Kelfer 500mg Capsule

Kelfer 500mg Capsule is mainly used for patients suffering from thalassaemia. It helps to bring control the excessive iron in the patient’s body because of repeated blood transfusions and also helps to chelate iron. Extremely high levels of iron in the body can cause several health issues such as diabetes, liver and kidney problems and stunted growth in children.

The serum ferritin levels should be monitored regularly during the treatment. This drug works as a chelator of iron. It attaches to ferric ions (iron III) in the body in a 3:1 (deferiprone: iron) molar ration thereby forming a stable complex that can be eliminated from the body through urine.

It is usually taken in the form of a tablet, 3 times a day, in the morning, afternoon and evening. Although it can be taken without food, it is generally suggested to take it with a meal to prevent nausea that may occur. Some common side effects of this medication include nausea, vomiting and stomach pain. It may also cause your urine to become reddish-brown.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Iron Overload

• Transfusion Dependent Thalassemia

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Hypersensitivity

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Nausea

• Vomiting

• Abdominal Pain

• Arthralgia

• Neutropenia

• Diarrhoea

• Headache

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  It is unsafe to use during pregnancy. There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  There is no data available. Please consult a doctor before consuming the drug.

• Does this affect kidney function?

  There is no data available. Please consult a doctor before consuming the drug.

• Does this affect liver function?

  There is no data available. Please consult a doctor before consuming the drug.

• What is the onset of action?

  The onset of action of this medication is about 5 to 10 minutes.

• How long is the duration of effect?

  The duration of effect of this medication is about 5 to 6 hours.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of this drug, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

The active constituent of this medication by nature is an iron chelator because it combines to ferric ions and takes the form of stable deferiprone: iron or 3:1 complex and removed via urine. Other metals have lowered affinity when it comes to the constituent of this medicine as compared to iron.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Lab Test

  This drug interacts with LFT(liver function test).

• Interaction with Medicine

  This drug interacts with Drugs associated with neutropenia or agranulocytosis, UDP-glucuronosyltransferases (UGTs), and Polyvalent cations.

• Interaction with Disease

  No information available.

• Interaction with Food

  No information available.

• Ques : What is Kelfer 500mg Capsule?

  Ans : This drug is primarily used for patients suffering from thalassaemia. It helps to bring control the excessive iron in the patient’s body because of repeated blood transfusions and also helps to chelate iron.

• Ques : How long do I need to use Kelfer 500mg Capsule before I see improvement in my condition?

  Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition.

• Ques : At what frequency do I need to use Kelfer 500mg Capsule?

  Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

• Ques : Should I use Kelfer 500mg Capsule empty stomach, before food or after food?

  Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

• Ques : What are the instructions for the storage and disposal of Kelfer 500mg Capsule?

  Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children.

• Deferiprone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/deferiprone

• Deferiprone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 9 June 2022].Available from:

  https://go.drugbank.com/drugs/DB08826

• DEFERIPRONE capsule,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=DEFERIPRONE