MBBS Bachelor of Medicine and Bachelor of Surgery, MD - Obstetrics & Gynaecology, FCPS - Mid & Gynae
IVF Specialist, Mumbai
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39 years experience
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Assisted hatching is performed during which type of fertility treatment?
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Assisted hatching is performed during in vitro fertilization to help an embryo implant properly in the uterus. Many couples experience IVF failure when the embryo fails to implant in the uterus. Women who experience IVF failure can undergo a process called assisted hatching. This is a new laboratory technique in which an embryologist uses the process of micromanipulation to create a hole in the zona pellucida layer of embryos to increase the chances of implantation. Women who experience failed IVF cycles should consult a fertility doctor to consider the option of assisted hatching.
Who is the right candidate for assisted hatching with IVF?
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Women with advanced maternal age may experience IVF failures. If they have two failed IVF cycles, they would need assisted hatching. Women who are older than 38 requires assisted hatching with IVF. This is because their embryos lack sufficient energy for completing the hatching process. Therefore, they need assisted hatching in which the embryo will get implanted successfully into the uterine lining. This technique is helpful for women with a poor prognosis for IVF. Women who are older than 38 should directly opt for assisted hatching with IVF after consulting with a doctor.
The zona pellucida layer of the embryo is ruptured or thinned during assisted hatching.
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The technique of assisted hatching is performed three days after fertilization when the embryo has started to develop. Zona pellucida is a layer that coats the embryo. During assisted hatching, this layer is carefully ruptured or thinned so that the embryo can be implanted successfully. The embryo is then transferred into the uterus one day after the assisted hatching. The embryologist uses a microscope, robotic assistance, and microscopic tools to conduct this process. Antibiotics and steroids may be administered by the doctor to reduce complications.
Assisted hatching with IVF is 100% safe.
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Assisted hatching is not a 100% safe technique. There can be several complications that women might have to face after this process. The embryo can get damaged when the embryologist tries to rupture the zona pellucida layer. It can also damage individual blastomeres, reducing the viability of the embryo. Fertility experts are continually debating if the benefits of this technique outweigh its risks. Before opting for assisted hatching, you should talk to your doctor about the related benefits and risks.
Assisted hatching enhances the chances of IVF success.
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It has been found that assisted hatching results in IVF success. Researchers at the Cornell Medical College of New York have discovered that implantation in women increased with assisted hatching. Women over 38 who have increased FSH level on the third day of the menstrual cycle have also benefitted from assisted hatching. This technique has also helped couples that have faced multiple failed IVF cycles. As assisted hatching is a difficult process, be sure to consult your doctor and work with an experienced embryologist.