Sir, At the outset please accept my greetings and salutations. May I have your valued opinion regarding my sister who was initially diagnosed with Burkit's lymphoma and was treated with CODOX-M/IVAC four cycles .PET revealed a near complete remission ,however, the disease relapsed within a month. She was later put on R-CHOP two cycles, although negative for CD20. Of late she is now being treated with Nivolumab ,three doses of 200 mg each administered, third is due for tomorrow. They have a diagnostic dilemma, now treating it as Plasmablastic lymphoma. I'm extremely confused ,my sister has uncontrolled ascites inflicting severe discomfort. May I solicit your advice as to what should I do further in order to get get relieved of this difficult situation. I understand your being an awfully busy person but if you consider paying attention to my case ,I shall be not only grateful to you but shall pray for your and your family's wellbeing. Thanks and regards! Very sincerely yours,