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The serum bactericidal test (sbt) has been used for almost 40 years to monitor therapy in patients with bacterial endocarditis, osteomyelitis, and other serious infections. The sbt is ordered to determine the maximum bactericidal dilution of serum after the administration of antibiotics. Prior to the test, it is important to inform the doctor about any medication that you may be taking. Blood is drawn through venipuncture, mostly from the forearm of the person. Blood is collected from the patient in order to obtain 1 ml of serum. If the serum is collected in a different place it should be transported as quickly as possible under sterile conditions and not be refrigerated. If the sample is collected onsite then it must be a peak specimen, collected in an sst tube in the following manner - ? 30 minutes after i.v administration of antibiotics ? 1-hour post-i.m. Administration of antibiotics ? 1-2 hour after an oral dose of antibiotics ? trough specimen taken before the next dose of antibiotic.
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