My mother aged 79 years was having trembling hand since 25 years and doctors concluded as non parkinson. Recently apart from trembling hands her jaw also started trembling .Doctors diagnosed as parkinson and they prescribed 1.Syndopa 110 half tablet thrice a day. 2. pacitane 2 mg twice a day 3.lonazep 0.2 mg bed time and 4.Betacap bed time. There was a good improvement in her trembling, but she started talking to herself and behaviour changes. This change occurred only after taking these medicines. Request advice

Dr. Sreenivasan Vazhoor RamsinghPsychiatrist9yrs exp

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Hi, This is a very common situation in people suffering from Parkinsonism and you might be correct in assuming the symptoms of talking to herself are due to the medicines. Syndopa actually increases the dopamine levels in your brain which could lead to increase in symptoms like delusions and hallucinations. However if we try to treat the talking to self, this might further decrease dopamine levels and in turn increase trembling and parkinsonian features. So a delicate balance needs to be maintained between the two. This would be best done by a neurologist and psychiatrist working in combination with each other but please do not stop any medication without doctor's advice.  

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