Am 24 years old, I have gestational trophoblastic neoplasia. The gynaecologist advises me to consult an oncologist. 2 months before they had given me methotrexate injections, it reduces beta hcg level slowly and suddenly it rises, after 4 cycles of methotrexate they said that methotrexate fails and they changed my medicine, from one month they are giving me dactinomycin. My hcg level decreases from 155 to 105 in first cycle, in the second cycle it reduces from 105 to 47.9, in 3rd cycle it reduces from 47.9 to 39. This time it reduces very low. Why doctor? Anything fault? Today am going to receive the 4th cycle. Why it's dropping slowly?