Pentab D 20 Mg/30 Mg Tablet

This medication is indicated for treating GERD (Gastro-esophageal reflux disease), which does not respond to Pantoprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Pentab D 20 Mg/30 Mg Tablet is a combination of Domperidone and Pantoprazole. The active ingredients fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

It is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

This medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Pentab D 20 Mg/30 Mg Tablet if you have the following conditions:

• An allergy to Pentab D 20 Mg/30 Mg Tablet or any other ingredient of this medicine
• Bleeding problems or blockage in your stomach or in the intestine
• Tumour in the pituitary gland
• Cardiac disease
• Incorrect levels of magnesium, potassium or calcium in the blood
• Severe/moderate liver impairment

• Gastroesophageal Reflux Disease

• Peptic Ulcer

• Allergy

• Tumor Of Pituitary Gland

• Heart Diseases

• Skin Rash

• Diarrhoea

• Headache

• Stomach Pain

• Dizziness

• Weakness

• Dry Mouth

• Cough

• Rhinitis

• Flatulence

• Insomnia

• How long is the duration of effect?

  The effect of this medicine lasts up to 6 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed within 30 to 60 minutes of administration.

• Are there any pregnancy warnings?

  This medicine should be avoided by pregnant women unless suggested by the doctor.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  The medicine is suggested to be ignored by breastfeeding mothers.

• Are there any missed dose instructions?

  Skip the missed dose and resume with the next scheduled dose at the right time.

• Are there any overdose instructions?

  Contact your doctor if an overdose is suspected.

This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Lab Test

  The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.

• Interaction with Medicine

  Medicine

  Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

• Interaction with Disease

  Disease

  Patients suffering from liver disease, osteoporosis and hypomagnesemia should exercise caution.

• Ques : What is Pentab D 20 Mg/30 Mg Tablet?

  Ans : Pentab tablet is a medication which has Domperidone and Pantoprazole as active ingredients present in it. This medicine performs its action by obstructing the release of acid in the stomach.

• Ques : What are the uses of Pentab D 20 Mg/30 Mg Tablet?

  Ans : Pentab tablet is used for the treatment and prevention from conditions and symptoms of diseases like Heartburn, esophagus inflammation, stomach and intestinal ulcers.

• Ques : What are the Side Effects of Pentab D 20 Mg/30 Mg Tablet?

  Ans : Eczema, Diarrhea, Galactorrhoea, Breast tenderness, Headache and Skin rashes are possible side effects.

• Ques : What are the instructions for storage and disposal Pentab D 20 Mg/30 Mg Tablet?

  Ans : Pentab d tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : Should I use Pentab D 20 Mg/30 Mg Tablet empty stomach, before food or after food?

  Ans : The salts involved in this medication, work effectively on an empty stomach.

• Ques : How long do I need to use Pentab D 20 Mg/30 Mg Tablet before I see improvement of my conditions?

  Ans : This medication should be consumed, until the complete eradication of the disease.

• Ques : Is there any food or drink I need to avoid?

  Ans : The diet should be normal, there is nothing as such to avoid.

• Ques : Will Pentab D 20 Mg/30 Mg Tablet be more effective if taken in more than the recommended dose?

  Ans : Excess usage of this medication can trigger side effects.

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 27 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/domperidone

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 27 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184

• Pantoprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 27 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/pantoprazole

• Pantoprazole- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 27 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00213