I had left pleural effusion and I am on ATT (rcinex, pz 1500, ethambutol 1200) for 1.5 month. On the start of treatment due to liver problem rifampicin was stopped for a week and levofloxacin 500 was added and after 1 week rifampicin 450 (earlier 600) started again and after that I am normal but doctor tried to introduce rifampicin 600 (as my weight is 67 kg) but whenever I took rifampicin 600 I feel very weak and my head, palm ,ears get heated and I feel hot so I reverted to rifampicin 450 (attempted 3 times). Sir is this dose of rifampicin sufficient and is there any chance of getting MDR tb due to low dose (I never skipped a single dose. Rcinex 450/300, pz 1500, combutol 1200, levofloxacin 500)