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Overview

Panderm+ Cream

Banned
Manufacturer :  Macleods Pharmaceuticals Pvt Ltd
Medicine Composition :  Clobetasol, Ofloxacin, Ornidazole, Terbinafine
Prescription vs OTC : Prescription by Doctor not required

About Panderm+ Cream

Panderm+ Cream helps in the treatment of bacterial infections and fungal infections. It also helps in curing skin infections and dermatoses. It is recommended to apply this cream two times in a day as directed by the doctor.

Panderm Plus Cream contains Clobetasol, Ofloxacin, Ornidazole, Terbinafine as active ingredients. It is a combination of corticosteroids, antifungal, and antibiotics, thus works via multiple mechanisms.

Firstly, it works as an anti-inflammatory by inhibiting the metabolism of arachidonic acid by inhibiting phospholipase A2. Secondly, it decreases ergosterol production by disrupting the activity of cytochrome P450, inhibiting the formation of the cell membrane of susceptible fungi like Candida and Micosporum.

The common side effects of Panderm + cream are Rash, Skin Irritation, Burning and others. Take medical help if these side effects do not go away within a few days. It is recommended to consult your doctor about your medical condition.

In case of a missed dose of this drug, you must take it immediately. It is advised to skip the missed dose if it is time for your next scheduled dose. Pregnant or breastfeeding women should apply this medication only after doctor’s consultation as it may leave some kind of side effects.

Also Read: Quadriderm Cream Uses

    What are the uses of Panderm+ Cream

    What are the contraindications of Panderm+ Cream ?

    What are the side effects of Panderm+ Cream ?

    • Application Site Reactions (Burning Sensation)

    • Dry Skin

    • Redness Of Skin

    • Itching Of Skin

    • Headache

    Key highlights of Panderm+ Cream

    • How long is the duration of effect?

      The duration of effect of this medication is not clinically proven.

    • What is the onset of action?

      The onset of action depends on the skin type and the severity of the skin condition.

    • Is it habit forming?

      No, it is not habit-forming.

    • Is It safe with alcohol?

      Consult your doctor before consuming alcohol.

    • Are there any pregnancy warnings?

      Pregnant women should consult doctor before using this medication.

    • Are there any breast-feeding warnings?

      Breastfeeding women must avoid the application of Panderm Cream as much as possible. Consult your doctor before use.

    • Is it safe to drive while on this medicine?

      It is relatively safe to drive with the cream applied to the affected area unless you experience anything that can affect your alertness or control on coordination.

    • Does this affect kidney function?

      There is no sufficient information regarding this. If you have kidney related issues, you may discuss the implications of the application of cream in such cases.

    • Does this affect liver function?

      You should consult a doctor and discuss the possible risks related to application of this cream that can hamper the functioning of the liver.

    What are the substitutes for Panderm+ Cream ?

    Below is the list of medicines, which have the same composition, strength and form as Panderm+ Cream , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Stick to the time and dosage prescribed by the doctor. Make sure you are taking an adequate amount on time.

    How does this medication work?

    Panderm Cream is a combination of corticosteroids, antifungal, and antibiotics, thus works via multiple mechanisms. Firstly, it works as an anti-inflammatory by inhibiting the metabolism of arachidonic acid by inhibiting phospholipase A2 thus inhibits the production of inflammatory mediators like prostaglandins and leukotrienes. Secondly, it decreases ergosterol production by disrupting the activity of cytochrome P450, inhibiting the formation of the cell membrane of susceptible fungi like Candida and Micosporum. Thirdly, it kills them by seeping into their cells through diffusion and damaging DNA and other critical biomolecules through the formation of reactive nitro radicals. Lastly, works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.

      What are the interactions of Panderm+ Cream ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        You must consult a doctor if you have a drinking habit as he/she will be able to guide you through this in a better way.

      • Interaction with Medicine

        Panderm Cream can interact with certain medicines like acetazolamide, aminoglycosides, antacids, aspirin, antidiabetics, barbiturate, calcium-channel brokers and carbamazepine.

      • Interaction with Disease

        The cream can interact with certain diseases and cause serious side effects. You must consult a doctor if you suffer from fungal infection in lungs or skin, inflammatory disease, glaucoma and other inflammatory diseases.

      • Interaction with Food

        There is no specific food group that can cause a serious side effect on interaction with the cream. It is better that you discuss with your doctor about any food allergies that you have.

      FAQs about Panderm+ Cream

      • Ques : What is Panderm Plus Cream?

        Ans : Panderm Cream is an ointment that contains Clobetasol, Ofloxacin, Ornidazole, and Terbinafine as active ingredients. It is known to treat infections such as:

        • Skin infections
        • Vaginal infections
        • Rheumatoid arthritis
        • Bacterial infection
        • Preoperative preparation of the bowel
        • Cutaneous infections
        • Eye infection

      • Ques : What are the side effects of Panderm Plus Cream?

        Ans : Panderm Plus has some known side effects such as:

        • Inflammation of skin
        • Irritation
        • Dryness

      • Ques : Is Panderm Plus safe during pregnancy?

        Ans : It is not safe to be applied during pregnancy as it contains Gramicidin, Neomycin Sulphate, Nystatin and Triamcinolone Acetonide as active ingredients. You are advised to consult the doctor before use.

      • Ques : How frequently I can apply Panderm Cream?

        Ans : Frequency of applying this cream dependent on the patient’s skin type and health issues. Therefore it is advised to consult the Doctor before using it.

      • Ques : Can Panderm+ Cream be used for infections of Skin Infection?

        Ans : Yes, It can be used to treat skin infection. Moreover, it is also helpful in curing Bacterial and Vaginal Infections and Respiratory Tract Infections.

      • Ques : How long do I need to use cream before I see improvement of my conditions?

        Ans : The usage of cream for proper improvement depends on the patient’s health. The duration of the application is also dependent on the patient.

      • Ques : Is Panderm Cream safe to use when pregnant?

        Ans : No, It is not safe to use during pregnancy as it is a steroid medication and its constituents can harm the skin.

      References

      • Ofloxacin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ofloxacin

      • Ornidazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ornidazole

      • Clobetasol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/clobetasol

      • Terbinafine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/terbinafine

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Yuvraj Arora MongaMD-Pharmacology, MBBSSexology
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