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Last Updated: Oct 23, 2019
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Diabetes + Obesity & PCOS - Did You Know It Is The New Epidemic?
Dr. Ashish KaleGynaecologist • 24 Years Exp.MD - Obstetrics & Gynaecology, Diploma In Endopelvic Surgery, FICS
PCOS is a common hormonal abnormality seen mostly in reproductive age groups
Affects about 30% females
Diagnosis is by Rotterdam criteria: 2/3 should be present
- Oligo/anovulation
- Polycystic ovarian morphology
- Hyperandrogenism
It also affects other metabolisms like insulin resistance causing diabetes, impaired glucose tolerance and this ultimately exacerbates obesity
- It has a genetic predisposition.
- Pcos can either be lean PCOS or obese PCOS.
- This classification is important to categorize the causal effect and treatment also differs
- Insulin-mediated glucose disposal reflects the action of insulin on muscle cells and this is decreased by 30-40% in women with PCOS.
- This is further worsened with obesity.
- The endogenous glucose production is also affected and this causes glucose intolerance.
- They also have menstrual irregularities and infertility due to lack of mature egg ( anovulation ) production.
Treatment
- Change in lifestyle and diet
- Exercise
- Weight reduction
- Drugs to regularise menses and antidiabetic drugs
- Ovulation-inducing agents with or without IUI for subfertility
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