Doxorubicin 50Mg Injection Health Feed

Asked for Male, 19 years old from Udaipur

How to increase Lvef of heart. My mom is suffering from low lvef due to side effect of Doxorubicin.

Dr. Udaya Nath Sahoo91%(2203 ratings)

MBBS

Internal Medicine Specialist•Kendujhar

Hello,
Thanks for your query on Lybrate
"As" per your clinical history is concerned, do take treatment for underlying pathology only, so to know the present status do few investigations-
1) Thyroid function test
2) Kidney function tests
3) Liver function test
4) B-type natriuretic peptide (BNP)
5) ECG/ECHO/Cardiac catheterization
Do take treatment as per exact type only and follow lifestyle modifications like this -
1) Controlling high blood pressure, high cho...more

Asked for male, 43 years old from Greater Noida

I am suffering with pmbcl non gcb cancer stage 1b. Already taken 4 cycle of chemo nd 2 r remaining. R-chop (vincristine 1.5 mg doxorubicin 35 mg etoposide 180 mg diluting in 500 ml ns given with the speed of 10 ml per hour from day 2 to day 5, rituximab 375 mg first day. Cyclophosphamide 750 mg day 6) please advise whether it is a wright treatment. My age is 43 male.

Dr. Atul Narayankar

DNB MEDICAL ONCOLOGY, MD MEDICINE, MBBS,...read more

Oncologist•Mira Bhayandar

Hello.
Regimen given this way is known as r dose adjusted epoch and not r chop. I will not comment on dosages as it will be decided by treating oncologist based on patient tolerance. Typically after completing such 6 cycles. After a gap of at least 2 months. We do a repeat pet ct scan to assess response and rule of any additional role of any therapy. Thank you.

Health Query

My mother 38 yr old had underwent operation for fibroid uterus with serous cystadenoma rt ovary 10yrs back by a general surgeon and she was doing well for almost 6yrs. But then she had pain abdomen vague pain. We consulted gynecologist and she referred her to oncologist suspecting a malignancy. She was diagnosed as stage 3c disseminated ovarian carcinoma in the year 2013. She had gone through 6 cycles of paclitaxel and cisplatin. 6 cycles of doxorubicin still ca125 remained high, refractory to treatment then changed to etoposide. My doubt is does there is any negligence from the side of general surgeon who had done surgery in 2006. As he said that he is not able to respect some tissue so he left it.

Dr. Asha Khatri90%(4251 ratings)

MD - Obstetrtics & Gynaecology

Gynaecologist•Mumbai

What was the histopathology report you should have gone for follow up at the regular interval of 6 months

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Asked for female, 53 years old from Akola

2013-mastectomy surgery followed by chemotherapy (6) (doxorubicin) and radiotherapy (25) followed by ai therapy including tamoxifen citrate 20 mg (5 yrs) 2018- metastasis in lumber spine along l3-l4 region treated by palliative radiotherapy (5 of 20 gy dosage) followed by ai therapy including letrozole 2.5 mg+palbociclib+monthly zoledronic acid 4 mg inj. But due to some affordability issues were unable to continue it. Now 2020- metastasis progressed to retroperitoneal region proximal to left para-aortal lymph nodes as per latest mri screening. From last few months she is suffering from excruciating pain in lumber spine that radiates to her ribs and intensifies during night. So for current condition she has already completed palliative radiotherapy (10) but that was of no use to her in terms of pain management or tumor suppression. So she is currently on chemotherapy treatment and completed 3/6 of paclitaxel100 mg+carboplatin. Our problem is that she is suffering from side effects of chemo including nausea, vomiting, diarrhea and abdominal cramps. Please help us to get her relieve from this condition.

Dr. Partha Mukhopadhyay

MBBS, MD - Oncology, DNB Radiation Oncol...read more

Oncologist•Delhi

While these may be the side effects of chemotherapy, they may also be a subtle pointer towards drop in white blood cell counts specially if the patient is taking the chemotherapy on a weekly basis. The patient also needs good pain management.

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