Varicella Zoster DNA, PCR Test

Chickenpox is a relatively benign illness in childhood, but in adults, it occurs with great severity and with complications that can be fatal. Normally, the diagnosis is made only by the clinical signs of the disease. The Varicella-Zoster-DNA-PCR medical investigation is used to detect varicella-zoster virus (VZV) DNA in the cerebrospinal fluid of patients with VZV infection associated with neurological symptoms. This test is a supportive test for the early diagnosis of VZV linked neurological disease. Positive results were obtained in three of five children with post-chicken pox cerebellitis and in seven of seven herpes zoster patients with neurological symptoms.

Varicella-zoster Virus DNA does not require any major preparation. If you are having an annoying health problem or might have suffered from any in the past, and have any allergy, inform your doctor. Before going for Varicella-zoster Virus DNA ensure your doctor knows every medicine you take. The test requires whole blood or throat swab sample for the examination. Bronchial samples wash can also be used as a reference. There is no restriction on eating and drinking. Take the normal regular diet. The liquid intake has to be increased.

In people with conciliation resistant systems, even when VZV disease is identified by employing laboratory test, it may be difficult to distinguish between vermicelli and disseminated herpes zoster by physical examination or serological testing. In these examples, a history of Varicella-Zoster-DNA-PCR exposure or of a rash that began with a dermatomal pattern, along with results of VZV antibody testing at or previous to the time of rash onset may assist guide the diagnosis.

For the blood spot method collect a sufficient quantity (minimum 1 mL) of blood with a lancet onto both of the defined areas on the filter strip in a lavender-top EDTA tube so that the spot expands to the circular border.
Air dry totally previous to placing them inside a plastic bag.
• Place the strips in a sealable plastic bag. Once the blood example has totally desiccated, it is satisfactory to bundle them with a rubber band and place them in a single bag.
• Another significant examination is blood serum test. The venous blood specimen is collected in a serum separator tube.
Allow clotting of specimen at room temperature.
The centrifuged and refrigerated sample is tested.