Af 400 MG Tablet?

  Ans : Here are some side effects of this tablet which are as follows: Headache, Nausea and Vomiting, Abdominal pain, Diarrhea, Skin rash, QT Prolongation, Alopecia, Seizures, and Swelling of face, lips, eyelids, tongue, hands, and feet.

• Ques : What are the instructions for storage and disposal Af 400 MG Tablet?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.