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Last Updated: Jan 10, 2023
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Loose Anagen Syndrome - How to Know If You are Suffering from it?

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Dr. Sandesh GuptaDermatologist • 29 Years Exp.MBBS, Diploma in Venerology & Dermatology (DVD)
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Loose anagen syndrome, which falls under the discipline of trichology, is a hair and scalp disorder characterized by the presence of anagen hair having abnormal morphology, which can be painlessly plucked or pulled from the scalp, with ease. The overall appearance shows a thinned hair growth (especially at the back), with growth stopping at the nape of your neck. This disorder is most commonly noted in young children, in girls more so than boys.

Causes
The exact cause for loose anagen syndrome is yet unknown. The predominating speculation about the same, however, suggests that an abnormality found in the anchoring mechanism of the hair might be at the cause of the disorder.

The Science

The inner sheath of the root plays an integral part in helping to anchor the sheath of the hair within the hair follicle. When afflicted by loose anagen syndrome, abnormalities in the keratinization of your inner root sheath, caused as a result of gene coding mutations for cytokeratins are considered to be at the root of the disorder. This leads to impairment in the adherence of the damaged or deformed shafts of hair, to their follicles. This may lead to premature cessation, especially of the anagen phase, and may result in a reduction of hair length.


Contributing Factors
1. Race: Most commonly noted in white skinned people, especially those with blond hair. It may, however, even be evident in case of those of Asian or African descent.
2. Sex: It has a higher incidence for females than males.
3. Age: The most frequently reported issues occur in young blond girls between the ages of 2 to 5 years. However, adults have also been known to suffer from it.

Symptoms
1. If you are affected by this disorder, you will find that hair density and length atypically increase over time and then darken in color.
2. Also, it can be easily uprooted from the scalp and hair pulling causes little to no pain.

Treatment
Minoxidil is usually considered to be a good remedy to this problem. If you wish to discuss about any specific problem, you can consult a dermatologist.

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