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Overview

Germenta 40 MG Injection

Manufacturer :  Zydus Cadila
Medicine Composition :  Gentamicin
Prescription vs OTC : Prescription by Doctor required

About Germenta 40 MG Injection

Germenta 40 MG Injection helps in the treatment of a range of bacterial infections. It belongs to a group of drugs called the aminoglycoside antibiotics. The drug stops bacterial growth thus preventing or treating the infection.

The drug is mostly administered via an injection as per the doctor’s guidance. An injection may be administered after a span of 8 hours, depending on the health of the patient, age, weight, extensity of the infection and the body’s reaction to the medication. Generally certain laboratory tests, for instance a kidney function test may be done before administering the drug so as to determine the dosage that can be given. Such tests are regularly done once Germenta 40 MG Injection is started to check the progress of the drug and its effect on the body.

Certain common side effects of the drug include vomiting, feeling nauseous, appetite loss and stomach upset. Redness or itching at the site of the injection is very rare, if this does occur or any of the side effects worsen contact your doctor and seek relevant medical advice.

Patients should provide doctors their detailed medical history, including information about any allergies or existing health condition they suffer from before taking the injection. Especially if you suffer from medical problems like cystic fibrosis, kidney issues, Parkinson’s, or deafness inform your doctor and discuss the various possibilities of the drug use. Expecting women are also not encouraged to take this drug as it may harm the fetus. The drug is known to pass into the breast milk, but most doctors consider it safe for breast feeding mothers.

Germenta 40 MG Injection should be kept away from the reach of children as well as pets. In case of a missed dose, get in touch with your doctor for a new schedule. A double dosage can result in severe complications.

    What are the uses of Germenta 40 MG Injection

    • Bacteremia

      Germenta 40 MG Injection helps in treating bacteremia, an infection of the blood caused by Staphylococci and Streptococcus pyogenes.

    • Intra-Abdominal Infections

      Germenta 40 MG Injection prevents intra-abdominal infections caused by Helicobacter pylori, Staphylococci and Streptococci.

    • Bacterial Meningitis

      Germenta 40 MG Injection helps in managing meningitis, an inflammation of the protective membranes that surround the brain and spinal cord, caused by Streptococcus pneumoniae and Neisseria meningitidis.

    • Osteomyelitis

      Germenta 40 MG Injection is helpful in curing bone and joint infections such as Osteomyelitis caused by Staphylococci and Streptococci species.

    • Skin And Soft Tissue Infections

      Germenta 40 MG Injection manages skin and soft tissue infections caused by Staphylococcus aureus and Streptococcus pyogenes.

    • Pyelonephritis

      Germenta 40 MG Injection helps against Pyelonephritis, a kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

    What are the contraindications of Germenta 40 MG Injection ?

    • Allergy

      Germenta 40 MG Injection or any other aminoglycosides should not be used if you are allergic to it.

    What are the side effects of Germenta 40 MG Injection ?

    Key highlights of Germenta 40 MG Injection

    • How long is the duration of effect?

      The effect of this medicine lasts for a duration of about 6 to 8 hours.

    • What is the onset of action?

      The top effect of this medicine is observed within 30 to 90 minutes of administration.

    • Are there any pregnancy warnings?

      This medicine is not suggested for pregnant women. Consult your doctor before using it.

    • Is it habit forming?

      No habit forming tendencies are reported for Germenta 40 MG Injection.

    • Are there any breast-feeding warnings?

      The medicine is known to excrete through human breast milk. It is always suggested to discuss with the doctor about benefits and risks associated with Germenta 40 MG Injection.

    What are the substitutes for Germenta 40 MG Injection ?

    Below is the list of medicines, which have the same composition, strength and form as Germenta 40 MG Injection , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose can be taken as soon as possible. However, skip the missed dose if it is almost time for the next scheduled dose.

    • Are there any overdose instructions?

      Consult a doctor if symptoms of overdose are suspected.

    How does this medication work?

    Germenta 40 MG Injection belongs to the class aminoglycosides. It works by binding to the 30S subunit of the bacterial ribosomes thus inhibits the protein synthesis in the bacteria and stops the growth of the bacteria.

      What are the interactions of Germenta 40 MG Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is not known. Consult your doctor before consumption.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Furosemide

        Germenta 40 MG Injection is not recommended with loop diuretics due to the increase in the risk of kidney injury and hearing problem. Inform the doctor if you are receiving these medicines and any symptoms of hearing loss, dizziness, numbness should be reported immediately. Frequent monitoring of kidney function tests is necessary. An alternate medicine should be considered based on the clinical condition.

        Nonsteroidal anti-inflammatory drugs

        Use of Germenta 40 MG Injection with nonsteroidal anti-inflammatory drugs like diclofenac, aspirin may increase the risk of kidney injury. Any symptoms of swelling, weight gain, increased thirst, changes in the frequency of urination should be reported to the doctor. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

        Cephalosporins

        Use of Germenta 40 MG Injection with cephalosporins like ceftriaxone, cefotaxime may increase the risk of kidney injury. Any symptoms of swelling, weight gain, increased thirst, changes in the frequency of urination should be reported to the doctor. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.
      • Interaction with Disease

        Dehydration

        Always consume good amount of water to avoid any kidney injury and hearing problem caused due to dehydration.
      • Interaction with Food

        Food

        Information not available.
      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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