Acute Myeloid Leukemia - NPM1 gene Mutations Test in Mumbai

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NABL CAP Accredited Mulund West, Mumbai
6500.0 for Acute Myeloid Leukemia - NPM1 gene Mutations
Open today
07:00 AM - 09:00 PM
Mon
07:00 AM - 09:00 PM
Tue
07:00 AM - 09:00 PM
Wed
07:00 AM - 09:00 PM
Thu
07:00 AM - 09:00 PM
Fri
07:00 AM - 09:00 PM
Sat
07:00 AM - 09:00 PM
Sun
08:00 AM - 01:00 PM
Sorry! Your search did not match any lab. Please contact Lybrate's helpline: +91-901-555-9900.
About Acute Myeloid Leukemia - NPM1 gene Mutations Test

Nucleophosmin (NPM1), encoded by the NPM1 gene localized at chromosome 5q35, is a multifunctional nucleo-cytoplasmic shuttling protein that is predominantly localized in the nucleoli. Acute myeloid leukemia (AML) is a clonal disease of hematopoietic progenitor cells, leading to increased numbers of blasts in the blood and/or bone marrow with concurrent suppression of normal hematopoiesis. AML is rapidly being recognized as a heterogeneous disease, with up to 55% of adult cases having nonrandom chromosomal aberrations, which can generally be detected by conventional karyotyping. Cytogenetically normal-AML is less frequent in children than in adults, and accounts for ±20 to 25% of childhood AML cases.

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